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Human Health Countermeasures

The Human Health Countermeasures (HHC) element of NASA’s Human Research Program (HRP) seeks to understand the physiological effects of spaceflight and develop strategies to mitigate those with detrimental effects on human health and performance.

NASA astronaut Anne McClain exercises in the Node 3 module.

Spaceflight Risks

The Human Health Countermeasures group is situated within the Human Research Program. Its research helps to ensure the health and safety of astronauts by tackling the spaceflight risks described below.

Astronaut gives himself immunization

Risk of Altered Immune System Responses

The stresses of spaceflight can awaken inactive viruses inside the bodies of astronauts, leading to rashes and other symptoms. Ongoing work seeks to further understand changes in the immune system to better protect astronaut health.

cipher argos

Risk of Altered Sensorimotor and Vestibular Function

Astronauts can experience motion sickness, issues with hand-eye or gait coordination, and dizziness during gravitational changes, making it difficult to walk or operate a vehicle. Ongoing research seeks to help astronauts recover faster from these changes so they can perform tasks inside and outside spacecraft.

Ultrasound-2 device

Risk of Cardiovascular Adaptations

Weightlessness alters blood circulation and how the heart and blood vessels function, potentially increasing the risk of cardiovascular events. Research focuses on minimizing these unhealthy changes.

Risk of Decompression Sickness

Transitioning from a pressurized spacecraft to a lower-pressure spacesuit can cause health and mission complications when dissolved nitrogen starts to bubble within body tissues. Research focuses on developing better prevention and faster treatment options.

Petri dishes

Risk of Host-Microorganism Interactions

Skin and gut microbiomes can change in space, potentially increasing the risk of crew members getting sick. To help keep crews healthy, researchers are exploring these microbial ecosystems and how they evolve in space.

Risk of Hypoxia

Astronauts on future deep space missions will take steps to avoid “the bends” during spacewalks through an approach that elevates the risk of mild hypoxia — a condition that occurs when oxygen levels in body tissues become lower than normal. Research focuses on defining safe oxygen thresholds, monitoring astronaut health, and treating astronauts who experience mild hypoxia.

Oranges

Risk of Inadequate Food and Nutrition

A healthy, balanced diet is an essential element of crew health and performance. Ongoing research focuses on designing enjoyable, long-lasting, and nutritious meals for deep space missions and understanding the consequences of inadequate nutrition.

Risk of Injury and Compromised Performance from Spacewalks

Working in a spacesuit is challenging. In addition to cognitive fatigue and injury, crew members must also manage risks in the spacewalk environment, including decompression sickness, and low oxygen and high carbon dioxide levels. Research focuses on characterizing human performance in spacesuits and balancing pressure and oxygen levels.

Furukawa wears a black t-shirt and shorts and tennis shoes. His feet are on a black panel and he is squatting, holding on to a silver bar behind his shoulders. The bar is attached to blue metal poles on either side of him.

Risk of Reduced Cardiorespiratory and Musculoskeletal Fitness

All astronauts perform exercise during their mission to counteract losses in bone density, muscle strength, and heart and blood vessel performance. Researchers are studying what types of exercise will best protect their health and their ability to perform spacewalks.

Visual Impairment Intracranial Pressure (VIIP) Syndrome was identified in 2005. It is currently NASA’s leading spaceflight-related health risk, and is more predominant among men than women in space. Here, NASA astronaut Karen Nyberg of NASA uses a fundoscope to image her eye while in orbit.

Risk of Spaceflight Associated Neuro-ocular Syndrome (SANS)

The structure of the eyes and brain can change with spaceflight.  Research focuses on understanding the long-term health consequences of these changes and preventing them from occurring. 

Risk of Spaceflight-Induced Bone Changes

Without gravity, bones break down and become more brittle, boosting the chances of painful breaks. Ongoing research seeks to better understand and quantify these losses, and help preserve bone strength through diet, exercise, and medication.