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Production of Hight Quality Crystals of Interleukin -1Alpha, -1Beta and Receptor of Antagonist of Interleukin-1 (Interleukin-K)
03.22.12

Overview | Description | Applications | Operations | Results | Publications | Images

Experiment/Payload Overview

Information provided courtesy of the Energia website.
Brief Summary

Information Pending

Principal Investigator

  • G. Y. Scherbakov, M.D., , , , Russia

    • Co-Investigator(s)/Collaborator(s)

    Information Pending

    Payload Developer Information Pending

    Sponsoring Space Agency

    Roscosmos

    Sponsoring Organization:

    Information Pending

    ISS Expedition Duration:

    October 2003 - April 2009



    Expeditions Assigned

    8, 9, 10, 11, 13, 14, 15, 16, 18

    Previous ISS Missions

    Information Pending

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    Experiment/Payload Description

    Research Summary

    Information Pending

    Description

    Production of crystals of interleukins-1 alpha, -1 beta and receptor antagonist of interleukin-1 under space flight conditions, which are suitable for x-ray crystal analysis.

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    Applications

    Space Applications

    Information Pending

    Earth Applications

    Information Pending

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    Operations

    Operational Requirements

    Luch-2 equipment accommodating multipurpose crystallization cassettes, Thermal insulating container Biokont-T for transportation of the Luch-2 equipment, Temperature-stable container "AQUA 01".

    Operational Protocols

    Development of the procedure for interleukin crystallization under orbital flight conditions. Production of interleukin crystals that are larger in size and the structure of which is more ordered as compared with the crystals grown on the ground.

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    Results/More Information

    Peptides carrying the main protein properties with no adverse effects produced can be synthesized.

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    Related Web Sites
  • Energia - Science Research on the ISS Russian Segment
  • Coordinating Scientific and Technical Council of the Russian Space Agency [Russian]

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    Publications

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    Ground Based Results Publications

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    ISS Patent Publications

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    Related Publications

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    Images

    imageTemperature-stable container "AQUA 01".


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    imageLuch-2 equipment accommodating multipurpose crystallization cassettes.


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    imageThermal insulating container Biokont-T for transportation of the Luch-2 equipment.


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    Information provided by the investigation team to the ISS Program Scientist's Office.
    If updates are needed to the summary please contact JSC-ISS-Program-Science-Group. For other general questions regarding space station research and technology, please feel free to call our help line at 281-244-6187 or e-mail at JSC-ISS-Payloads-Helpline.
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