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Early Detection of Osteoporosis in Space (EDOS)
05.16.12

Overview | Description | Applications | Operations | Results | Publications | Images

Experiment/Payload Overview

Information provided courtesy of the Erasmus Experiment Archive.
Brief Summary

Early Detection of Osteoporosis in Space (EDOS) tests the ability of XtremeCT technology to detect bone architecture changes and provide a better evaluation of the kinetics of bone loss recovery postflight.

Principal Investigator

  • Christian Alexandre, M.D., Universite Jean Monnet, St. Etienne, , France

    • Co-Investigator(s)/Collaborator(s)

  • Bruno Koller, , SCANCO Medical, Bassesdorf, , Switzerland
  • L. Braak, , , , , France
  • Laurence Vico, Ph.D., Universite Jean Monnet, St. Etienne, , France
  • Martina A. Heer, Ph.D., University of Bonn, Bonn, , Germany
  • Mohamed Zouch, , Universite Jean Monnet, St. Etienne, , France
  • Peter Ruegsegger, , Swiss Federal Institute of Technology, Space Biology, Zurich, , Switzerland

    • Payload Developer

    SCANCO Medical, Bassesdorf, , Switzerland

    Sponsoring Space Agency

    European Space Agency (ESA)

    Sponsoring Organization:

    Information Pending

    ISS Expedition Duration:

    April 2007 - May 2012



    Expeditions Assigned

    15, 16, 17, 18, 19/20, 21/22, 29/30

    Previous ISS Missions

    EDOS began ISS operations on Expedition 16.

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    Experiment/Payload Description

    Research Summary

    • Early Detection of Osteoporosis in Space (EDOS) will demonstrate the efficiency of the three-dimensional peripheral quantitative computed tomography (3DpQCT) technique (XtremeCT developed by SCANCO Medical) for an early detection of bone remodeling impairment and of the related bone microarchitecture changes and to provide information on the kinetics of bone loss. Ultimately the objective is to show if this device could provide an accurate measurements to evaluate the efficiency of bone countermeasures following missions in microgravity.


    • The XtremeCT allows three-dimensional imaging of bone microarchitecture with a high resolution.


    • EDOS evaluates the XtremeCT with preflight and postflight measurements in a series of flights. Measurements will include XtremeCT, Dual-energy X-ray absorptiometry (DEXA) and analysis of bone markers (blood samples).

    Description

    Information Pending

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    Applications

    Space Applications

    Information Pending

    Earth Applications

    Information Pending

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    Operations

    Operational Requirements

    Information Pending

    Operational Protocols

    Information Pending

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    Results/More Information

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    Related Web Sites
  • Columbus Mission - European Experiment Programme
  • SCANCO Medical

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    Publications

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    Ground Based Results Publications

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    ISS Patent Publications

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    Related Publications

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    Images

    imageXtreme CT hardware. Image provide courtesy of SCANCO Medical.


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    Information provided by the investigation team to the ISS Program Scientist's Office.
    If updates are needed to the summary please contact JSC-ISS-Program-Science-Group. For other general questions regarding space station research and technology, please feel free to call our help line at 281-244-6187 or e-mail at JSC-ISS-Payloads-Helpline.
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