Open Science Data Repository
The NASA Open Science Data Repository (OSDR) enables access to space-related data from experiments and missions that investigate biological and health responses of terrestrial life to spaceflight. The goal of OSDR is to enable multi-modal and multi-hierarchical fundamental space life science data be reused toward basic science, applied science, and operational outcomes for space exploration and knowledge discovery. These data include ‘omics, phenotypic, physiological, behavioral, hardware, environmental telemetry; raw, processed; tabular, text, code, bioimaging, and video.
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Latest News

New Educator Materials Available! Is this the semester you really want to try teaching something new, but still need to…

Open Science Success Stories: Alice Finkelstein and Angela Mo Welcome to our “Open Science Success Stories”. These narratives showcase insights…

OSDR Chats with Konstantinos Adamopoulos on His Latest Publication Welcome to OSDR Chats, an interview series featuring authors of OSDR-enabled…

By the Numbers
NASA Open Science Data Repositories expands scientists’ access to space-related experiments that explore the biological response of terrestrial biology to spaceflight environments. Our mission is to maximize the utilization of the valuable biological research resources and enable new discoveries.
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Studies
Datasets
Latest Datasets
Publication Highlight
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight
Spaceflight affects the immune system, causing changes in inflammation, aging, and muscle-related molecules. Researchers found a unique “spaceflight signature” in astronauts’ genes, showing increased activity in immune and stress-related pathways, which matched findings from other spaceflight studies. The study highlights immune disruptions and suggests ways to protect astronaut health on future missions.
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Visualization Tools

Data Visualization
GeneLab’s latest software release includes a new visualization portal to interact with gene expression data from space-related omics experiments. The enhanced portal includes a new search interface, new plots and layout, and advanced settings to customize the plots.

RadLab
RadLab is a portal that aims to provide a single point of access to radiation telemetry data from multiple databases maintained by multiple space agencies.

Environmental Data App (EDA)
The Environmental Data App (EDA) is a portal where users can visualize and compare ISS (International Space Station) cabin environmental telemetry data and radiation data gathered from spaceflight missions.
Testimonials
Dr Val Fajardo – Brock University
“This really is a great initiative. I’m proud to be a part of it. I’m proud to be a part of Open Science. It really does seem like the best way to move forward in terms of maximizing data usage and research exposure, and also to maintain the integrity of science.”
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Open Science Projects
Open Science Projects primary goals aim to increase collaborative scientific data sharing, analysis, and more rapid scientific advancement.