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Soluble Protein Crystallization: Obtaining Crystals of Soluble Proteins FcgIII and FcgeII with a Perfect Crystal Structure (SPC)
03.22.12

Overview | Description | Applications | Operations | Results | Publications | Images

Experiment/Payload Overview

Information provided courtesy of the Energia website.
Brief Summary

Information Pending

Principal Investigator

  • , , University of Port Elizabeth, , , Russia

    • Co-Investigator(s)/Collaborator(s)

    Information Pending

    Payload Developer Information Pending

    Sponsoring Space Agency

    Roscosmos

    Sponsoring Organization:

    Information Pending

    ISS Expedition Duration:

    December 2001 - June 2002



    Expeditions Assigned

    4

    Previous ISS Missions

    Information Pending

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    Experiment/Payload Description

    Research Summary

    Information Pending

    Description

    Obtaining crystals of soluble proteins FcgIII and FcgeII with a highly perfect crystal structure.

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    Applications

    Space Applications

    Information Pending

    Earth Applications

    Information Pending

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    Operations

    Operational Requirements

    CPCF-2 module for accommodating 8 experimental reactors, where the processes of protein preparation growth are implemented, thermal insulation container for passive thermostatting CPCF-2 during delivery and return to Earth, activation mechanism for activating/deactivating crystallization processes in experimental reactors placed inside a sealed CPCF-2 module.

    Operational Protocols

    Obtaining high-quality protein monocrystals that are needed for ground X-ray structure analysis with high resolution.

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    Results/More Information

    The result of the space experiment is a CPCF-2 module with crystals grown in zero gravity. X-ray structure analysis of protein crystals obtained in space flight will be used in developing in developing a new generation of drugs.

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    Related Web Sites
  • Energia - Science Research on the ISS Russian Segment

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    Publications

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    Ground Based Results Publications

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    ISS Patent Publications

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    Related Publications

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    Images

    imageCPCF-2 module with thermal insulators.


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    Information provided by the investigation team to the ISS Program Scientist's Office.
    If updates are needed to the summary please contact JSC-ISS-Program-Science-Group. For other general questions regarding space station research and technology, please feel free to call our help line at 281-244-6187 or e-mail at JSC-ISS-Payloads-Helpline.
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