Leveraging Aerofly’s proven Rego-LIFT system, this solution demonstrates near-vertical regolith conveyance for oxygen in-situ resource utilization (ISRU). By refining motor scaling, system architecture, and energy budgeting, their approach directly addresses a NASA shortfall, optimizing material handling for efficient oxygen extraction from lunar regolith.
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The Ambrosia Space team is building scalable in-space biomanufacturing systems for large-scale protein and nutrient manufacturing for long-duration human spaceflight. Key to this solution is the capability to process large volumes of liquid-based cell culture efficiently in reduced and micro-gravity environments.
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The Carthage College MUT technology uses phased-array ultrasonic transducers to form, direct, and collect helium bubbles into a controlled gas pocket (i.e., ullage), near the vent port. The innovation extracts dissolved helium directly from the propellant — eliminating fuel-consuming settling burns. This enables gas-only venting with minimal propellant loss.
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The HERMES automated genetic material extraction solution for diverse biological samples was developed by Ecoatoms to reduce astronaut time spent on research and development procedures. This innovation advances human-scale logistics and utilization in space, reducing significant costs and allowing astronauts to focus on critical missions while automation handles complex laboratory tasks with precision and consistency.

Guinn Partners’ IMPRESS technology supports affordable rideshare missions and enables Mars swarm deployment for small-scale spacecraft. After an aluminum air brake ensures controlled descent, penetrators embed 50 cm and deploy a 150-g payload for resource reconnaissance. An ultra-high frequency radio beacon aids precision landing for future missions.
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The CELS technology is an autonomous biological payload developed by Helogen Corporation to enable sample handling and preparation for in-orbit analysis. This technology focuses on ensuring high-quality biological experimentation comparable with state-of-the-art ground-based research. It is designed for suborbital, hosted orbital, commercial low Earth orbit destination, and CLPS (Commercial Lunar Payload Services) use.
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Juno’s novel, high-thrust, high-efficiency propulsion system utilizes rotating detonation rocket engine technology powered with nitrous oxide and ethane, non-toxic propellants that are storable and self-pressurizing. The product leverages the 5–10% higher specific impulse of the RDRE technology to be competitive with current hypergolic bi-propellant solutions.
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This technology developed by Space Dust Research & Technologies uses an electron beam to charge particles to mitigate dust hazards for exploration on dust-rich airless bodies, like the Moon. It has demonstrated cleaning efficacy up to 92% for various surfaces, including spacesuits, solar panels, optical lenses, and thermal blankets.
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Commercial Orbital System for Microgravity In-Space Crystallization (COSMIC) is a prototype processing and re-entry system that can be hosted on readily available commercial orbital platforms. The re-entry vehicle is engineered for high-cadence payload return of materials manufactured in space. The recoverable COSMIC payload aims to enable high-temperature silicon crystal growth in microgravity and support scalable, low-cost in-space manufacturing.
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The e5 Lab’s MARS-C provides an electrochemical in-situ resources utilization (ISRU) approach to producing oxygen, hydrogen, and C1 and C2 hydrocarbons at Martian temperatures and pressures. Using water with dissolved and suspended minerals from the Martian regolith and atmospheric carbon dioxide may enable simultaneous electrolysis of the brine and gas to produce hydrocarbons and oxygen on Mars.
›› View the UTSA application video