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CAPE CANAVERAL, Fla. -- An exhaust cloud billows around Launch Pad 39A at NASA's Kennedy Space Center in Florida as space shuttle Discovery lifts off at 4:53 p.m. EST to begin the STS-133 mission and its final flight to the International Space Station. Discovery and its six-member crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the orbiting outpost. Discovery is flying on its 39th mission and is scheduled to be retired following STS-133. This is the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit Photo credit: NASA/Sandra Joseph and Kevin O'Connell