Payloads: Cardinal Heart 2.0: The crew recorded microscopy video for the tissue samples in the Biocells. A previous investigation showed that four weeks of microgravity exposure caused significant changes in heart cell function and gene expression that could lead to long-term damage or cardiac muscle atrophy. Effect of Microgravity on Drug Responses Using Heart Organoids …
Payloads: Engineered Heart Tissue-2 (EHT-2): The crew gathered the EHT-2 tissue chambers and performed the steps necessary to exchange the media, obtain samples for later analysis, and add treatments to the appropriate tissue growth areas. A Human iPSC-based 3D Microphysiological System for Modeling Cardiac Dysfunction in Microgravity-2 (Engineered Heart Tissues-2) continues work with 3D cultured …
Payloads: Human Research Facility Veggie Profile of Mood States (Veggie POMS): A POMS short form questionnaire was completed using the Data Collection Tool (DCT). The Pick-and-Eat Salad-Crop Productivity, Nutritional Value, and Acceptability to Supplement the ISS Food System (Veggie) investigation is a phased research project that includes Veg-04A, Veg-04B, Veg-05, and HRF Veg including HRF …
Payloads: Manufacturing Device (ManD): The crew replaced the feedstock canister, extruder, and build platform in ManD to enable a test object to be printed. Following a failed print attempt, the crew manually fed the feedstock into the extruder to allow another print attempt. The Additive Manufacturing Facility (AMF) enables the production of components on the …
Payloads: BioFabrication Facility (BFF): In order to put the tissue cassette in a good configuration, the crew removed the curing lid and installed the print lid. Using 3D biological printers to produce usable human organs has long been a dream of scientists and doctors around the globe. However, printing the tiny, complex structures found inside …
Payloads: Foams and Emulsions Sampling: An experiment-1 protocol session was performed, which results in the production of an emulsion. In this protocol, the emulsion is formed by mixing an aqueous solution with an oil. The emulsion is observed in the Keyence Research Microscope Testbed (KERMIT) and then “cured” to preserve it for later analysis. Foams …
Northrup Grumman – 18 (NG-18) Cygnus Reboost: Today, the ISS successfully performed a 0.9 m/s reboost using Cygnus Delta Velocity Engine (DVE) thruster starting at 16:03 GMT with a burn duration of 15 minutes and 21 seconds. This reboost is the first of three reboosts to set up the two-orbit rendezvous for 84P Progress currently …
Payloads: BioFabrication Facility (BFF): Vials were inserted into the BFF that contained Cell Cassette 20510 in order to re-attempt a print session from the previous day’s aborted session. Four cleaning (Bio-ink) syringes were swapped out, media was applied into the BFF and tissue printing was initiated. The Cassette was removed, and Cassette 20511 was installed …
Payloads: Ampli Space Pharmacy: Ampli Space Pharmacy hardware was stowed. The Ampli Space Pharmacy investigation studies the properties of chemical reactions of fluids flowing through membranes in microgravity. Researchers can use resulting information to refine an existing organic synthesis and bioprocessing approach to produce new compounds. This modular approach could provide a way to make …
Payloads: Engineered Heart Tissues-2: A media change, sampling and assigned treatment dosing was performed on each Tissue Chamber on Saturday. Engineered Heart Tissues-2 continues work with 3D cultured cardiac muscle tissue to assess human cardiac function in microgravity. Previous work with 3D cultures in space detected changes at the cellular and tissue level that could …
