Dynamics of the Main Factors of Cardiac Function, of Central and Regional Circulation in Rest and During the Influence of Lower Body Negative Pressure (Cardio-ODNT) - 11.22.16
Cardio-ODNT (Cardio-Lower Body Negative Pressure) is a medical investigation designed to determine the condition of the cardiovascular system in the lower extremities. Cardio-ODNT uses a pneumatic-vacuum suit to produce a negative pressure to the extremities while physical load is being produced by the cosmonaut. Science Results for Everyone
These pants are tight for a good reason. Space station crewmembers wore a lower body negative pressure suit to evaluate cardiac activity and circulation in the legs in microgravity. The results clarified microgravity’s effect on blood vessels in the legs and showed which regions of the body are most affected by long-term exposure. Using the suit to apply negative pressure to the legs during flight had positive effects on circulation throughout the body, but particularly in the pulmonary region, which is most affected by microgravity. Results indicated that sessions in the pressure suit will be useful in helping prepare crewmembers for return to Earth. Experiment Details
Valery V. Bogomolov, M.D., Ph.D., Institute for Biomedical Problems, Moscow, Russia
Sponsoring Space Agency
Russian Federal Space Agency (Roscosmos)
ISS Expedition Duration
October 2004 - April 2005; October 2005 - April 2006; September 2006 - October 2008
Investigation of dynamics of basic factors of cardiac activity and blood circulation.
Operational Requirements and Protocols
Investigation of responses of big and small circles of blood circulation when negative pressure affects the lower part of the body and the dependence of these responses on the initial status of the cardiovascular system.
Decadal Survey Recommendations
Information Pending^ back to top
Prediction of a cosmonauts' cardiovascular system state.^ back to top
Turchaninova VF, Alferova IV, Krivolapov VV, Liamin VR, Beliaev AP. Dependence of the circulation system functioning on cosmonaut age according to the results of physical loading tests on a veloergometer. Human Physiology. 2013 December 29; 39(7): 707-711. DOI: 10.1134/S0362119713070189. [
Original Russian Text © V.F. Turchaninova, I.V. Alferova, V.V. Krivolapov, V.R. Liamin, A.P. Beliaev, 2010, published in Aviakosmicheskaya i Ekologicheskaya Meditsina, 2010, Vol. 44, No. 5, pp. 8–12.]
Turchaninova VF, Alfyorova IV, Krivolapov VV. Several aspects of a comparative analysis of hemodynamic reactions to LBNP in crewmembers from various age groups. Aviakosmicheskaia i Ekologicheskaia Meditsina (Aerospace and Environmental Medicine). 2010; 44(1): 20-25. DOI: 10.1134/S0362119712070249. [Also: Turchaninova, V. F., I. V. Alferova, and V. V. Krivolapov, ‘Some Aspects of the Comparative Analysis of Hemodynamic Responses to LBNP Tests in Cosmonauts of Different Age Groups’, Human Physiology, 38 (2012), 721–26 http://dx.doi.org/10.1134/S0362119712070249 ]
Kotovskaya AR, Fomina GA. Human venous hemodynamics in microgravity and prediction of orthostatic tolerance in flight. Human Physiology. 2015 December 22; 41(7): 699-703. DOI: 10.1134/S0362119715070063. PMID: 23700615. [Russian. Original Russian Text © A.R. Kotovskaya, G.A. Fomina, 2013, published in Aviakosmicheskaya i Ekologicheskaya Meditsina, 2013, Vol. 47, No. 1, pp. 37–42.]
Ground Based Results Publications
Energia - Science Research on the ISS Russian Segment
Chibis pneumatic-vacuum suit. Image courtesy of Russian Space Agency (FSA).
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Gamma-1M hardware. Image courtesy of Russian Space Agency (FSA).
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