\{"nodes": \{"Altered Gravity": \{"position": {[}-432.115, -324.397{]}, "category": "Hazard", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Distance from Earth": \{"position": {[}-645.613, 203.289{]}, "category": "Hazard", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Hostile Closed Environment": \{"position": {[}-626.603, -61.734{]}, "category": "Hazard", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Isolation and Confinement": \{"position": {[}-623.678, 93.191{]}, "category": "Hazard", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Radiation": \{"position": {[}-650.0, -303.951{]}, "category": "Hazard", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Astronaut Selection": \{"position": {[}-123.566, -342.485{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Atmospheric Conditions": \{"position": {[}-385.321, 13.762{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Circadian Misalignment": \{"position": {[}-339.989, 83.754{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Clinically Significant Immune Dysregulation": \{"position": {[}82.621, -5.112{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Crew Capability": \{"position": {[}351.687, -208.008{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Crew Health and Performance System": \{"position": {[}-126.49, 337.766{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Detect Immune Changes": \{"position": {[}32.901999999999994, 89.99564680390031{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Detect Long Term Health Outcomes": \{"position": {[}571.035, 315.747{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Individual Factors": \{"position": {[}-120.641, -211.153{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Individual Readiness": \{"position": {[}312.205, -138.016{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Lab Blood Monitoring": \{"position": {[}103.093, 210.367{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Medical Illness": \{"position": {[}211.305, -49.151{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Medical Prevention Capability": \{"position": {[}290.27, 89.258{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Medical Treatment Capability": \{"position": {[}369.235, 211.153{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Microbial Virulence Factors": \{"position": {[}-8.043, -296.873{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Oxidative Stress": \{"position": {[}-391.17, -230.814{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Persistent Subclinical Immune Dysregulation": \{"position": {[}-120.641, -102.628{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Stress Relieving VR": \{"position": {[}-322.441, 244.183{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Vehicle Design": \{"position": {[}-506.693, 265.416{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Exercise": \{"position": {[}-120.641, 47.578{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Inflammation": \{"position": {[}66.535, -133.298{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Microbiome": \{"position": {[}-337.064, -79.035{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Nutrients": \{"position": {[}-484.758, -134.871{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Probiotics": \{"position": {[}-211.305, 50.724{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Stress": \{"position": {[}-319.516, 163.182{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Supplements": \{"position": {[}-211.305, 181.269{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Surveillance": \{"position": {[}338.526, 330.689{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Behavioral (Risk)": \{"position": {[}192.295, -258.338{]}, "category": "Associated Risk", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Dust (Risk)": \{"position": {[}-619.291, 15.335{]}, "category": "Associated Risk", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Food and Nutrition (Risk)": \{"position": {[}-581.271, -242.61{]}, "category": "Associated Risk", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "HSIA (Risk)": \{"position": {[}-635.377, 342.485{]}, "category": "Associated Risk", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Hypoxia, CO2 (Risks)": \{"position": {[}-604.668, -160.822{]}, "category": "Associated Risk", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Microhost (Risk)": \{"position": {[}-215.692, -277.999{]}, "category": "Associated Risk", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Pharm (Risk)": \{"position": {[}129.415, 336.194{]}, "category": "Associated Risk", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Sleep (Risk)": \{"position": {[}-511.08, 167.9{]}, "category": "Associated Risk", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Team (Risk)": \{"position": {[}285.883, -322.038{]}, "category": "Associated Risk", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Flight Recertification": \{"position": {[}619.291, 23.199{]}, "category": "Outcome", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Long Term Health Outcomes": \{"position": {[}610.517, 108.132{]}, "category": "Outcome", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Loss of Crew Life": \{"position": {[}629.528, -79.821{]}, "category": "Outcome", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Loss of Mission Objectives": \{"position": {[}471.597, -329.116{]}, "category": "Outcome", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Loss of Mission": \{"position": {[}650.0, -328.329{]}, "category": "Outcome", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Task Performance": \{"position": {[}410.18, -270.135{]}, "category": "Outcome", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "Evacuation": \{"position": {[}486.22, -138.016{]}, "category": "Outcome", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}, "HSP": \{"position": {[}-533.1238244853738, -325.3921668472374{]}, "category": "Contributing Factor", "subgraph": \{"nodes": \{\}, "edges": \{\}\}\}\}, "edges": \{"0": \{"source": "Dust (Risk)", "dest": "Atmospheric Conditions", "loe": 2\}, "1": \{"source": "Hostile Closed Environment", "dest": "Atmospheric Conditions", "loe": 2\}, "2": \{"source": "Hypoxia, CO2 (Risks)", "dest": "Atmospheric Conditions", "loe": 2\}, "3": \{"source": "Distance from Earth", "dest": "Circadian Misalignment", "loe": 2\}, "4": \{"source": "Hostile Closed Environment", "dest": "Circadian Misalignment", "loe": 2\}, "5": \{"source": "Sleep (Risk)", "dest": "Circadian Misalignment", "loe": 2\}, "6": \{"source": "Individual Factors", "dest": "Clinically Significant Immune Dysregulation", "loe": 2\}, "7": \{"source": "Persistent Subclinical Immune Dysregulation", "dest": "Clinically Significant Immune Dysregulation", "loe": 2\}, "8": \{"source": "Individual Readiness", "dest": "Crew Capability", "loe": 2\}, "9": \{"source": "Team (Risk)", "dest": "Crew Capability", "loe": 2\}, "10": \{"source": "HSIA (Risk)", "dest": "Crew Health and Performance System", "loe": 2\}, "11": \{"source": "Vehicle Design", "dest": "Crew Health and Performance System", "loe": 2\}, "12": \{"source": "Clinically Significant Immune Dysregulation", "dest": "Detect Immune Changes", "loe": 2\}, "13": \{"source": "Lab Blood Monitoring", "dest": "Detect Immune Changes", "loe": 2\}, "14": \{"source": "Persistent Subclinical Immune Dysregulation", "dest": "Detect Immune Changes", "loe": 2\}, "15": \{"source": "Long Term Health Outcomes", "dest": "Detect Long Term Health Outcomes", "loe": 2\}, "16": \{"source": "Surveillance", "dest": "Detect Long Term Health Outcomes", "loe": 2\}, "17": \{"source": "Astronaut Selection", "dest": "Individual Factors", "loe": 2\}, "18": \{"source": "Behavioral (Risk)", "dest": "Individual Readiness", "loe": 2\}, "19": \{"source": "Medical Illness", "dest": "Individual Readiness", "loe": 2\}, "20": \{"source": "Medical Treatment Capability", "dest": "Individual Readiness", "loe": 2\}, "21": \{"source": "Crew Health and Performance System", "dest": "Lab Blood Monitoring", "loe": 2\}, "22": \{"source": "Clinically Significant Immune Dysregulation", "dest": "Medical Illness", "loe": 2\}, "23": \{"source": "Medical Prevention Capability", "dest": "Medical Illness", "loe": 2\}, "24": \{"source": "Microbial Virulence Factors", "dest": "Medical Illness", "loe": 2\}, "25": \{"source": "Inflammation", "dest": "Medical Illness", "loe": 2\}, "26": \{"source": "Crew Health and Performance System", "dest": "Medical Prevention Capability", "loe": 2\}, "27": \{"source": "Pharm (Risk)", "dest": "Medical Prevention Capability", "loe": 2\}, "28": \{"source": "Crew Health and Performance System", "dest": "Medical Treatment Capability", "loe": 2\}, "29": \{"source": "Detect Immune Changes", "dest": "Medical Treatment Capability", "loe": 2\}, "30": \{"source": "Pharm (Risk)", "dest": "Medical Treatment Capability", "loe": 2\}, "31": \{"source": "Altered Gravity", "dest": "Microbial Virulence Factors", "loe": 2\}, "32": \{"source": "Hostile Closed Environment", "dest": "Microbial Virulence Factors", "loe": 2\}, "33": \{"source": "Microhost (Risk)", "dest": "Microbial Virulence Factors", "loe": 2\}, "34": \{"source": "Hypoxia, CO2 (Risks)", "dest": "Oxidative Stress", "loe": 2\}, "35": \{"source": "Microbiome", "dest": "Oxidative Stress", "loe": 2\}, "36": \{"source": "Nutrients", "dest": "Oxidative Stress", "loe": 2\}, "37": \{"source": "Radiation", "dest": "Oxidative Stress", "loe": 2\}, "38": \{"source": "HSP", "dest": "Oxidative Stress", "loe": 2\}, "39": \{"source": "Altered Gravity", "dest": "Persistent Subclinical Immune Dysregulation", "loe": 2\}, "40": \{"source": "Atmospheric Conditions", "dest": "Persistent Subclinical Immune Dysregulation", "loe": 2\}, "41": \{"source": "Circadian Misalignment", "dest": "Persistent Subclinical Immune Dysregulation", "loe": 2\}, "42": \{"source": "Individual Factors", "dest": "Persistent Subclinical Immune Dysregulation", "loe": 2\}, "43": \{"source": "Oxidative Stress", "dest": "Persistent Subclinical Immune Dysregulation", "loe": 2\}, "44": \{"source": "Exercise", "dest": "Persistent Subclinical Immune Dysregulation", "loe": 2\}, "45": \{"source": "Microbiome", "dest": "Persistent Subclinical Immune Dysregulation", "loe": 2\}, "46": \{"source": "Nutrients", "dest": "Persistent Subclinical Immune Dysregulation", "loe": 2\}, "47": \{"source": "Stress", "dest": "Persistent Subclinical Immune Dysregulation", "loe": 2\}, "48": \{"source": "Crew Health and Performance System", "dest": "Stress Relieving VR", "loe": 2\}, "49": \{"source": "Distance from Earth", "dest": "Vehicle Design", "loe": 2\}, "50": \{"source": "HSIA (Risk)", "dest": "Vehicle Design", "loe": 2\}, "51": \{"source": "Crew Health and Performance System", "dest": "Exercise", "loe": 2\}, "52": \{"source": "Clinically Significant Immune Dysregulation", "dest": "Inflammation", "loe": 2\}, "53": \{"source": "Oxidative Stress", "dest": "Inflammation", "loe": 2\}, "54": \{"source": "Persistent Subclinical Immune Dysregulation", "dest": "Inflammation", "loe": 2\}, "55": \{"source": "Hostile Closed Environment", "dest": "Microbiome", "loe": 2\}, "56": \{"source": "Isolation and Confinement", "dest": "Microbiome", "loe": 2\}, "57": \{"source": "Microhost (Risk)", "dest": "Microbiome", "loe": 2\}, "58": \{"source": "Distance from Earth", "dest": "Nutrients", "loe": 2\}, "59": \{"source": "Food and Nutrition (Risk)", "dest": "Nutrients", "loe": 2\}, "60": \{"source": "Hostile Closed Environment", "dest": "Nutrients", "loe": 2\}, "61": \{"source": "Probiotics", "dest": "Nutrients", "loe": 2\}, "62": \{"source": "Supplements", "dest": "Nutrients", "loe": 2\}, "63": \{"source": "Crew Health and Performance System", "dest": "Probiotics", "loe": 2\}, "64": \{"source": "Pharm (Risk)", "dest": "Probiotics", "loe": 2\}, "65": \{"source": "Hostile Closed Environment", "dest": "Stress", "loe": 2\}, "66": \{"source": "Isolation and Confinement", "dest": "Stress", "loe": 2\}, "67": \{"source": "Sleep (Risk)", "dest": "Stress", "loe": 2\}, "68": \{"source": "Stress Relieving VR", "dest": "Stress", "loe": 2\}, "69": \{"source": "Crew Health and Performance System", "dest": "Supplements", "loe": 2\}, "70": \{"source": "Pharm (Risk)", "dest": "Supplements", "loe": 2\}, "71": \{"source": "Medical Illness", "dest": "Behavioral (Risk)", "loe": 2\}, "72": \{"source": "Behavioral (Risk)", "dest": "Team (Risk)", "loe": 2\}, "73": \{"source": "Medical Illness", "dest": "Flight Recertification", "loe": 2\}, "74": \{"source": "Medical Illness", "dest": "Long Term Health Outcomes", "loe": 2\}, "75": \{"source": "Medical Illness", "dest": "Loss of Crew Life", "loe": 2\}, "76": \{"source": "Medical Treatment Capability", "dest": "Loss of Crew Life", "loe": 2\}, "77": \{"source": "Evacuation", "dest": "Loss of Crew Life", "loe": 2\}, "78": \{"source": "Task Performance", "dest": "Loss of Mission Objectives", "loe": 2\}, "79": \{"source": "Evacuation", "dest": "Loss of Mission Objectives", "loe": 2\}, "80": \{"source": "Loss of Mission Objectives", "dest": "Loss of Mission", "loe": 2\}, "81": \{"source": "Crew Capability", "dest": "Task Performance", "loe": 2\}, "82": \{"source": "Medical Illness", "dest": "Evacuation", "loe": 2\}, "83": \{"source": "Medical Treatment Capability", "dest": "Evacuation", "loe": 2\}\}, "date": "11-09-2023"\}