Fact Sheet

Text Size

The effect of long-term microgravity exposure on cardiac autonomic function by analyzing 48-hours electrocardiogram (Biological_Rhythms_48hrs)


Overview | Description | Applications | Operations | Results | Publications | Imagery

Experiment Overview

This content was provided by Chiaki Mukai, Ph.D., M.D., and is maintained in a database by the ISS Program Science Office.

Information provided courtesy of the Japan Aerospace and Exploration Agency (JAXA).
Brief Summary

The objective of this study is to examine the accurate circadian variation of cardiac autonomic function by space flight. The crew will wear an Actiwatch for 96-hour and an electrocardiograph (ECG) for 48-hour. The crew conducts two In-flight data collections along with pre- and post-BDC.

Principal Investigator(s)

  • Chiaki Mukai, Ph.D., M.D., Japan Aerospace Exploration Agency (JAXA), Tsukuba, Japan
  • Co-Investigator(s)/Collaborator(s)

  • Hiroshi Ohshima, Ph.D., M.D., Japan Aerospace Exploration Agency (JAXA), Tsukuba, Japan
  • Developer(s)

    Japan Aerospace Exploration Agency (JAXA), Tsukuba, , Japan

    Sponsoring Space Agency

    Japan Aerospace Exploration Agency (JAXA)

    Sponsoring Organization

    Information Pending

    ISS Expedition Duration:

    May 2012 - March 2014

    Expeditions Assigned


    Previous ISS Missions

    We conducted continuous 24-hour RR intervals measurement in ten crews for preliminary data of this project. The preliminary data showed various changes on biological rhythms and some biological rhythm of crews showed prolonged for 24hours or more than those before and after flight.

    ^ back to top

    Experiment Description

    Research Overview

    • To clarify the change of an accurate biological clock from space circumstance.

    • We will evaluate continuous 48-hour RR intervals measurement on Holter ECG ,and sleep/wake rhythm on actiwatch for 96-hour.

    • This research will be analyzed for improving the health care technology of long duration astronauts, for checking out the difference of them between before and after the flight on the earth and during long-duration space flight.


    Information Pending

    ^ back to top


    Space Applications

    Information Pending

    Earth Applications

    Information Pending

    ^ back to top


    Operational Requirements

    Information Pending

    Operational Protocols

    Information Pending

    ^ back to top

    Results/More Information

    ^ back to top

    Related Websites

    ^ back to top


    image Holter ECG. Image courtesy of JAXA.
    + View Larger Image

    Information provided by the investigation team to the ISS Program Scientist's Office.
    If updates are needed to the summary please contact JSC-ISS-Program-Science-Group. For other general questions regarding space station research and technology, please feel free to call our help line at 281-244-6187 or e-mail at JSC-ISS-Payloads-Helpline.