iss051e036121 (May 3, 2017) — An over-the-shoulder look at Commander Peggy Whitson working inside the Microgravity Sciences Glovebox (MSG) to change the media in the BioCell for the OsteoOmics experiment. Image was taken in the Destiny U.S. Laboratory. Gravitational Regulation of Osteoblast Genomics and Metabolism (OsteoOmics) aims to validate if magnetic levitation is a reasonable simulation of orbital free fall by measuring biological endpoints, such as signaling pathways and gene expression in osteoblast and osteoclast cells. Cells are exposed to a microgravity environment and ground based cells are exposed to magnetic levitation. If the validation is successful, then ground-based magnetic levitation will be an important ground-based tool to investigate the effect of gravitational force on biological systems.