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Development of Methods for Designing New Recombinants Producing Strains of Bacteria in Space Flight (Conjugation)
03.22.12

Overview | Description | Applications | Operations | Results | Publications | Images

Experiment/Payload Overview

Information provided courtesy of the Energia website.
Brief Summary

Kon'yugatsiya (Conjugation) studies the exchange of genetic material in microgravity in order to develop strains that can produce new target proteins.

Principal Investigator

  • Y. N. Sventitsky, , , , , Russia

    • Co-Investigator(s)/Collaborator(s)

    Information Pending

    Payload Developer Information Pending

    Sponsoring Space Agency

    Roscosmos

    Sponsoring Organization:

    Information Pending

    ISS Expedition Duration:

    April 2003 - March 2010



    Expeditions Assigned

    7, 9, 10, 12, 13, 14, 15, 16, 17, 18, 19/20, 21/22

    Previous ISS Missions

    Information Pending

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    Experiment/Payload Description

    Research Summary

    Information Pending

    Description

    Development of the methods for designing new recombinant producing strains which are essential for protein medicine by means of the bacterial conjugation and plasmid mobilization technique during space flight.

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    Applications

    Space Applications

    Information Pending

    Earth Applications

    Information Pending

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    Operations

    Operational Requirements

    Thermal insulating container Biokont-T, Recomb-K equipment, Thermostatically controlled container 'Akvarius', Cryogem-03 refrigerator.

    Operational Protocols

    Study the conjugations of different proteins in the microgravity environment.

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    Results/More Information

    As follows from the experimental results, it is planned to select optimal conditions for genetic material transfer during bacterial conjugation and protoplast fusion under orbital flight conditions with a maximum output of new recombinant producing strains, which are essential for protein medicine. The developed procedure will be used to create new producing strains of biologically active substances intended for manufacturing medicines.

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    Related Web Sites
  • Energia - Science Research on the ISS Russian Segment

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    Publications

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    Ground Based Results Publications

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    ISS Patent Publications

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    Related Publications

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    Images

    imageThermal insulating container 'Biokont-T', Recomb-K equipment, thermostatically controlled container 'Akvarius'.


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    Information provided by the investigation team to the ISS Program Scientist's Office.
    If updates are needed to the summary please contact JSC-ISS-Program-Science-Group. For other general questions regarding space station research and technology, please feel free to call our help line at 281-244-6187 or e-mail at JSC-ISS-Payloads-Helpline.
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