OSDR Chats Featuring Dr Chris Mason’s Latest Publication

Welcome to “OSDR Chats,” an interview series featuring authors of publications that were enabled by the Open Science Data Repository (OSDR). Researchers share highlights and insights into their work, including the importance of the OSDR and the Analysis Working Groups (AWGs) in their research. This newest interview features Dr Chris Mason from Weill Cornell Medicine, who used three datasets (OSD-530, OSD-569, OSD-571) from the OSDR in his research.

Spaceflight significantly impacts human and murine physiology, even during short durations. By analyzing blood-based biomarkers, Dr Mason and team found disruptions in coagulation, oxidative stress, and brain-related proteins, with changes more pronounced in immune cells than red blood cells. These findings were detailed in the latest publication, “Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight”, which was a part of the Nature Press package of 45 publications.

OSDR recently spoke to Dr Mason to hear about the highlights and implications of this research, and about how the OSDR and AWGs enabled this publication.

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