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ISS On-Orbit Status Report

ISS Daily Summary Report – 12/09/2020

Payloads

Cardinal Heart: The crew deployed and used the Life Science Glovebox to change the media in one of four Cardinal Heart Tissue Habitats. Effect of Microgravity on Drug Responses Using Engineered Heart Tissues (Cardinal Heart) studies the effects of change in gravitational force on cardiovascular cells at the cellular and tissue level using Engineered Heart Tissues (EHTs). Microgravity significantly affects heart tissues that perform work and exert an opposite force to gravity and is known to cause molecular and structural abnormalities in cells and tissues that can lead to disease. The investigation could provide new understanding of similar heart issues on Earth and help identify new treatments.

Rodent Research-10 (RR-10): The crew transferred rodents from the SpX-21 Dragon into the ISS Rodent Habitats. Tissue degeneration and failure of tissue to regenerate normally in microgravity are becoming increasing concerns for sustaining life in space. The CDKN1a/p21 pathway is known to be a key molecular mechanism involved in inhibiting tissue regenerative processes, and scientific evidence suggest it is required for the arrest of regenerative bone formation observed in microgravity.

Space Organogenesis: The crew performed Ssample inserts and medium exchanges for the Space Organogenesis experiment. The Development of Advanced 3D Organ Culture System Utilizing the Microgravity Environment (Space Organogenesis) investigation demonstrates growth of organ buds from human stem cells in three-dimensional (3D) cultures in microgravity. Researchers plan to use these cultures to observe growth of the organ buds and analyze changes in gene expression. Cell culture on Earth needs supportive materials or forces to achieve 3D growth, but in microgravity cell cultures likely can expand into three dimensions without those devices.

Vascular Echo: The crew completed the 13-hour data collection period using the Blood Pressure monitoring hardware and downloaded the data to the ground. Cardiac and Vessel Structure and Function with Long-Duration Space Flight and Recovery (Vascular Echo) examines changes in blood vessels, and the heart, while the crew members are in space, and then follow their recovery on return to Earth. The results could provide insight into potential countermeasures to help maintain crewmember health, and quality of life for everyone.

Systems

Short Extravehicular Mobility Unit (SEMU) Launch Enclosure Briefing: FE-12 participated in a briefing which covered preparing EMU 3008 for return, removal of EMU 3015 from the SLE and installing EMU 3008 into the SLE in the Dragon cabin. This swap is planned for tomorrow.

Cargo Transfer Ops: The crew continued transferring cargo from the Dragon vehicle to the ISS.

Completed Task List Activities:

  • None

Today’s Ground Activities:

  • MT translate from WS7 to WS5
  • Dragon transfer ops
  • Payloads support

Look Ahead Plan

Thursday, 12/10 (GMT 345)
Payloads:

  • Cardinal Heart Habitat (2) medium exchange (NASA)
  • Space Organogenesis Medium changes and Microscope ops (JAXA)
  • Moderate Temp PCG prep (JAXA)
  • Fiber Optics Sample exchange (NASA)
  • APM data transfer and Node 2 to Lab install (NASA)
  • NanoRacks Module 9 Ops 2 (NASA)
  • AstroRad Vest Fam (NASA)
  • Food Acceptability survey (NASA)
  • ACME CIR Bottle exchange (Joint)
  • EHS BioMole BMS stow (NASA)

Systems:

  • Dragon transfer ops

Friday, 12/11 (GMT 346)
Payloads:

  • Toilet Crew Conf (NASA)
  • Space Organogenesis sample fixations and closeout (JAXA)
  • JAXA low temp PCG prep (JAXA)
  • Food Physiology Diet Brief (NASA)
  • ARS Thermal Amine Scrubber (TAS) Sampling System Install and troubleshoot (NASA)
  • Plant Habitat-02 Thinning (NASA)
  • Fiber Optics Sample exchange (NASA)
  • AstroRad vest don and Doff and Survey (NASA)
  • Rodent H2O check (NASA)
  • ISS Experience Hardware stow (NASA)
  • MonoClonal Antibodies PCG card fills (NASA)

Systems:

  • Dragon emergency response OBT

Saturday, 12/12 (GMT 347)
Payloads:

  • Rotifer B2 Verification (ESA)

Systems:

  • Crew off duty; housekeeping

Sunday, 12/13 (GMT 348)
Payloads:

  • Phospho-Aging Urine collect and MELFI insert (JAXA)
  • Plant Habitat-02 Leaf Gather (NASA)
  • Micro-14A Sampling (NASA)
  • LSG Front Glove Swap (NASA)
  • Standard Measures Blood setup (NASA)
  • Cardinal Heart Microscope Ops (NASA)

Systems:

  • None

Today’s Planned Activities:
All activities are complete unless otherwise noted.

  • LSG Work Volume Deploy
  • Space Organogenesis Item Gathering
  • LSG Primary Crew Restraint Unfold
  • Crew Dragon Tablet Sync
  • ISS CREW/SSIPC CONFERENCE
  • Environmental Health System (EHS) Biomole Maintenance Work Area Prep 2
  • Crew Dragon Tablet Stow
  • BioMole MELFI Retrieve
  • ISS HAM Columbus Pass
  • BioMole Part 3: DNA Prep and Sequencing
  • XF305 Camcorder Setup
  • MELFI Medium Retrieval
  • Space Organogenesis Sample Check
  • Microscope Sample Installation 2
  • Space Organogenesis Compact Flash Memory Card 64GB Data Transfer
  • Rodent Research Animal Transfer 1
  • Cardinal Heart Tissue Chamber Media Change and Sample
  • ExtraVehicular Activity (EVA) Short EVA Mobility Unity Launch Enclosure (SLE) Training Crew training in preparation of EMU SLE rotation activities
  • Ultrasound 2 HRF Rack 1 Power On
  • Health Maintenance System (HMS) Ultrasound 2 Scan Prep
  • Health Maintenance System (HMS) Ultrasound 2 Scan performed by a Crew Medical Officer (CMO)
  • Health Maintenance System (HMS) Ultrasound 2 Scan
  • Health Maintenance System (HMS) Ultrasound 2 Scan performed by a Crew Medical Officer (CMO)
  • Health Maintenance System (HMS) Ultrasound 2 Scan
  • Preparation for working with МИМ2 smoke detectors (ИДЭ-4)
  • Cardinal Heart MELFI Sample Insertion Operations Session
  • Health Maintenance System (HMS) Profile of Mood States (POMS) Questionnaire
  • Health Maintenance System (HMS) Ultrasound 2 Post Exam
  • Microscope Sample Replacement 1
  • Cardinal Heart Node 2 Camcorder Video Setup
  • Cardinal Heart Tissue Chamber Media Change and Sample
  • Rodent Research Animal Transfer 2
  • Cargo Transfer to Dragon
  • XF305 Camcorder Setup
  • Microscope Sample Replacement 2
  • Space Organogenesis Medium Exchange 1
  • Vascular Aging 13-Hour Blood Pressure Monitoring Conclude Alternate
  • Cardinal Heart MELFI Sample Insertion Operations Session
  • Cardinal Heart Node 2 Camcorder Video Setup
  • Delta file prep
  • ExtraVehicular Activity (EVA) Short EVA Mobility Unity Launch Enclosure (SLE) Training Crew training in preparation of EMU SLE rotation activities
  • XF305 Camcorder Setup
  • LSG Primary Crew Restraint Fold
  • Microscope Sample Retrieval 2
  • LSG Work Volume Stow
  • Space Organogenesis Medium Exchange 2
  • Rodent Research Transporter Stow
  • Treadmill 2 (T2) Exercise Video Equipment Setup
  • PFA Transfer
  • Space Organogenesis Closeout 2
  • Treadmill 2 (T2) Exercise Video Equipment Stow
  • Program Management/ISS Crew Conference