NASA - National Aeronautics and Space Administration

-- Deep Space ICCHIBAN: An International Comparison of Space Radiation Dosimeters aboard the NASA Deep Space Test Bed, (Principal Investigator (PI): Eric Benson, Eril Research Inc, San Rafael, Calif., $175,000)

-- Inflammation in the Brain after Particulate Irradiation Predisposes the Hippocampus to a Heightened Vulnerability after a Secondary Insult, (PI: John Fike, University of California, San Francisco, San Francisco, Calif., $1.1M)

-- Simulated Microgravity and Radiation-Induced Bone Degeneration: Oxidative Stress- and p53-Dependent Mechanisms, (PI: Ruth Globus, NASA Ames Research Center, Moffett Field, Calif., $1.56M)

-- Measurements of Fragmentation Cross Sections and Particle Spectra For Galactic Cosmic Ray-Like Nuclei between 3 and 10 GeV/nucleon at the BNL AGS, (PI: Jack Miller, Lawrence Berkeley National Laboratory, Berkeley, Calif., $307,000)

-- Effect of Space Radiation on Degenerative Tissue Disease, Genetic Instability and Oxidative DNA Damage in Ataxia Telangiectasia Deficient Mice, (PI: Robert Schiestl, University of California, Los Angeles, Los Angeles, Calif., $1.2M)

-- A Role for Homologous Recombination in Complex DSB Repair after HZE Particles, (PI: Claudia Wiese, Lawrence Berkeley National Laboratory, Berkeley, Calif., $1.2M)

-- Determination of Radiation Shielding Effectiveness using a Tissue Equivalent Proportional Counter to Measure Dose and Quality Factors, (PI: Thomas Borak, Colorado State University, Fort Collins, Colo., $637,000)

-- Shielding Solutions-Novel Shielding and Multi-Functional Thermal and Structural Materials, (PI: Janine Thorton, Lockheed Martin Space Systems, Littleton, Colo., $600,000)

-- Solid Hydrogen Radiation Shield Testing, (PI: Stephen Bates, Thoughtventions Unlimited LLC, Glastonbury, Conn., $712,000)

-- High Performance Polymer Nanocomposites for Radiation Shielding, (PI: Julie Harmon, University of South Florida, Tampa, Fla., $588,000)

-- Effects of Estrogen on Cataract Induction After Exposure to High LET Radiation, (PI: Joseph Dynlacht, Indiana University, Indianapolis, Ind., $1.4M)

-- Cross Sections for HZE Transport Calculations, (PI: John Wefel, Louisiana State University, Baton Rouge, La., $600,000)

-- Ionizing Radiation and its Effects on Cardiovascular Function in the Context of Space Flight, (PI: Dan Berkowitz, The Johns Hopkins University, School of Medicine, Baltimore, Md., $1.2M)

-- Mitigating High Z Radiation induced Genomic Instability by Non-Protein Thiols, (PI: William Morgan, University of Maryland, Baltimore, Baltimore, Md., $1.1M)

-- Human Endothelial Cells in 2-D and 3-D Systems; Non-Cancer Effects and Space-Related Radiations, (PI: Charles Geard, Columbia University, New York, N.Y., $1.2M)

-- Mechanisms of Ocular Cataracts, (PI: Eric Hall, Columbia University, New York, N.Y., $1.2M)

-- Radiation Shielding Space Coatings: An Approach to In Space Application of Coatings, (PI: Mark Soucek, University of Akron, Akron, Ohio, $594,000)

-- Neurogenesis and Cognition in Human apoE Transgenic Mice following 56Fe Radiation, (PI: Jacob Raber, Oregon Health & Science University, Portland, Ore., $1.2M)

-- Molecular and Cellular Effects of Heavy Ion Fragmentation due to Shielding, (PI: Sandeep Burma, University of Texas Southwestern Medical Center, Dallas, Texas, $1.2M)

-- Weight Windows Variance Reduction Technique for the HETC Monte Carlo Code, (PI: Robert Singleterry, NASA Langley Research Center, Hampton, Va., $1.1M)

-- Multifunctional Hybrid Polymeric Materials for Radiation Shielding, (PI: Robert Orwoll, College of William and Mary, Williamsburg, Va., $449,000)