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ISS National Laboratory

Fostering scientific and technological innovation, advancing US leadership in commercial space, and inspiring the next generation.

The International Space Station photographed by Expedition 56 crew members from a Soyuz spacecraft after undocking. NASA astronauts Andrew Feustel and Ricky Arnold and Roscosmos cosmonaut Oleg Artemyev executed a fly around of the orbiting laboratory to take pictures of the station before returning home after spending 197 days in space. The station will celebrate the 20th anniversary of the launch of the first element Zarya in November 2018. Credit: NASA/Roscosmos

About ISS National Lab

In an effort to expand the research opportunities of this unparalleled platform, the ISS was designated as a U.S. National Laboratory in 2005 by Congress, enabling space research and development access to a broad range of commercial, academic, and government users. 

What a Spacefaring Arctic Microbe Reveals About Life in Alien Oceans

Colwellia psychrerythraea is, as organisms go, almost aggressively hard to kill. Which makes what happened to it onboard the International Space Station (ISS) in 2025 genuinely strange. The bacterium had everything it needed, afloat in nutrient-rich water at a temperature it could tolerate. Yet for weeks, it acted as if it were paralyzed and starving to death.

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NASA astronaut and Expedition 73 Flight Engineer Anne McClain works in the Kibo laboratory module's Life Sciences Glovebox processing bacteria samples before viewing them inside a 3D imaging microscope called the Extant Life Volumetric Imaging System, or ELVIS. The technology demonstration may enable applications for monitoring water quality, detecting infectious organisms on spacecraft, and researching colloids (suspensions of particles in a liquid) and microorganisms in microgravity.
iss073e0027808 (May 10, 2025) — NASA astronaut and Expedition 73 Flight Engineer Anne McClain works in the Kibo laboratory module’s Life Sciences Glovebox processing bacteria samples before viewing them inside a 3D imaging microscope called the Extant Life Volumetric Imaging System, or ELVIS. The technology demonstration may enable applications for monitoring water quality, detecting infectious organisms on spacecraft, and researching colloids (suspensions of particles in a liquid) and microorganisms in microgravity.
NASA

An Unexpected Space Discovery May Improve Vaccines for Older Adults

For a team of researchers at the global pharmaceutical company Sanofi, unexpected findings from research on the International Space Station (ISS) may help scientists develop more effective vaccines, particularly in a key population: older adults.

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iss065e026996 (5/8/2021) — NASA astronaut Megan McArthur services donor cells inside the Kibo laboratory module’s Life Science Glovebox for the Celestial Immunity study. The human research investigation may provide insights into new vaccines and drugs possibly advancing the commercialization of space.