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Production of Hight Quality Crystals of Interleukin -1Alpha, -1Beta and Receptor of Antagonist of Interleukin-1 (Interleukin-K)
12.05.12

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Overview | Description | Applications | Operations | Results | Publications | Imagery

Experiment Overview

This content was provided by G. Y. Scherbakov, M.D., and is maintained in a database by the ISS Program Science Office.

Brief Summary

Information Pending

Principal Investigator(s)

  • G. Y. Scherbakov, M.D., Russia
  • Co-Investigator(s)/Collaborator(s)

    Information Pending

    Developer(s)
    Information Pending

    Sponsoring Space Agency

    Russian Federal Space Agency (Roscosmos)

    Sponsoring Organization

    Information Pending

    ISS Expedition Duration:

    October 2003 - April 2009



    Expeditions Assigned

    8,9,10,11,13,14,15,16,18

    Previous ISS Missions

    Information Pending

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    Experiment Description

    Research Overview

    Information Pending

    Description

    Production of crystals of interleukins-1 alpha, -1 beta and receptor antagonist of interleukin-1 under space flight conditions, which are suitable for x-ray crystal analysis.

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    Applications

    Space Applications

    Information Pending

    Earth Applications

    Information Pending

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    Operations

    Operational Requirements

    Luch-2 equipment accommodating multipurpose crystallization cassettes, Thermal insulating container Biokont-T for transportation of the Luch-2 equipment, Temperature-stable container "AQUA 01".

    Operational Protocols

    Development of the procedure for interleukin crystallization under orbital flight conditions. Production of interleukin crystals that are larger in size and the structure of which is more ordered as compared with the crystals grown on the ground.

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    Results/More Information

    Peptides carrying the main protein properties with no adverse effects produced can be synthesized.

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    Related Websites
  • Energia - Science Research on the ISS Russian Segment
  • Coordinating Scientific and Technical Council of the Russian Space Agency [Russian]
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    Imagery

    image Luch-2 equipment accommodating multipurpose crystallization cassettes.
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    image Thermal insulating container Biokont-T for transportation of the Luch-2 equipment.
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    image Temperature-stable container "AQUA 01".
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    Information provided by the investigation team to the ISS Program Scientist's Office.
    If updates are needed to the summary please contact JSC-ISS-Program-Science-Group. For other general questions regarding space station research and technology, please feel free to call our help line at 281-244-6187 or e-mail at JSC-ISS-Payloads-Helpline.