Investigation of the Osteoclastic and Osteoblastic Responses to Microgravity Using Goldfish Scales (Fish_Scales)
12.05.12
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Experiment Overview
This content was provided by Nobuo Suzuki, Ph.D., and is maintained in a database by the ISS Program Science Office.
Information provided courtesy of the Japan Aerospace and Exploration Agency (JAXA).
Brief Summary
Investigation of the Osteoclastic and Osteoblastic Responses to Microgravity Using Goldfish Scales (Fish Scales) will examine regenerating scales collected from anesthetized goldfish in microgravity using the Cell Biology Experiment Facility (CBEF); the results will be compared with ground controls.
Principal Investigator(s)
Nobuo Suzuki, Ph.D., Kanazawa University, Kanazawa, Japan
Co-Investigator(s)/Collaborator(s)
Information Pending
Developer(s)
Information Pending
Sponsoring Space Agency
Japan Aerospace Exploration Agency (JAXA)
Sponsoring Organization
Information Pending
ISS Expedition Duration
March 2010 - September 2010
Expeditions Assigned
23/24
Previous ISS Missions
Fish Scales is scheduled for its first operations on ISS Increment 23/24.
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Experiment Description
Research Overview
- In mammals bone is formed and maintained by continuous remodeling through bone resorption by resorptive cells, i.e., osteoclasts, and subsequent new bone formation by formative cells, i.e., osteoblasts.
- Regulation of Bone Metabolism in Space: Analysis by an in vitro Assay System Using Goldfish Scale as a Model of Bone (Fish Scales) uses osteoblasts and osteoclasts in the regenerating scales of goldfish to examine the effect of microgravity on bone metabolism.
Description
Information Pending
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Applications
Space Applications
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Earth Applications
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Operations
Operational Requirements
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Operational Protocols
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Results/More Information
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Related Websites
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Imagery