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Latest News

Open Science Success Stories with Dr Keith Siew

Open Science Success Stories: Dr Keith Siew Welcome to our “Open Science Success Stories”. These narratives showcase insights gleaned from…

Meet the Authors – October 2024

“Meet the Authors”: Space Health Factors in Publications Enabled by Open Science Welcome to “Meet the Authors”, OSDR’s newest series…

GeneLab Chats with Gbolaga Olanrewaju on His Latest Publication

GeneLab Chats with Gbolaga Olanrewaju on His Latest Publication Welcome to “GeneLab Chats”, a series intended for succinct interviews with…

By the Numbers

NASA Open Science Data Repositories expands scientists’ access to space-related experiments that explore the biological response of terrestrial biology to spaceflight environments. Our mission is to maximize the utilization of the valuable biological research resources and enable new discoveries.

TODAY

509

Studies

973

Datasets

Publication Highlight

Aging and putative frailty biomarkers are altered by spaceflight

Human space exploration poses health risks that lead to molecular changes in astronauts, such as genomic instability, mitochondrial dysfunction, and increased inflammation, which are similar to aging-related shifts on Earth. Using murine and astronaut data from NASA’s GeneLab, JAXA, and Inspiration4 missions, researchers assessed biological markers associated with frailty, aging, and sarcopenia in space, revealing gene expression changes that may signal a frailty-like condition in astronauts. These findings suggest that spaceflight-induced changes may mirror those in aging, indicating the potential value of a frailty index for monitoring astronaut health.

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Image of the effects of spaceflight and a model of aging.

Visualization Tools

Data Visualization

GeneLab’s latest software release includes a new visualization portal to interact with gene expression data from space-related omics experiments. The enhanced portal includes a new search interface, new plots and layout, and advanced settings to customize the plots.

RadLab

RadLab is a portal that aims to provide a single point of access to radiation telemetry data from multiple databases maintained by multiple space agencies.

Environmental Data App (EDA)

The Environmental Data App (EDA) is a portal where users can visualize and compare ISS (International Space Station) cabin environmental telemetry data and radiation data gathered from spaceflight missions.

Testimonials

Sally Ha, GL4HS 2019 Cohort

“The GL4HS program gave me the skills and confidence to pursue an undergraduate degree in bioinformatics, and I hope that it continues to inspire students to reach for their highest potential!”

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Image of GeneLab for High Schools (GL4HS) alum, Sally Ha.

Open Science Projects

Open Science Projects primary goals aim to increase collaborative scientific data sharing, analysis, and more rapid scientific advancement.

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