Investigation of the Effects of Space Flight Factors on Bacteriophages (Bacteriophage) - 10.25.17

Overview | Description | Applications | Operations | Results | Publications | Imagery

ISS Science for Everyone

Science Objectives for Everyone
Study of space flight factors effect on medical, diagnostic and genetic characteristics.
Science Results for Everyone
Information Pending

The following content was provided by S. Yu. Pchelintsev, V G. Popov, G. Y. Scherbakov, M.D., and is maintained in a database by the ISS Program Science Office.
Experiment Details

OpNom:

Principal Investigator(s)
S. Yu. Pchelintsev, Biopreparat, Russia
V G. Popov, Russia
G. Y. Scherbakov, M.D., Biopreparat, Russia

Co-Investigator(s)/Collaborator(s)
Information Pending

Developer(s)
Information Pending

Sponsoring Space Agency
Russian Federal Space Agency (Roscosmos)

Sponsoring Organization
Information Pending

Research Benefits
Information Pending

ISS Expedition Duration
October 2009 - September 2010

Expeditions Assigned
21/22,23/24

Previous Missions
Information Pending

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Experiment Description

Research Overview
Information Pending

Description
Provision of the ground reproduction and the result of bacteriophages on sensitive cultures. Test of bacteriophages delivery and exposure conditions in a space flight. Investigation of biological and genetical characteristics of bacteriophages. Provision of the clone collection with heritable deviations in morphological characteristics. Production of strains with a new spectrum of lytic effect.

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Applications

Space Applications
Information Pending

Earth Applications
Information Pending

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Operations

Operational Requirements and Protocols
Bacteriofage will use the Case Bioecologia and Thermostat Cryogem-03.

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Decadal Survey Recommendations

Information Pending

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Results/More Information

Of the lyophilically dried bacteriophages exposed on the ISS one, Staphylococcus aureus bacteriophage exhibited increased lytic activity. Data indicated that in the lyophilically dried forms of bacteriophages exposed to space factors, the structure of particles was unchanged and the heads of the phage particles contain DNA. The biological properties of the bacteriophages (morphology of negative colonies, spectrum of lytic action, and stability under the influence of fluctuating pH levels) do not change relative to initial data. All studied bacteriophages retained their viability and biological activity after being in space for 3 months. However, it was noted that the concentration of bacteriophages was an order of magnitude lower than the initial concentration.

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Related Websites
Energia - Science Research on the ISS Russian Segment

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Imagery