Study of the Effects of Spaceflight Factors on the Technological and Biomedical Characteristics of Bifidobacteria (Bif) - 03.07.18

Overview | Description | Applications | Operations | Results | Publications | Imagery

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Science Objectives for Everyone
The Study of the Effects of Spaceflight Factors on the Technological and Biomedical Characteristics of Bifidobacteria (Bif) investigation identifies the specifics of metabolism and morphology of different phenotypes of one strain of the Bifidobacteria caused by microgravity in order to obtain probiotics with improved biomedical properties and to increase the efficiency of production.
Science Results for Everyone
Information Pending

The following content was provided by I. V. Nyn, G. Y. Scherbakov, M.D., and is maintained in a database by the ISS Program Science Office.
Experiment Details

OpNom:

Principal Investigator(s)
I. V. Nyn, Biopreparat, Russia
G. Y. Scherbakov, M.D., Biopreparat, Russia

Co-Investigator(s)/Collaborator(s)
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Developer(s)
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Sponsoring Space Agency
Russian Federal Space Agency (Roscosmos)

Sponsoring Organization
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Research Benefits
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ISS Expedition Duration
October 2009 - September 2010; March 2011 - May 2012; September 2012 - September 2013

Expeditions Assigned
21/22,23/24,27/28,29/30,33/34,35/36

Previous Missions
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Experiment Description

Research Overview
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Description
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Applications

Space Applications
The spaceflight factors may only serve as the main starting point for selecting organisms with modified properties. Subsequent work with them on Earth may assist scientists in obtaining technologically important material.

Earth Applications
A comparative analysis of the morpho-physiological dissociation of the bifidobacteria on Earth and in microgravity, assuming appropriate procedures, facilitates identification of the specifics of metabolism and morphology of different phenotypes of one strain, which provide new opportunities to raise the efficiency of producing bifido-containing probiotics with improved biomedical characteristics.

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Operations

Operational Requirements and Protocols
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Decadal Survey Recommendations

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Results/More Information

Bif utilized the Bifidobacterium bifidum 1 and Bifidobacterium adolescentis МС-42 strains to observe onboard the ISS. Bif showed once again that microorganisms undergo phenotypic changes during cultivations under the influence of different environmental factors. The obtained results confirm that possibly, the changes in microorganisms’ activity types, which occur on board of a space vehicle under condition of microgravity are not often due to genetic or chromosomal mutations. And these are the very ones that define the stability of the newly obtained properties of organisms and transmission of these properties from generation to generation. Spaceflight factors, the most significant of which, microgravity, impossible to simulate on Earth, may serve only as the most important starting point for the selection of organisms with modified properties. Subsequent work with them on the ground may assist scientists in obtaining technologically important material.

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Related Websites
Energia - Science Research on the ISS Russian Segment

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Imagery