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DNA Repair in Microgravity: Investigation of the Effects of High Levels of Radiation on DNA Repair Mechanisms in Microgravity (DNARM)


Overview | Description | Applications | Operations | Results | Publications | Imagery

Experiment Overview

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Brief Summary

DRM (DNA Repair in Microgravity) is a study of the effects of ultraviolet radiation (375 nm) on the DNA repair of the bacteria Escherichia coli in microgravity.

Principal Investigator(s)

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Sponsoring Space Agency

Russian Federal Space Agency (Roscosmos)

Sponsoring Organization

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Research Benefits

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ISS Expedition Duration

April 2006 - September 2006

Expeditions Assigned


Previous ISS Missions

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Experiment Description

Research Overview

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To study the effect of high level radiation on DNA reparation mechanisms in microgravity conditions.

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Space Applications

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Earth Applications

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Operational Requirements

The electronic cotrol module serves to supply power to the irradiation and ventilation modules, as well as to control the process parameters. A ventilation module is designed to cool the UV camera, electromagnetic interference filter and voltage regulators of the electronic control module during the process of exposure to radiation.

Operational Protocols

To study the UV-radiation effect (375 nm) on bacterium Escherichia coli E12 DNA reparation in microgravity conditions. The UV radiation camera contains a biological material in NaCl solution (0.9%), which is distributed by four grooves (by 1ml). UV light with a wave length of 375 nm is generated by light-emitting diodes. The bacteriological solution contains nonpathogenic bacteria, which are derivatives of Escherchia coli K12.

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Results/More Information

Biomaterials exposed to UV radiation and experimental data recorded in the memory module.

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Related Websites
  • Energia - Science Research on the ISS Russian Segment
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    image The experimental hardware includes three separate modules; irradiation module (UV radiation camera); electronic control module (with a set of cables) and ventilation module.
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    Information provided by the investigation team to the ISS Program Scientist's Office.
    If updates are needed to the summary please contact JSC-ISS-Program-Science-Group. For other general questions regarding space station research and technology, please feel free to call our help line at 281-244-6187 or e-mail at JSC-ISS-Research-Helpline.