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Overview | Description | Applications | Operations | Results | Publications | Imagery

Facility Overview


Brief Facility Summary

NanoRacks Plate Reader is a laboratory instrument designed to detect biological, chemical or physical events of samples in microtiter plates. Microplate readers are widely used in research, drug discovery, bioassay validation, quality control and manufacturing processes in the pharmaceutical and biotechnological industry and academic organizations.

Facility Manager(s)

Michael Johnson, NanoRacks, LLC, Houston, TX, United States

Co-Facility Manager(s)

Information Pending

Facility Developer(s)

NanoRacks, LLC, Houston, TX, United States

Sponsoring Agency

National Aeronautics and Space Administration (NASA)

Expeditions Assigned

29/30,31/32,33/34,35/36

Previous ISS Missions

Information Pending

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Facility Description

Facility Overview

• NanoRacks Plate Reader is a modified SpectraMax® M5e Multi-Mode Microplate Reader.



• The SpectraMax® M5e Micoplate Reader is the standard for UV/Visible multi-mode reader absorbance, providing ultrafast, full spectral range detection for cuvettes.



• NanoRacks Plate Reader possesses five modes, UV-Visible Absorbance, Fluorescence Intensity, Time-Resolved Fluorescence, Fluorescence Polarization, and Glow Luminescence, providing the benefit of multiple detection modes in one platform.

Description

NanoRacks Plate Reader is a modified SpectraMax® M5e Multi-Mode Microplate Reader. The SpectraMax® M5e Multi-Mode Microplate Reader is the standard for UV/Visible multi-mode reader absorbance, providing ultrafast, full spectral range detection for cuvettes, 96-well, and 384-well microplates.

Using the patented PathCheck® Pathlength Measurement Technology, the SpectraMax M5e Microplate Reader transforms each well in a microplate to a fixed optical pathlength cuvette. This temperature-independent normalization corrects for varying well volumes and can eliminate standard curves by allowing the calculation of concentrations directly from the absorbance with a known extinction coefficient, as exemplified with nucleic acid and protein quantitation.

For fluorescence intensity, time resolved fluorescence, and fluorescence polarization assays, the optical design provides the highest level of flexibility. Users can select from top or bottom read modes for improved sensitivity for solution and cell-based assays. Assays can be better optimized by scanning across a range of wavelengths in increments as small as 1 nm. Up to 4 wavelength pairs can be read in one protocol for endpoint and kinetic measurements.

For luminescence, the NanoRacks Plate Reader utilizes a dedicated luminescence photomultiplier tube (PMT), providing the user the maximum signal and lowest background possible for glow luminescence reporter gene assays.

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Operations

Facility Operations

Information Pending

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Results/More Information

Information Pending

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Availability

Information Pending

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Results Publications

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Ground Based Results Publications

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ISS Patents

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Related Publications

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Related Websites

NanoRacks LLC

Molecular Devices

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Imagery

NASA Image: ISS034E005601 -

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NASA Image: ISS034E005602

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