Fathi Karouia

Affiliation: Blue Marble Space Institute of Science

Division: Space Science and Astrobiology

Branch: Exobiology

Email: fathi.karouia@nasa.gov

Phone: (650)-604-6589

Personal Websites: https://www.spacerewire.com/

Read Fathi Karouia’s interview

Professional Biography

Principal Positions Held

Research Faculty (Bioastronautics/BioServe), Ann and H.J. Smead Aerospace Engineering Science, University of Colorado Boulder, 2023-present.

Senior Research Scientist, Blue Marble Space Institute of Science, Exobiology Branch, NASA Ames Research Center, 2019-present.

Research Professor, Dept. of Pharmaceutical Chemistry, University of California San Francisco, 2013-2019.

Assistant Research Professor, Dept. of Pharmaceutical Chemistry, University of California San Francisco, 2011-2013.

NASA Postdoctoral Fellow, Oak Ridge Associated Universities, Exobiology Branch, NASA Ames Research Center, 2009-2011

ISSO Postdoctoral Fellow, Institute of Space System Operations, University of Houston, 2008-2009.

Research Associate, Space Life Sciences, NSA Johnson Space Center, 2000-2003.

Research Associate, Strategy Quality, Centre National d’Etudes Spatiales (CNES), 1999

Other Positions Held Concurrently

Co-Chair, the Advancements in Astrobiology and Space Exploration, International Astronautical Federation, 2023-present.

Co-Chair, In Space Manufacturing and Production Applications, International Astronautical Federation, 2023-present.

Governing Board Member, American Society of Gravitational and Space Research, 2023-present.

In-Space Commercialization Lead, BioServe Technologies, University of Colorado Boulder, 2023-present.

Co-founder, Elastic Linear Algebra Builders for Space (ELAB4SPACE), 2022-present.

Founder, Space Research Within Reach, 2019-present.

Consultant, European Science Foundation, 2019-present.

Senior Research Scientist, Exobiology Branch, NASA Ames Research Center, 2011-2019.

Non-Rodent Portfolio Lead Scientist, Space Biology Program, NASA Ames Research Center, 2015-2019.

Project Scientist, Space Biology Program, NASA Ames Research Center, 2013-2019.

Research Assistant, Dept. of Radiation Oncology, University of Texas Medical Branch, 2000-2001.

Education

Ph.D in Biology (Cell and Molecular Biology), University of Houston (USA).

Master of Space Studies, International Space University (France).

Master of Science, Applied Space Technologies, Strasbourg University (Louis Pasteur University, France).

Master of Science, Physics (Plasma), Henri Poincare University (France).

Bachelor of Science, Physics and Chemistry, Henri Poincare University (France).

Research Interests

I take a systemic, systems-level approach to understand how spaceflight and its analogs (simulated microgravity and space radiation) reshape biology—from molecules to tissues and whole organisms—in service of astronaut health, planetary protection, and in-space biomanufacturing. I pair open-data science (e.g., NASA GeneLab) with flight and ground studies to discover biomarkers, validate countermeasures, and build in-situ analytical capabilities for space.

• Scope: Astrobiology, planetary protection, space biology, astronaut health & performance, in-space manufacturing, and exploration-enabling technologies.
• Core question: How do microgravity and radiation drive molecular network changes that scale to cellular function, tissue/organ physiology, organismal phenotypes, and mission performance?
• Experimental platforms: Simulated microgravity (clinostats/RWV, RPM) and radiation (proton/ion/GCR simulators), plus suborbital/orbital missions including human and model-organism studies flown on the ISS.
• Models & scales: Microbes → human/mammalian cells → organoids/organ-on-chips → small animals → astronauts; integration across molecular, cellular, tissue/organ, and whole-body levels.
• Methods: Multi-omics (genomic/epigenomic/transcriptomic/proteomic/metabolomic), single-cell and spatial profiling, advanced imaging/biomechanics, and causal/integrative modeling to link mechanisms with phenotypes.
• Open science: Leverage open-access platforms such as NASA GeneLab to generate/test hypotheses, harmonize datasets, reproduce findings, and accelerate countermeasure discovery with transparent, shareable workflows.
• Countermeasures: Design and validate interventions (biologics, small molecules, nutritional/microbiome, operational protocols) with endpoints tied to resilience, performance, and long-term health.
• In-situ analytics: Pioneer miniaturized, automated, radiation-tolerant microfluidics and lab-on-chip payloads for on-orbit sample handling and readouts (including omics/phenotyping), with AI/edge processing to enable adaptive experiments in space.
• Planetary protection: Quantify microbial survival, adaptation, and dispersal; develop low-biomass detection, sterilization, and biosecurity workflows to prevent forward/back contamination while safeguarding science return.
• In-space biomanufacturing: Exploit microgravity-enabled processes (e.g., cell expansion, advanced bioprocessing, crystallization/structuring) to produce high-value biomedical products and mission consumables, translating outcomes back to Earth.

Selected Publications

Genomic characterization of Microbacterium meirae sp. nov., a novel bacterium isolated from the international Space Station. F Karouia, L. C. de Oliveira, A. Hameed, A. Simpson, N Singh, P D. Rekha, C. Mason, and K. Venkateswaran. Scientific Reports 2025. doi/10.1038/s41598-025-13974-5.C: N/A; IF: 3.9.

In Memoriam: Professor Andrez (Andrew) Pohorille (May 14, 1949, to January 6, 2024): A Legacy in Astrobiology and Computational Science. F Karouia, M Wilson, K Schweighofer, T Hoehler, and J Sokolowska. Astrobiology Vol 25, 7, 2025. C: N/A; IF: 2.6.

A Novel In Situ Green Method for Synthesizing a Palladium Nos-based Catalyst Aimed at the Selective Hydrogenation of Aldehydes in Cinnamaldehyde. A. Mehri, H. Touati, K. Kaaroud, F. Karouia, M.H.V. Baouab. Colloids and Surfaces A: Physicochemical and Engineering Aspects. Vol 719,137035, 2025.

The International Space Station has a unique and extreme microbial and chemical environment driven by use patterns. Rodolfo A Salido, Haoqi Nina Zhao, Daniel McDonald, Helena Mannochio-Russo, Simone Zuffa, Renee E Oles, Allegra T Aron, Yasin El Abiead, Sawyer Farmer, Antonio González, Cameron Martino, Ipsita Mohanty, Ceth W Parker, Lucas Patel, Paulo Wender Portal Gomes, Robin Schmid, Tara Schwartz, Jennifer Zhu, Michael R Barratt, Kathleen H Rubins, Hiutung Chu, Fathi Karouia, Kasthuri Venkateswaran, Pieter C Dorrestein, Rob Knight. Cell. 2025 Feb 27^th. C:N/A; IF: 45.5

Spaceflight Alters Host-Gut Microbiota Interactions. E. Gonzalez, MD Lee, BT Tierney, N Lipieta, P Flores, Maya Mishra, Laura Beckett, Fathi Karouia, Richard Barker, Rick Jansen, Stefan Green, Silvio Weging, Jared T Broddrick, Nitin K Singh, Daniela Bezdan, Jonathan Matthew Galazka, Nicholas JB Brereton. NPJ Biofilms Microbiomes. 2024 Aug 29;10(1):71. C:N/A; IF: N/A

The Second Space Age: Omics, Platforms, and Medicine Across Orbits. Christopher E. Mason, James Green, Konstantinos I. Adamopoulos, Evan E. Afshin, Jordan J. Baechie, Mathias Basner, Susan M Bailey, Luca Bielski, Josef Borg, Joseph Borg, Jared T Broddrick, Marissa Burke, Andrés Caicedo, Verónica Castañeda, Subhamoy Chatterjee, Christopher R Chin, George Church, Sylvain V Costes, Iwijn De Vlaminck, Rajeev I Desai, Raja Dhir, Juan Esteban Diaz, Sofia M Etlin, Zachary Feinstein, David Furman, J Sebastian Garcia-Medina, Francine Garrett-Bakelman, Stefania Giacomello, Anjali Gupta, Amira Hassanin, Nadia Houerbi, Iris Irby, Emilia Javorsky, Peter Jirak, Christopher W Jones, Khaled Y Kamal, Brian D Kangas, Fathi Karouia, JangKeun Kim, Joo Hyun Kim, Ashley S Kleinman, Try Lam, John M Lawler, Jessica A Lee, Charles L Limoli, Alexander Lucaci, Matthew MacKay, J Tyson McDonald, Ari M Melnick, Cem Meydan, Jakub Mieczkowski, Masafumi Muratani, Deena Najjar, Mariam A Othman, Eliah G Overbey, Vera Paar, Jiwoon Park, Amber M Paul, Adrian Perdyan, Jacqueline Proszynski, Robert J Reynolds, April E Ronca, Kate Rubins, Krista A Ryon, Lauren M Sanders, Patricia Savi Glowe, Yash Shevde, Michael A Schmidt, Ryan T Scott, Bader Shirah, Karolina Sienkiewicz, Maria A Sierra, Keith Siew, Corey A Theriot, Braden T Tierney, Kasthuri Venkateswaran, Jeremy Wain Hirschberg, Stephen B Walsh, Claire Walter, Daniel A Winer, Min Yu, Luis Zea, Jaime Mateus, Afshin Beheshti. Nature. 2024 Aug: 632 (8027): 995-1008. C:27; IF: 64.8

Cosmic Kidney Disease: The Effects of Spaceflight and Galactic Cosmic Radiation on Renal Structure and Function. Keith Siew, Kevin A Nestler, Charlotte Nelson, Viola D’Ambrosio, Chutong Zhong, Zhongwang Li, Alessandra Grillo, Elizabeth R Wan, Vaksha Patel, Eliah Overbey, JangKeun Kim, Sanghee Yun, Michael B Vaughan, Chris Cheshire, Laura Cubitt, Jessica Broni-Tabi, Maneera Yousef Al-Jaber, Valery Boyko, Cem Meydan, Peter Barker, Shehbeel Arif, Fatemeh Afsari, Noah Allen, Mohammed Al-Maadheed, Selin Altinok, Nourdine Bah, Samuel Border, Amanda L Brown, Keith Burling, Margareth Cheng-Campbell, Lorianna M Colón, Lovorka Degoricija, Nichola Figg, Rebecca Finch, Jonathan Foox, Pouya Faridi, Alison French, Samrawit Gebre, Peter Gordon, Nadia Houerbi, Hossein Valipour Kahrood, Frederico C Kiffer, Aleksandra S Klosinska, Angela Kubik, Han-Chung Lee, Yinghui Li, Nicholas Lucarelli, Anthony L Marullo, Irina Matei, Colleen M McCann, Sayat Mimar, Ahmed Naglah, Jérôme Nicod, Kevin M O’Shaughnessy, Lorraine Christine De Oliveira, Leah Oswalt, Laura Ioana Patras, San-huei Lai Polo, María Rodríguez-Lopez, Candice Roufosse, Omid Sadeghi-Alavijeh, Rebekah Sanchez-Hodge, Anindya S Paul, Ralf Bernd Schittenhelm, Annalise Schweickart, Ryan T Scott, Terry Chin Choy Lim Kam Sian, Willian A da Silveira, Hubert Slawinski, Daniel Snell, Julio Sosa, Amanda M Saravia-Butler, Marshall Tabetah, Erwin Tanuwidjaya, Simon Walker-Samuel, Xiaoping Yang, Yasmin, Haijian Zhang, Jasminka Godovac-Zimmermann, Pinaki Sarder, Lauren M Sanders, Sylvain V Costes, Robert AA Campbell, Fathi Karouia, Vidya Mohamed-Alis, Samuel Rodriques, Steven Lynham, Joel Ricky Steele, Sergio Baranzini, Hossein Fazelinia, Zhongquan Dai, Akira Uruno, Dai Shiba, Masayuki Yamamoto, Eduardo AC Almeida, Elizabeth Blaber, Jonathan C Schisler, Amelia J Eisch, Masafumi Muratani, Sara R Zwart, Scott M Smith, Jonathan M Galazka, Christopher E Mason, Afshin Beheshti, Stephen B WalshS. Walsh, K Siew, et al., Nature Communications. 2024 Jun 11:15(1):4923. C:26; IF: 17.69

Ethical Considerations for the Age of non-Governmental Space Exploration. Allen Seylani, Aman Singh Galsinh, Alexia Tasoula, Anu R I, Andrea Camera, Jean Calleja-Agius, Joseph Borg, Chirag Goel, JangKeun Kim, Kevin B. Clark, Saswati Das, Shehbeel Arif, Michael Boerrigter, Caroline Coffey, Nathaniel Szewczyk, Christopher E. Mason, Fathi Karouia, Hansjörg Schwertz, Afshin Beheshti, Dana Tulodziecki. Nature Communications. 2024 Jun 11;15(1)4774. C:7; IF: 17.69

Aging and Putative Frailty Biomarkers Are Altered by Spaceflight. Andrea Camera, Marshall Tabetah, Veronica Castaneda, JangKeun Kim, Aman Singh Galsinh, Alissen Haro-Vinueza, Ivonne Salinas, Allen Seylani, Shehbeel Arif, Saswati Das, Marcelo Mori, Antonio Carano, Lorraine Christine De Oloveira, Masafumi Muratani, Richard Baker, Victoria Zaksas, Chirag Goel, Eleni Dimokidis, Deanne M. Taylor, Jisu Jeong, Eliah Overbey, Cem Meydan, D. Marshall Porterfield, Juan Esteban Díaz, Andrés Caicedo, Jonathan C. Schisler, Evagelia C. Laiakis, Christopher E. Mason, Man S Kim, Fathi Karouia, Nathaniel J Szewczyk, Afshin Beheshti. Scientific Reports 2024 Jun 11;14(1):13098. C:N/A; IF: 4.97

Spaceflight induces changes in gene expression profiles linked to insulin and estrogen Insulin and Estrogen. Begum Aydogan Mathyk, Marshall Tabetah, Rashid Karim, Victoria Zaksas, JangKeun Kim, Anu R I, Masafumi Muratani, Alexia Tasoula, Ruth Subhash Singh, Yen-Kai Chen, Eliah Overbey, Jiwoon Park, Davide Povero, Joseph Borg, Remi V Klotz, Min Yu, Steven L Young, Christopher E. Mason, Nathaniel Szewczyk, Riley M. St Clair, Fathi Karouia, Afshin Beheshti. Communications Biology 2024 Jun 11;7(1):692. C:N/A; IF: 6.54

Understanding How Space Travel Affects the Female Reproductive System. Begum Aydogan Mathyk, Alexander M Quaas, Cihan Halicigil, Fathi Karouia, Michael Strug, Brent Monseur, Murat Basar, Steven L Young, Savas Tasoglu, Afshin Beheshti. NPJ Women’s Health 2024 2(1), 20. C:N/A; IF: N/A.

Planetary Protection Knowledge Gap Closure Enabling Crewed Missions to Mars. James A. Spry, Bette Siegel, Corien U. Bakermans, David W. Beaty, Mary-Sue Bell, James N. Benardini, Rosalba Bonaccorsi, Sarah L. Castro-Wallace, David Coil, Athena Coustenis, Peter Doran, Lori Fenton, David P. Fidler, Matthew Fields, Brian Glass, Stephen J. Hoffman, Fathi Karouia, Michael J. Kempf, Joel S. Levine, Robert Lindberg, Mark L. Lupisella, Javier Martin-Torres, Rakesh Mogul, Karen Olsson-Francis, Manish Patel, David Pearce, Margaret Race, Aaron B. Regberg, Petra Rettberg, Robert R. Zimmerman, Kathleen Rubins, Ondre Santolik, Kevin Y. Sato, Andrew Schuerger, Elliot Sefton-Nash, Matthew Sharkey, Nitin K. Singh, Silvio Sinibaldi, Perry Stabekis, Carol R. Stoker, Kasthuri J. Venkateswaran, Maria-Paz Zorzano-Mier. Astrobiology. 2024 Mar;24(3):230-274

Assessing microbial diversity in Yellowstone National Park hot springs using deployable automated nucleic acid extraction system. JM. Wood, Camilla Urbaniak, Ceth Parker, Nitin Singh, Season Wong, Arun Kumar, Dana Skorupa, Ashlyn Hemmah, Phoebe Laaguiby, Fathi Karouia, Brent Peyton, Scott Tighe, Kasthuri Venkateswaran. Front. Ecol. Evol., 12:1306008, 2024. C:N/A; IF:3.0

Genomic characterization and radiation tolerance of Naganishia kalamii sp. nov. and Cystobasidium onofrii sp. nov. from Mars 2020 mission assembly facilities. P. Leo,  M.de Melo Texeira, A. M. Cahnder, N. K. Singh, A, C. Simpson, A. Yurkov, F. Karouia, J. E. Stajch, C. E. Mason, K. Venkateswaran. IMA Fungus 2023. C:N/A; IF: 5.4

Comparative genomic analysis of Cohnella hashimotonis sp. nov. isolated from the International Space Station. A. C. Simpson, v. V. Ramprasad Eedara, N. K. Singh, Namita Danle,  F. Karouia, C. E. Mason, K. Venkateswaran. Front Microbiol. 2023 Jun 15;14:1166013. C:N/A; IF: 5.2

Beneficial effect of in-situ citrate-grafting of hydroxyapatite surface for water treatment. D Bouazzi, A Mehri, K Kaaroud, H Touati, F Karouia, JM Clacens, A Laghzizil, B Badraoui. Colloids and Surfaces A: Physicochemical and Engineering Aspects; Vol 666, 5 June 2023, 131366. C:1; IF: 5.2

Lab Medicine in Space, J R. Wiencek, S. Das, A. Beheshti, B E. Crucian, F. Karouia et al., Clinical Chemistry, Vol 69, issue 5, 2023, p442-449. C:N/A; IF: 9.3

Extraterrestrial Gynecology: Could Spaceflight Increase the Risk of Developing Cancer in Female Astronauts? An Updated Review. R. Drago-Ferrante, R. Di Fiore, F Karouia, Y. Subbannayya, S. Das, B. M. Mathyk, S Arif, A. P. Guevara-Cerdan, A Seylani, A. S. Galsinh, V. Kukulska, J. Borg, S. Suleiman, D. M. Porterfield, A. Camera, L.K. Christenson, A. E. Ronca, J.G. Steller, A. Beheshti, and J. Calleja-Agius. Int J Mol Sci. 2022 Jul 5:23 (13): 7465 C:25; IF: 5.6

Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station. Camilla Urbaniak; Michael D. Morrison; James B. Thissen; Fathi Karouia; David J. Smith; Satish Mehta; Crystal Jaing; Kasthuri Venkateswaran. Microbiome. 2022 Jun 29; 10(1): 100. C:15;  IF: 15.5

Low-Temperature O₃ Decomposition over Pd-TiO₂ Hybrid Catalysts. Touati H, Mehri A, Karouia F, Richard F, Batiot-Dupeyrat, Daniele S, Clacens JM. Catalysts 2022, 12 (4), 488. C:3; IF: 3.9

Investigation of Spaceflight Induced Changes to Astronaut Microbiomes. M. D. Morrison; J. B. Thissen; C. Urbaniak; F. Karouia; S. Mehta; K. Venkateswaran; D. J. Smith; and C. Jaing. Front. Microbiol., 2 Jun 2021, 12:1368. C:29; IF: 5.2

Human Neural Stem Cells Proliferate More in Space, Have a Shorter Cell Cycle, and are Larger than Ground Control Cells After Space Flight: Implications for Long-term Space Travel. Sophia Shaka,Nicholas Carpo, Victoria Tran, Fathi Karouia, and Araceli Espinosa-Jeffrey. J Stem Cells Res Dev. 2021, 7:069. C:5; IF: 4

Assessing the risk of transfer of microorganisms at the International Space Station owing to cargo delivery by commercial resupply vehicles. Snehit Satish Mhatre; Jason Wood; Aleksandra Checinska Sielaff; Mora Maximilian; Stefanie Duller; Nitin kumar Singh; Fathi Karouia; Christine Moissl Eichinger; Kasthuri Venkateswaran. Front. Microbiol., 6 Nov 2020; Vol 11. C:12; IF: 5.2

Draft Genome Sequences of Lactobacillales Isolated from the International Space Station. Bharadwaj AR, Singh NK, Wood JM, Debieu M, O’Hara NB,Karouia F, Mason CE, Venkateswaran K. Microbiol Resour Announc. 2020 Sep 24; 9(39). C:2; IF: 0.58

Draft Genome Sequences of Enterobacteriales Strains Isolated from the International Space Station. Bharadwaj AR, Daudu R, Singh NK, Wood JM, Debieu M, O’Hara NB,Karouia F, Mason CE, Venkateswaran K. Microbiol Resour Announc. 2020 Sep 10; 9(37). C:2; IF: 0.58

Validating an automated nucleic acid extraction device for omics in space using whole cell microbial reference standards. Camilla Urbaniak; Season Wong; Scott Tighe; Arun Kumar; Bo Liu; Ceth Parker; Jason Wood; Nitin Singh; Dana Skorupa; Brent Peyton; Ryan Jenson; Fathi Karouia; Julie Dragon; Kasthuri Venkateswaran. July 2020; Frontiers in Microbiology 11:1909. C:10; IF: 5.2

Crewmember microbiota may influence taxonomy of ISS habitable surface metagenomes. Aram Avila-Herrera; James Thissen; Camilla Urbaniak; Nicholas A. Be; David J. Smith; Fathi Karouia; Satish Mehta; Kasthuri Venkateswaran; Crystal Jaing. PLoS One. 2020 Apr 29;15(4). C:53; IF: 3.7

Human Neural Stem Cells Flown into Space Proliferate and Generate Young Neurons. Carlos Cepeda, Laurent Vergnes, Nicholas Carpo, Matthew Schibler, Laurent Bentolila, Fathi Karouia, and Araceli Espinosa-Jeffrey. Appl. Sci. 2019, 9 (19), 4042. C:6; IF: 2.7

Gene Expression Measurement Module (GEMM) for space application: Design and validation. Peyvan K, Karouia F, Cooper JJ, Chamberlain J, Suciu D, Slota M, and Pohorille A. Life Sci Space Res. 2019 Aug;22:55-67. C:5; IF: 2.73

Characterization of the Total and Viable bacterial and fungal communities associated with the International Space Station Surfaces. Aleksandra Checinska Sielaff; Camilla Urbaniak; Ganesh Babu Malli Mohan; Victor G. Stepanov; Quyen Tran; Wood JM; Minich J; McDonald D; Mayer T; Knight R; Fathi Karouia; George E. Fox; Kasthuri Venkateswaran. Microbiome. 2019 Apr 8;7(1): 50. C:173; IF: 15.5

Evaluation of Acquired Antibiotic Resistance in Escherichia coli Exposed to Long-Term Low-Shear Modeled Microgravity and Background Antibiotic Exposure. Madhan Tirumalai, Fathi Karouia, Quyen Tran, Victor G. Stepanov, Rebekah Bruce, C. Mark Ott, Duane Pierson, and George Fox. MBio. 2019 Jan 15; 10(1). C:40; IF: 7.78

International Space Station conditions alter genomics, proteomics, and metabolomics in Aspergillus Nidulans.Jillian Romsdahl, Adriana Blachowicz, Abby Chiang, Yi-Ming Chiang, Junko Yaegashi, Stefanie Countryman, Fathi Karouia, Markus Kalkum, Jason E. Stajich, Kasthuri Venkateswaran, and Clay C.C. Wang. Appl Microbiol Biotechnol. 2019 Feb; 103(3):1363-1377. C:29; IF: 5.56

Succession and persistence of microbial communities and antibiotic resistance genes associated with International Space Station environmental surfaces. Nitin Singh, Jason Wood, Fathi Karouia, and Kasthuri Venkateswaran. Microbiome. 2018 Nov 13; 6(1): 204. C:123; IF: 15.5

Toward Biotechnology in Space: High-throughput Instruments for in situ biological Research beyond Earth. Karouia F, Peyvan K, and Pohorille A. Biotechnol Adv. 2017 Nov 15;35(7):905-32. C:54; IF: 16

Microbial Characteristics of the International Space Station Environmental Surfaces. Kasthuri Venkateswaran, Aleksandra Checinska, Nitin Singh, Ganesh B. M. Mohan, Camilla Urbaniak, Adriana Blachowicz, George E. Fox, Crystal Jaing, Jonathan E. Allen, Kenneth Frey, David Smith, Satish Mehta, Nicholas H. Bergman, Fathi Karouia, Clay Wang, Nancy Keller, Duane L. Pierson, and Jay Perry. ICES-2017-131. C:8; IF: 3.26

The Adaptation of E. coli Cells Grown in Simulated Microgravity for an Extended Period is Both Environmental and Genomic. Madhan Tirumalai, Fathi Karouia , Quyen Tran, C. Mark Ott, Duane Pierson, Rebekah Bruce, and George Fox. NPJ Microgravity. 2017 May 23;3:15. C:33; IF: 4.97

Cellular Responses and Gene Expression Profile Changes due to Bleomycin-Induced DNA Damage in Human Fibroblasts in Space. Honglu Wu; Tao Lu; Ye Zhang; Yared Kidane; Alan Feiveson; Louis Stodieck; Fathi Karouia; Govindarajan Ramesh; and Larry Rohde. PLoS One. 2017 Mar 1;12(3). C:32; IF: 3.7

Detection of DNA damage by space radiation in human fibroblasts flown on the International Space Station. Tao Lu, Ye Zhang, Michael Wong, Alan Feiveson, Ramona Gaza, Nicholas Stoffle, Huichen Wang, Bobby Wilson, Larry Rohde, Luis Stodieck, Fathi Karouia, and Honglu Wu. Life Sci Space Res. Volume 12, Feb 2017, P24-31. C:44; IF: 2.73

Transient gene and miRNA expression profile changes of confluent human fibroblast cells in space. Ye Zhang, Tao Lu, Michael Wong, Xiaoyu Wang, Louis Stodieck, Fathi Karouia, Michael Story, Honglu Wu. FASEB J. 2016 Jun;30(6):2211-24. C:31; IF: 5.834

Microorganisms, organic carbon and oxidant activity interactions in hyper-arid Mars-like soils: Implications in soil habitability. Julio E. Valdivia-Silva, Fathi Karouia, Rafael Navarro-González, and Christopher McKay. PALAIOS, 2016, V. 30, 1-9. C:10; IF: 1.60

GEMM: An Automated Instrument for in-situ Gene Expression Measurements on Board the International Space Station. F Karouia, K Peyvan, D Bajorins, LS Stodieck, AJ Ricco, O Santos, and A Pohorille. Results and Opportunities-The Decade of Utilization, Vol. 114, Science and Technology Series, American Astronautical Society, 2013, pp141-142, ISBN 978-0-87703-594-7. C:N/A; IF: N/A

Long-term exposure of bacterial cells to simulated microgravity,Karouia F, Tirumalai MR, Nelman-Gonzalez MA, Sams CF, Ott MC, Pierson DL, Willson RC, Fofanov Y, and Fox GE. Proc. SPIE Vol 8521, Instruments, Methods, and Missions for Astrobiology XV, 85210K 1-6, 2012. C:3; IF: 1.13

Long-term Effects of Simulated Microgravity on Microbial Gene Expression. Tirumalai MR, Karouia F, Stepanov V, Tran Q, Pierson D and Fox GE. ISSO V09, pp178-180, 2011. C:3; IF: N/A

Martian Soil Biosensors Based on Dielectric Spectroscopy. John H. Miller, Jie Fang, David Warnflash, David S. McKay, Jeffrey A. Jones, and Fathi Karouia. ISSO V07, pp61-66, 2008. C:2; IF: N/A

Simulated Microgravity on Microbial Gene Expression. Fox GE, Willson RC, Pierson DL, Tirumalai MT, and Karouia F. ISSO V07, pp58-60, 2008. C:2; IF: N/A

Paradoxical DNA Repair and Peroxide Resistance Gene Conservation in Bacillus pumilus SAFR-032.Jason Gioia Madhan R Tirumalai, Shailaja Yerrapragada, Madhan R Tirumalai, Indrani Dasgupta, Lina Bokhetache, Yamei Liu, Prahathees E. Moorthy, Brian Davis McWilliams, Adeola A Olowu, Johnathan Siefert, Fathi Karouia, Kenneth D. Clinkenbeard, Avani Verma, Prince Buzumbo, Hiba Zwiya, Okezie Igboeli, Akif Uzman, Xiang Qin, Huaiyang Jiang, Sarah Highlander, Kasthuri Venkateswaran, George E Fox, George Weinstock. PLoS ONE. 2007 Sep 26;2(9):e928. C:155; IF: 3.7

Biosensors Based on Dielectric Spectroscopy, John H. Miller, Jaroslaw Wosik, David S. McKay, Jeffrey A. Jones, Fathi Karouia, David Warnflash, Dharmakeerthi Nawarathna, ISSO V05, pp33-38, 2006. C:2; IF: N/A.

A multi-goal Mars analogue expedition (expedition two) to the Arkaroola region, Australia. Jonathan DA Clarke, Rocky Persaud, Shannon Rupert, M Bishop, A Brown, A Clarke, JP Clarke, R Clarke, N Cutler, S Dawson, K Fitzsimmons, V Gostin, J Heldmann, S Jordan, F Karouia, P Krins, E Martinez, V Matic, G Murphy, A Rupert, N Stansfield, M Tanner, M Thomas, V Waclawik, J Waldie, D Willson. Mars Analog Research, Vol. 111, Science and Technology Series, American Astronautical Society, 2006, pp3-15, ISBN -87703-529-6. C:5; IF: N/A

PR or Perish? Promotion and Outreach Opportunities in Mars Analogue Research, Jennifer H. Laing, Reyna Jenkyns, and Fathi Karouia, Mars Analog Research, Vol. 111, Science and Technology Series, American Astronautical Society, 2006, pp39-52, ISBN -87703-529-6. C:2; IF:N/A

Effect of an artificial RNA marker on gene expression in Escherichia coli, Tucker DL, Karouia F, Wang J, Luo Y, Li TB, Willson RC, Fofanov Y, Fox GE: Applied Environmental Microbiology, 2005 july, 71(7):4156-9. C:7; IF:4.79

Characterization of Evolving Bacterial Populations, G. E. Fox, M. Travisano, R. Goldman, and F. Karouia, ISSO V02, pp85-86, 2003. C:2; IF:N/A

Review Articles

Understanding How Space Travel Affects the Female Reproductive System to the Moon and Beyond. Begum Aydogan Mathyk, Alexander M Quaas, Cihan Halicigil, Fathi Karouia, Michael Strug, Brent Monseur, Murat Basar, Steven L Young, Savas Tasoglu, Afshin Beheshti (Submitted to NPJ Microgravity). C:N/A; IF: 4.97

Lab Medicine in Space, J R. Wiencek, S. Das, A. Beheshti, B E. Crucian, F. Karouia et al., Clinical Chemistry, Vol 69, issue 5, 2023, p442-449. C:N/A; IF: 9.3

Extraterrestrial Gynecology: Could Spaceflight Increase the Risk of Developing Cancer in Female Astronauts? An Updated Review. R. Drago-Ferrante, R. Di Fiore, F Karouia, Y. Subbannayya, S. Das, B. M. Mathyk, S Arif, A. P. Guevara-Cerdan, A Seylani, A. S. Galsinh, V. Kukulska, J. Borg, S. Suleiman, D. M. Porterfield, A. Camera, L.K. Christenson, A. E. Ronca, J.G. Steller, A. Beheshti, and J. Calleja-Agius. Int J Mol Sci. 2022 Jul 5:23 (13): 7465 C:25; IF: 5.6

Toward Biotechnology in Space: High-throughput Instruments for in situ biological Research beyond Earth. Karouia F, Peyvan K, and Pohorille A. Biotechnol Adv. 2017 Nov 15;35(7):905-32. C:47; IF:14.23.

Books & Chapters

Genomic characterization of Microbacterium meirae sp. nov., a novel bacterium isolated from the international Space Station. F Karouia, L. C. de Oliveira, A. Hameed, A. Simpson, N Singh, P D. Rekha, C. Mason, and K. Venkateswaran. Scientific Reports 2025 (accepted). doi/10.1038/s41598-025-13974-5.C: N/A; IF: 3.9.

In Memoriam: Professor Andrez (Andrew) Pohorille (May 14, 1949, to January 6, 2024): A Legacy in Astrobiology and Computational Science. F Karouia, M Wilson, K Schweighofer, T Hoehler, and J Sokolowska. Astrobiology Vol 25, 7, 2025. C: N/A; IF: 2.6.

A Novel In Situ Green Method for Synthesizing a Palladium Nos-based Catalyst Aimed at the Selective Hydrogenation of Aldehydes in Cinnamaldehyde. A. Mehri, H. Touati, K. Kaaroud, F. Karouia, M.H.V. Baouab. Colloids and Surfaces A: Physicochemical and Engineering Aspects. Vol 719,137035, 2025.

The International Space Station has a unique and extreme microbial and chemical environment driven by use patterns. Rodolfo A Salido, Haoqi Nina Zhao, Daniel McDonald, Helena Mannochio-Russo, Simone Zuffa, Renee E Oles, Allegra T Aron, Yasin El Abiead, Sawyer Farmer, Antonio González, Cameron Martino, Ipsita Mohanty, Ceth W Parker, Lucas Patel, Paulo Wender Portal Gomes, Robin Schmid, Tara Schwartz, Jennifer Zhu, Michael R Barratt, Kathleen H Rubins, Hiutung Chu, Fathi Karouia, Kasthuri Venkateswaran, Pieter C Dorrestein, Rob Knight. Cell. 2025 Feb 27^th. C:N/A; IF: 45.5

Spaceflight Alters Host-Gut Microbiota Interactions. E. Gonzalez, MD Lee, BT Tierney, N Lipieta, P Flores, Maya Mishra, Laura Beckett, Fathi Karouia, Richard Barker, Rick Jansen, Stefan Green, Silvio Weging, Jared T Broddrick, Nitin K Singh, Daniela Bezdan, Jonathan Matthew Galazka, Nicholas JB Brereton. NPJ Biofilms Microbiomes. 2024 Aug 29;10(1):71. C:N/A; IF: N/A

The Second Space Age: Omics, Platforms, and Medicine Across Orbits. Christopher E. Mason, James Green, Konstantinos I. Adamopoulos, Evan E. Afshin, Jordan J. Baechie, Mathias Basner, Susan M Bailey, Luca Bielski, Josef Borg, Joseph Borg, Jared T Broddrick, Marissa Burke, Andrés Caicedo, Verónica Castañeda, Subhamoy Chatterjee, Christopher R Chin, George Church, Sylvain V Costes, Iwijn De Vlaminck, Rajeev I Desai, Raja Dhir, Juan Esteban Diaz, Sofia M Etlin, Zachary Feinstein, David Furman, J Sebastian Garcia-Medina, Francine Garrett-Bakelman, Stefania Giacomello, Anjali Gupta, Amira Hassanin, Nadia Houerbi, Iris Irby, Emilia Javorsky, Peter Jirak, Christopher W Jones, Khaled Y Kamal, Brian D Kangas, Fathi Karouia, JangKeun Kim, Joo Hyun Kim, Ashley S Kleinman, Try Lam, John M Lawler, Jessica A Lee, Charles L Limoli, Alexander Lucaci, Matthew MacKay, J Tyson McDonald, Ari M Melnick, Cem Meydan, Jakub Mieczkowski, Masafumi Muratani, Deena Najjar, Mariam A Othman, Eliah G Overbey, Vera Paar, Jiwoon Park, Amber M Paul, Adrian Perdyan, Jacqueline Proszynski, Robert J Reynolds, April E Ronca, Kate Rubins, Krista A Ryon, Lauren M Sanders, Patricia Savi Glowe, Yash Shevde, Michael A Schmidt, Ryan T Scott, Bader Shirah, Karolina Sienkiewicz, Maria A Sierra, Keith Siew, Corey A Theriot, Braden T Tierney, Kasthuri Venkateswaran, Jeremy Wain Hirschberg, Stephen B Walsh, Claire Walter, Daniel A Winer, Min Yu, Luis Zea, Jaime Mateus, Afshin Beheshti. Nature. 2024 Aug: 632 (8027): 995-1008. C:27; IF: 64.8

Cosmic Kidney Disease: The Effects of Spaceflight and Galactic Cosmic Radiation on Renal Structure and Function. Keith Siew, Kevin A Nestler, Charlotte Nelson, Viola D’Ambrosio, Chutong Zhong, Zhongwang Li, Alessandra Grillo, Elizabeth R Wan, Vaksha Patel, Eliah Overbey, JangKeun Kim, Sanghee Yun, Michael B Vaughan, Chris Cheshire, Laura Cubitt, Jessica Broni-Tabi, Maneera Yousef Al-Jaber, Valery Boyko, Cem Meydan, Peter Barker, Shehbeel Arif, Fatemeh Afsari, Noah Allen, Mohammed Al-Maadheed, Selin Altinok, Nourdine Bah, Samuel Border, Amanda L Brown, Keith Burling, Margareth Cheng-Campbell, Lorianna M Colón, Lovorka Degoricija, Nichola Figg, Rebecca Finch, Jonathan Foox, Pouya Faridi, Alison French, Samrawit Gebre, Peter Gordon, Nadia Houerbi, Hossein Valipour Kahrood, Frederico C Kiffer, Aleksandra S Klosinska, Angela Kubik, Han-Chung Lee, Yinghui Li, Nicholas Lucarelli, Anthony L Marullo, Irina Matei, Colleen M McCann, Sayat Mimar, Ahmed Naglah, Jérôme Nicod, Kevin M O’Shaughnessy, Lorraine Christine De Oliveira, Leah Oswalt, Laura Ioana Patras, San-huei Lai Polo, María Rodríguez-Lopez, Candice Roufosse, Omid Sadeghi-Alavijeh, Rebekah Sanchez-Hodge, Anindya S Paul, Ralf Bernd Schittenhelm, Annalise Schweickart, Ryan T Scott, Terry Chin Choy Lim Kam Sian, Willian A da Silveira, Hubert Slawinski, Daniel Snell, Julio Sosa, Amanda M Saravia-Butler, Marshall Tabetah, Erwin Tanuwidjaya, Simon Walker-Samuel, Xiaoping Yang, Yasmin, Haijian Zhang, Jasminka Godovac-Zimmermann, Pinaki Sarder, Lauren M Sanders, Sylvain V Costes, Robert AA Campbell, Fathi Karouia, Vidya Mohamed-Alis, Samuel Rodriques, Steven Lynham, Joel Ricky Steele, Sergio Baranzini, Hossein Fazelinia, Zhongquan Dai, Akira Uruno, Dai Shiba, Masayuki Yamamoto, Eduardo AC Almeida, Elizabeth Blaber, Jonathan C Schisler, Amelia J Eisch, Masafumi Muratani, Sara R Zwart, Scott M Smith, Jonathan M Galazka, Christopher E Mason, Afshin Beheshti, Stephen B WalshS. Walsh, K Siew, et al., Nature Communications. 2024 Jun 11:15(1):4923. C:26; IF: 17.69

Ethical Considerations for the Age of non-Governmental Space Exploration. Allen Seylani, Aman Singh Galsinh, Alexia Tasoula, Anu R I, Andrea Camera, Jean Calleja-Agius, Joseph Borg, Chirag Goel, JangKeun Kim, Kevin B. Clark, Saswati Das, Shehbeel Arif, Michael Boerrigter, Caroline Coffey, Nathaniel Szewczyk, Christopher E. Mason, Fathi Karouia, Hansjörg Schwertz, Afshin Beheshti, Dana Tulodziecki. Nature Communications. 2024 Jun 11;15(1)4774. C:7; IF: 17.69

Aging and Putative Frailty Biomarkers Are Altered by Spaceflight. Andrea Camera, Marshall Tabetah, Veronica Castaneda, JangKeun Kim, Aman Singh Galsinh, Alissen Haro-Vinueza, Ivonne Salinas, Allen Seylani, Shehbeel Arif, Saswati Das, Marcelo Mori, Antonio Carano, Lorraine Christine De Oloveira, Masafumi Muratani, Richard Baker, Victoria Zaksas, Chirag Goel, Eleni Dimokidis, Deanne M. Taylor, Jisu Jeong, Eliah Overbey, Cem Meydan, D. Marshall Porterfield, Juan Esteban Díaz, Andrés Caicedo, Jonathan C. Schisler, Evagelia C. Laiakis, Christopher E. Mason, Man S Kim, Fathi Karouia, Nathaniel J Szewczyk, Afshin Beheshti. Scientific Reports 2024 Jun 11;14(1):13098. C:N/A; IF: 4.97

Spaceflight induces changes in gene expression profiles linked to insulin and estrogen Insulin and Estrogen. Begum Aydogan Mathyk, Marshall Tabetah, Rashid Karim, Victoria Zaksas, JangKeun Kim, Anu R I, Masafumi Muratani, Alexia Tasoula, Ruth Subhash Singh, Yen-Kai Chen, Eliah Overbey, Jiwoon Park, Davide Povero, Joseph Borg, Remi V Klotz, Min Yu, Steven L Young, Christopher E. Mason, Nathaniel Szewczyk, Riley M. St Clair, Fathi Karouia, Afshin Beheshti. Communications Biology 2024 Jun 11;7(1):692. C:N/A; IF: 6.54

Understanding How Space Travel Affects the Female Reproductive System. Begum Aydogan Mathyk, Alexander M Quaas, Cihan Halicigil, Fathi Karouia, Michael Strug, Brent Monseur, Murat Basar, Steven L Young, Savas Tasoglu, Afshin Beheshti. NPJ Women’s Health 2024 2(1), 20. C:N/A; IF: N/A.

Planetary Protection Knowledge Gap Closure Enabling Crewed Missions to Mars. James A. Spry, Bette Siegel, Corien U. Bakermans, David W. Beaty, Mary-Sue Bell, James N. Benardini, Rosalba Bonaccorsi, Sarah L. Castro-Wallace, David Coil, Athena Coustenis, Peter Doran, Lori Fenton, David P. Fidler, Matthew Fields, Brian Glass, Stephen J. Hoffman, Fathi Karouia, Michael J. Kempf, Joel S. Levine, Robert Lindberg, Mark L. Lupisella, Javier Martin-Torres, Rakesh Mogul, Karen Olsson-Francis, Manish Patel, David Pearce, Margaret Race, Aaron B. Regberg, Petra Rettberg, Robert R. Zimmerman, Kathleen Rubins, Ondre Santolik, Kevin Y. Sato, Andrew Schuerger, Elliot Sefton-Nash, Matthew Sharkey, Nitin K. Singh, Silvio Sinibaldi, Perry Stabekis, Carol R. Stoker, Kasthuri J. Venkateswaran, Maria-Paz Zorzano-Mier. Astrobiology. 2024 Mar;24(3):230-274

Assessing microbial diversity in Yellowstone National Park hot springs using deployable automated nucleic acid extraction system. JM. Wood, Camilla Urbaniak, Ceth Parker, Nitin Singh, Season Wong, Arun Kumar, Dana Skorupa, Ashlyn Hemmah, Phoebe Laaguiby, Fathi Karouia, Brent Peyton, Scott Tighe, Kasthuri Venkateswaran. Front. Ecol. Evol., 12:1306008, 2024. C:N/A; IF:3.0

Genomic characterization and radiation tolerance of Naganishia kalamii sp. nov. and Cystobasidium onofrii sp. nov. from Mars 2020 mission assembly facilities. P. Leo,  M.de Melo Texeira, A. M. Cahnder, N. K. Singh, A, C. Simpson, A. Yurkov, F. Karouia, J. E. Stajch, C. E. Mason, K. Venkateswaran. IMA Fungus 2023. C:N/A; IF: 5.4

Comparative genomic analysis of Cohnella hashimotonis sp. nov. isolated from the International Space Station. A. C. Simpson, v. V. Ramprasad Eedara, N. K. Singh, Namita Danle,  F. Karouia, C. E. Mason, K. Venkateswaran. Front Microbiol. 2023 Jun 15;14:1166013. C:N/A; IF: 5.2

Beneficial effect of in-situ citrate-grafting of hydroxyapatite surface for water treatment. D Bouazzi, A Mehri, K Kaaroud, H Touati, F Karouia, JM Clacens, A Laghzizil, B Badraoui. Colloids and Surfaces A: Physicochemical and Engineering Aspects; Vol 666, 5 June 2023, 131366. C:1; IF: 5.2

Lab Medicine in Space, J R. Wiencek, S. Das, A. Beheshti, B E. Crucian, F. Karouia et al., Clinical Chemistry, Vol 69, issue 5, 2023, p442-449. C:N/A; IF: 9.3

Extraterrestrial Gynecology: Could Spaceflight Increase the Risk of Developing Cancer in Female Astronauts? An Updated Review. R. Drago-Ferrante, R. Di Fiore, F Karouia, Y. Subbannayya, S. Das, B. M. Mathyk, S Arif, A. P. Guevara-Cerdan, A Seylani, A. S. Galsinh, V. Kukulska, J. Borg, S. Suleiman, D. M. Porterfield, A. Camera, L.K. Christenson, A. E. Ronca, J.G. Steller, A. Beheshti, and J. Calleja-Agius. Int J Mol Sci. 2022 Jul 5:23 (13): 7465 C:25; IF: 5.6

Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station. Camilla Urbaniak; Michael D. Morrison; James B. Thissen; Fathi Karouia; David J. Smith; Satish Mehta; Crystal Jaing; Kasthuri Venkateswaran. Microbiome. 2022 Jun 29; 10(1): 100. C:15;  IF: 15.5

Low-Temperature O₃ Decomposition over Pd-TiO₂ Hybrid Catalysts. Touati H, Mehri A, Karouia F, Richard F, Batiot-Dupeyrat, Daniele S, Clacens JM. Catalysts 2022, 12 (4), 488. C:3; IF: 3.9

Investigation of Spaceflight Induced Changes to Astronaut Microbiomes. M. D. Morrison; J. B. Thissen; C. Urbaniak; F. Karouia; S. Mehta; K. Venkateswaran; D. J. Smith; and C. Jaing. Front. Microbiol., 2 Jun 2021, 12:1368. C:29; IF: 5.2

Human Neural Stem Cells Proliferate More in Space, Have a Shorter Cell Cycle, and are Larger than Ground Control Cells After Space Flight: Implications for Long-term Space Travel. Sophia Shaka,Nicholas Carpo, Victoria Tran, Fathi Karouia, and Araceli Espinosa-Jeffrey. J Stem Cells Res Dev. 2021, 7:069. C:5; IF: 4

Assessing the risk of transfer of microorganisms at the International Space Station owing to cargo delivery by commercial resupply vehicles. Snehit Satish Mhatre; Jason Wood; Aleksandra Checinska Sielaff; Mora Maximilian; Stefanie Duller; Nitin kumar Singh; Fathi Karouia; Christine Moissl Eichinger; Kasthuri Venkateswaran. Front. Microbiol., 6 Nov 2020; Vol 11. C:12; IF: 5.2

Draft Genome Sequences of Lactobacillales Isolated from the International Space Station. Bharadwaj AR, Singh NK, Wood JM, Debieu M, O’Hara NB,Karouia F, Mason CE, Venkateswaran K. Microbiol Resour Announc. 2020 Sep 24; 9(39). C:2; IF: 0.58

Draft Genome Sequences of Enterobacteriales Strains Isolated from the International Space Station. Bharadwaj AR, Daudu R, Singh NK, Wood JM, Debieu M, O’Hara NB,Karouia F, Mason CE, Venkateswaran K. Microbiol Resour Announc. 2020 Sep 10; 9(37). C:2; IF: 0.58

Validating an automated nucleic acid extraction device for omics in space using whole cell microbial reference standards. Camilla Urbaniak; Season Wong; Scott Tighe; Arun Kumar; Bo Liu; Ceth Parker; Jason Wood; Nitin Singh; Dana Skorupa; Brent Peyton; Ryan Jenson; Fathi Karouia; Julie Dragon; Kasthuri Venkateswaran. July 2020; Frontiers in Microbiology 11:1909. C:10; IF: 5.2

Crewmember microbiota may influence taxonomy of ISS habitable surface metagenomes. Aram Avila-Herrera; James Thissen; Camilla Urbaniak; Nicholas A. Be; David J. Smith; Fathi Karouia; Satish Mehta; Kasthuri Venkateswaran; Crystal Jaing. PLoS One. 2020 Apr 29;15(4). C:53; IF: 3.7

Human Neural Stem Cells Flown into Space Proliferate and Generate Young Neurons. Carlos Cepeda, Laurent Vergnes, Nicholas Carpo, Matthew Schibler, Laurent Bentolila, Fathi Karouia, and Araceli Espinosa-Jeffrey. Appl. Sci. 2019, 9 (19), 4042. C:6; IF: 2.7

Gene Expression Measurement Module (GEMM) for space application: Design and validation. Peyvan K, Karouia F, Cooper JJ, Chamberlain J, Suciu D, Slota M, and Pohorille A. Life Sci Space Res. 2019 Aug;22:55-67. C:5; IF: 2.73

Characterization of the Total and Viable bacterial and fungal communities associated with the International Space Station Surfaces. Aleksandra Checinska Sielaff; Camilla Urbaniak; Ganesh Babu Malli Mohan; Victor G. Stepanov; Quyen Tran; Wood JM; Minich J; McDonald D; Mayer T; Knight R; Fathi Karouia; George E. Fox; Kasthuri Venkateswaran. Microbiome. 2019 Apr 8;7(1): 50. C:173; IF: 15.5

Evaluation of Acquired Antibiotic Resistance in Escherichia coli Exposed to Long-Term Low-Shear Modeled Microgravity and Background Antibiotic Exposure. Madhan Tirumalai, Fathi Karouia, Quyen Tran, Victor G. Stepanov, Rebekah Bruce, C. Mark Ott, Duane Pierson, and George Fox. MBio. 2019 Jan 15; 10(1). C:40; IF: 7.78

International Space Station conditions alter genomics, proteomics, and metabolomics in Aspergillus Nidulans. Jillian Romsdahl, Adriana Blachowicz, Abby Chiang, Yi-Ming Chiang, Junko Yaegashi, Stefanie Countryman, Fathi Karouia, Markus Kalkum, Jason E. Stajich, Kasthuri Venkateswaran, and Clay C.C. Wang. Appl Microbiol Biotechnol. 2019 Feb; 103(3):1363-1377. C:29; IF: 5.56

Succession and persistence of microbial communities and antibiotic resistance genes associated with International Space Station environmental surfaces. Nitin Singh, Jason Wood, Fathi Karouia, and Kasthuri Venkateswaran. Microbiome. 2018 Nov 13; 6(1): 204. C:123; IF: 15.5

Toward Biotechnology in Space: High-throughput Instruments for in situ biological Research beyond Earth. Karouia F, Peyvan K, and Pohorille A. Biotechnol Adv. 2017 Nov 15;35(7):905-32. C:54; IF: 16

Microbial Characteristics of the International Space Station Environmental Surfaces. Kasthuri Venkateswaran, Aleksandra Checinska, Nitin Singh, Ganesh B. M. Mohan, Camilla Urbaniak, Adriana Blachowicz, George E. Fox, Crystal Jaing, Jonathan E. Allen, Kenneth Frey, David Smith, Satish Mehta, Nicholas H. Bergman, Fathi Karouia, Clay Wang, Nancy Keller, Duane L. Pierson, and Jay Perry. ICES-2017-131. C:8; IF: 3.26

The Adaptation of E. coli Cells Grown in Simulated Microgravity for an Extended Period is Both Environmental and Genomic. Madhan Tirumalai, Fathi Karouia , Quyen Tran, C. Mark Ott, Duane Pierson, Rebekah Bruce, and George Fox. NPJ Microgravity. 2017 May 23;3:15. C:33; IF: 4.97

Cellular Responses and Gene Expression Profile Changes due to Bleomycin-Induced DNA Damage in Human Fibroblasts in Space. Honglu Wu; Tao Lu; Ye Zhang; Yared Kidane; Alan Feiveson; Louis Stodieck; Fathi Karouia; Govindarajan Ramesh; and Larry Rohde. PLoS One. 2017 Mar 1;12(3). C:32; IF: 3.7

Detection of DNA damage by space radiation in human fibroblasts flown on the International Space Station. Tao Lu, Ye Zhang, Michael Wong, Alan Feiveson, Ramona Gaza, Nicholas Stoffle, Huichen Wang, Bobby Wilson, Larry Rohde, Luis Stodieck, Fathi Karouia, and Honglu Wu. Life Sci Space Res. Volume 12, Feb 2017, P24-31. C:44; IF: 2.73

Transient gene and miRNA expression profile changes of confluent human fibroblast cells in space. Ye Zhang, Tao Lu, Michael Wong, Xiaoyu Wang, Louis Stodieck, Fathi Karouia, Michael Story, Honglu Wu. FASEB J. 2016 Jun;30(6):2211-24. C:31; IF: 5.834

Microorganisms, organic carbon and oxidant activity interactions in hyper-arid Mars-like soils: Implications in soil habitability. Julio E. Valdivia-Silva, Fathi Karouia, Rafael Navarro-González, and Christopher McKay. PALAIOS, 2016, V. 30, 1-9. C:10; IF: 1.60

GEMM: An Automated Instrument for in-situ Gene Expression Measurements on Board the International Space Station. F Karouia, K Peyvan, D Bajorins, LS Stodieck, AJ Ricco, O Santos, and A Pohorille. Results and Opportunities-The Decade of Utilization, Vol. 114, Science and Technology Series, American Astronautical Society, 2013, pp141-142, ISBN 978-0-87703-594-7. C:N/A; IF: N/A

Long-term exposure of bacterial cells to simulated microgravity, Karouia F, Tirumalai MR, Nelman-Gonzalez MA, Sams CF, Ott MC, Pierson DL, Willson RC, Fofanov Y, and Fox GE. Proc. SPIE Vol 8521, Instruments, Methods, and Missions for Astrobiology XV, 85210K 1-6, 2012. C:3; IF: 1.13

Long-term Effects of Simulated Microgravity on Microbial Gene Expression. Tirumalai MR, Karouia F, Stepanov V, Tran Q, Pierson D and Fox GE. ISSO V09, pp178-180, 2011. C:3; IF: N/A

Martian Soil Biosensors Based on Dielectric Spectroscopy. John H. Miller, Jie Fang, David Warnflash, David S. McKay, Jeffrey A. Jones, and Fathi Karouia. ISSO V07, pp61-66, 2008. C:2; IF: N/A

Simulated Microgravity on Microbial Gene Expression. Fox GE, Willson RC, Pierson DL, Tirumalai MT, and Karouia F. ISSO V07, pp58-60, 2008. C:2; IF: N/A

Paradoxical DNA Repair and Peroxide Resistance Gene Conservation in Bacillus pumilus SAFR-032.Jason Gioia Madhan R Tirumalai, Shailaja Yerrapragada, Madhan R Tirumalai, Indrani Dasgupta, Lina Bokhetache, Yamei Liu, Prahathees E. Moorthy, Brian Davis McWilliams, Adeola A Olowu, Johnathan Siefert, Fathi Karouia, Kenneth D. Clinkenbeard, Avani Verma, Prince Buzumbo, Hiba Zwiya, Okezie Igboeli, Akif Uzman, Xiang Qin, Huaiyang Jiang, Sarah Highlander, Kasthuri Venkateswaran, George E Fox, George Weinstock. PLoS ONE. 2007 Sep 26;2(9):e928. C:155; IF: 3.7

Biosensors Based on Dielectric Spectroscopy, John H. Miller, Jaroslaw Wosik, David S. McKay, Jeffrey A. Jones, Fathi Karouia, David Warnflash, Dharmakeerthi Nawarathna, ISSO V05, pp33-38, 2006. C:2; IF: N/A.

A multi-goal Mars analogue expedition (expedition two) to the Arkaroola region, Australia. Jonathan DA Clarke, Rocky Persaud, Shannon Rupert, M Bishop, A Brown, A Clarke, JP Clarke, R Clarke, N Cutler, S Dawson, K Fitzsimmons, V Gostin, J Heldmann, S Jordan, F Karouia, P Krins, E Martinez, V Matic, G Murphy, A Rupert, N Stansfield, M Tanner, M Thomas, V Waclawik, J Waldie, D Willson. Mars Analog Research, Vol. 111, Science and Technology Series, American Astronautical Society, 2006, pp3-15, ISBN -87703-529-6. C:5; IF: N/A

PR or Perish? Promotion and Outreach Opportunities in Mars Analogue Research, Jennifer H. Laing, Reyna Jenkyns, and Fathi Karouia, Mars Analog Research, Vol. 111, Science and Technology Series, American Astronautical Society, 2006, pp39-52, ISBN -87703-529-6. C:2; IF:N/A

Effect of an artificial RNA marker on gene expression in Escherichia coli, Tucker DL, Karouia F, Wang J, Luo Y, Li TB, Willson RC, Fofanov Y, Fox GE: Applied Environmental Microbiology, 2005 july, 71(7):4156-9. C:7; IF:4.79

Characterization of Evolving Bacterial Populations, G. E. Fox, M. Travisano, R. Goldman, and F. Karouia, ISSO V02, pp85-86, 2003. C:2; IF:N/A

Review Articles

Understanding How Space Travel Affects the Female Reproductive System. Begum Aydogan Mathyk, Alexander M Quaas, Cihan Halicigil, Fathi Karouia, Michael Strug, Brent Monseur, Murat Basar, Steven L Young, Savas Tasoglu, Afshin Beheshti. NPJ Women’s Health 2024 2(1), 20. C:N/A; IF: N/A.

Lab Medicine in Space, J R. Wiencek, S. Das, A. Beheshti, B E. Crucian, F. Karouia et al., Clinical Chemistry, Vol 69, issue 5, 2023, p442-449. C:N/A; IF: 9.3

Extraterrestrial Gynecology: Could Spaceflight Increase the Risk of Developing Cancer in Female Astronauts? An Updated Review. R. Drago-Ferrante, R. Di Fiore, F Karouia, Y. Subbannayya, S. Das, B. M. Mathyk, S Arif, A. P. Guevara-Cerdan, A Seylani, A. S. Galsinh, V. Kukulska, J. Borg, S. Suleiman, D. M. Porterfield, A. Camera, L.K. Christenson, A. E. Ronca, J.G. Steller, A. Beheshti, and J. Calleja-Agius. Int J Mol Sci. 2022 Jul 5:23 (13): 7465 C:25; IF: 5.6

Toward Biotechnology in Space: High-throughput Instruments for in situ biological Research beyond Earth. Karouia F, Peyvan K, and Pohorille A. Biotechnol Adv. 2017 Nov 15;35(7):905-32. C:47; IF:14.23.

Books & Chapters  

Principles of Clinical Medicine for Space Flight, JA Jones, F Karouia, L Pinsky, O Cristea. Chapter 2: Radiation and Radiation Disorder, Edited by M. Barratt, 2nd Edition. Springer, ISBN-978-1-4939-9889-0, Dec 2019. C:5; IF:N/A.

Radiobiology of Space Radiation, Jones, J. A., Montesinos C, Karouia, F, Popov D, Boreham D, Cristea C, and Greenberger J. Chap VII: Sporadic High LET Radiation. CMCR-Radiobiology and Methods Public Textbook. Joel. S Greenberger Editor, Pittsburg, PA. June 26^th, 2018. C:N/A; IF:N/A.

Comprehensive Toxicology, Jones, J. A., Karouia, F. O. Cristea, RC Casey, D. Popov, and V Maliev. Ionizing Radiation as a Carcinogen. (2018). 3rd Edition. Volume 7, pp. 183-225. Oxford: Elsevier Ltd. ISBN:9780081006016. C:10; IF:N/A.

Comprehensive Toxicology, Jones, J. A., Casey, R. C., and Karouia, F. Chapter 11: Ionizing Radiation as a Carcinogen, 2nd Edition, Elsevier, ISBN-13: 978-0-08-046868-6, 2010. C:12; IF:N/A.

Principles of Clinical Medicine for Space Flight, Jones, J. A., and Karouia, F. Chapter 25: Radiation Disorder, Edited by M. Barratt, ISBN: 9780387988429, 2008. C:13; IF:N/A.

NASA Missions

Human Research

InSPA-StemCellEX-H (NG-21 to present)

StemCellEX-H Pathfinder (NG-19)

ISS Microbial Observatory of Pathogens (MT-2) (SpX-11 to 16)

Food Physiology (Co-managed by ISSMP) (SpX-18 to present)

ISS Microbiome of the Built Environment

Microbial Tracking (MT-1) (SpX-5, -6, and -8)

Three-dimensional Microbial Mapping (3DMM) of the ISS Environment (SpX-21)

Cell Biology

Micro-7 (SpX-3)

Micro-11 (SpX-14)

Bioscience-04 (SpX-16, -21)

Micro-15 (SpX-18)

Microbiology Research

Micro-8 (SpX-4)

Micro-9 (SpX-8)

Micro-10 (SpX-8)

Life Support Systems

Micro-12 (SpX-15)

Astrobiology – Evolutionary Microbiology

MVP-Cell-02 (SpX-18 and 28)

Awards & Others

Awards

NASA ARC Group Achievement Award (2017, 2025);

NASA ARC Recognition Award (2019);

FILMSS Star Award (2016),

NASA ARC Space Flight Award (2016);

National Science Foundation/American Astronomical Society Award (2013; 2012; 2011);

International Council of Science/COSPAR Astrobiology Award (2012);

International Council of Science/COSPAR Planetary Protection Award (2012);

NASA Astrobiology Institute Conference Award (2011);

National Research Council Postdoctoral fellowship (Denied-2009);

NASA Postdoctoral Fellowship (2009);

NASA Astrobiology Institute Scholarship (2008);

Institute for Space Systems Operations Postdoctoral Fellowship (2008);

European Space Agency Astronaut Candidate (2008).

Others

Ascent Deep Tech Accelerator, University of Colorado Boulder (2024)

NASA TOPS Open Science: Ethos of Open Science (2023)

National Science Foundation/I-Corps, Research to Market, University of Colorado Boulder (2023)

Space Tech Accelerator, TechStart/Saudi Space Agency (2022)

Life sciences/Health Care, Entrepreneurship Program, University of California San Francisco (2020)

Certification in Project Management (Kepner-Tregoe) (2015)

Certification for use of Radioisotopes for Scientific Research (2013)

Certification as Ambassador for the International Space Station (2013)