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Determination of Intracellular and Extracellular Fluid Volume in Humans in Space Flight (Sprut-MBI)


Overview | Description | Applications | Operations | Results | Publications | Imagery

Experiment Overview

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Brief Summary

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Principal Investigator(s)

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Sponsoring Space Agency

Russian Federal Space Agency (Roscosmos)

Sponsoring Organization

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ISS Expedition Duration:

November 2000 - April 2006

Expeditions Assigned


Previous ISS Missions

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Experiment Description

Research Overview

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Investigation of a state of human liquid media, assessment of adaptation mechanisms and prevention of unfavorable impact of zero-gravity on the hydration status and post-flight orthostatic tolerance.

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Space Applications

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Earth Applications

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Operational Requirements

Sprut-K Kit to determine different human liquid volumes by measuring the impedance of the body and its segments, Body mass meter with a range from 50 kg to 100 kg with an accuracy of 0.25 kg, Hematokrit microcentrifuge to separate plasma from erythrocytes, laptop and power supply unit.

Operational Protocols

Determination of volumes of intracellular and intercellular liquid, body's total liquid, circulating blood and relation between cellular and liquid blood component.

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Results/More Information

The dynamics of a hydration status of a cosmonaut will be recorded, including analysis of homosapien's separate liquid regions in space flight conditions.

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Results Publications

    Shargin YG, Noskov VB., Nichiporuk IA, Kotov AN, Morukov BV.  Bioimpedance Analysis of Fluids and Body Composition Under the Conditions of Short-term Space Flight or Hypokinesia. Human Physiology. 2006; 32(5): 622-625. DOI: 10.1134/S0362119706050197.
    Noskov VB., Nikolaev DV, Tuikin SA, Kozharinov VI, Grachev VA.  A Portable Impedance Meter for Monitoring Liquid Compartments of the Human Body Under Space Flight Conditions. Biomedical Engineering. 2007; 41(2): 94-96. DOI: 10.1007/s10527-007-0020-7.
    Noskov VB., Nichiporuk IA, Grigoriev AI.  Dynamics of the Body Liquids and Composition in Long-duration Space Flight (Bioimpedance Analysis). Human Physiology. 2011; 37: 821-825. DOI: 10.1134/S0362119711070231.

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Ground Based Results Publications

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ISS Patents

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Related Publications

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Related Websites
  • Energia - Science Research on the ISS Russian Segment
  • Coordinating Scientific and Technical Council of the Russian Space Agency [Russian]
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    image Sprut-MBI Kit.
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    Information provided by the investigation team to the ISS Program Scientist's Office.
    If updates are needed to the summary please contact JSC-ISS-Program-Science-Group. For other general questions regarding space station research and technology, please feel free to call our help line at 281-244-6187 or e-mail at JSC-ISS-Payloads-Helpline.