Technicians switched off Endeavour's displays and systems for the final time.
Update: NASA's 747 and Enterprise have landed in New York.
See photos of the flyover on NASA HQ's Flickr page.
Secured atop NASA's Shuttle Carrier Aircraft, space shuttle Discovery started its final journey with a sunrise takeoff at 7 a.m. EDT.
NASA 905 will support the last three shuttle ferry flights.
The best views in Virginia, Maryland and D.C. will be from the National Mall and near the Potomac River.
Imagine flying from Florida to D.C. with nowhere to sit, no A/C -- not even a bathroom. NASA kept two 747s set up this way on purpose.
Recently, NASA's space shuttles were on the move as part of the transition and retirement activities at Kennedy Space Center in Florida.
The "vehicle powered" light is turned off for the last time as two shuttle orbiters' flight decks go dark.
A groundbreaking ceremony officially launched construction of space shuttle Atlantis' future home at the Kennedy Space Center Visitor Complex.