OpNom: SprintExperiment Overview
Integrated Resistance and Aerobic Training Study (Sprint) evaluates the use of high intensity, low volume exercise training to minimize loss of muscle, bone, and cardiovascular function in ISS crewmembers during long-duration missions.Principal Investigator(s)
Johnson Space Center, Human Research Program, Houston, TX, United States
National Aeronautics and Space Administration (NASA)Sponsoring Organization
Human Exploration and Operations Mission Directorate (HEOMD)Research Benefits
Information PendingISS Expedition Duration:
March 2011 - September 2014Expeditions Assigned
27/28,29/30,31/32,33/34,35/36,37/38,39/40Previous ISS Missions
ISS Science Challenge Selected Project
We picked Sprint because we thought it looked very interesting. We learned that it protects from bone and muscle loss. It helps the heart function. We think it is very useful for the ISS Crew Members.
-Liam, Blade, Carson, Dalton and Bryce, Grade 6, Madison Elementary School, Massena, New York
Current exercise countermeasures on the International Space Station (ISS) are insufficient to prevent muscle atrophy, cardiovascular deconditioning and bone loss associated with long-duration space flight. Despite crew allocation of approximately 2.5 hours per day to exercise, decrements in fitness are observed following flights averaging 180 days in duration. Muscle strength is decreased 11% to 17%, muscular endurance approximately 10% and bone mineral density 2% to 7%. There is a need to prevent spaceflight-related deconditioning to protect the health and mission readiness of current ISS crew as well as to enable NASA to protect fitness of even longer duration crewmembers for the Moon and Mars missions. Investigator’s long range goal in the Exercise Physiology and Countermeasures Project is to develop and optimize exercise countermeasures for use in long-duration spaceflights. Investigators utilize ISS as a platform and laboratory with the ultimate goal of supporting increasingly longer duration space exploration missions; therefore, this research benefits both ISS crew and future crewmembers on even longer missions such as the Moon and Mars. The objective of the current proposal is to evaluate a new exercise prescription using new exercise hardware on ISS. The new Integrated Resistance and Aerobic Training Study (Sprint) protocol uses an evidence based approach to develop a higher intensity, lower duration exercise program utilizing ISS exercise hardware: the Advanced Resistance Exercise Device (ARED) and a second generation treadmill, Combined Operational Load Bearing External Resistance Treadmill (COLBERT). Accordingly, Sprint differs from standard care primarily on the increased intensity and decreased total exercise time. The effectiveness of Sprint is determined by comparison of pre- and post-flight measurements of muscle, cardiovascular and bone health against two other groups. The comparison groups include crewmembers who perform the standard care exercise prescription utilizing the newly designed exercise hardware (ARED & COLBERT), and a historic data set of those who used a standard care exercise prescription using the old exercise hardware.
Upon completion of this study, investigators expect to provide an integrated resistance and aerobic exercise training protocol capable of maintaining muscle, bone and cardiovascular health while reducing total exercise time over 180 days of spaceflight. This will provide invaluable information in support of the investigator’s long-term goal of protecting human fitness for longer space exploration missions.
Upon completion of this study, investigators expect to provide an integrated resistance and aerobic exercise training protocol capable of maintaining muscle, bone and cardiovascular health while reducing total exercise time over 180 days of space flight. This will provide invaluable information in support of investigator’s long term goal of protecting human fitness for even longer space exploration missions.Earth Applications
Data gathered from the Sprint investigation may help scientists develop/enhance aerobic training and resistance protocols that may be used on Earth to aid in muscle, bone and cardiovascular health.
The Sprint experiment requires a count of 20 active and 20 control subjects. The active subjects perform all aspects of the protocol, but the control subjects only perform the pre- and post-flight data collections, and consent to sharing of exercise data. VO2max data collections are performed monthly in flight starting with FD 14. Ultrasound scans are on FD 14, 30, 60, 90, 120, 150, and R-7. There is a requirement for real-time data downlink during the VO2max measurement and remote guidance for all ultrasound scans. Subject specific exercise prescriptions are uploaded weekly and actual exercise data downlinked weekly.Operational Protocols
In-flight monitoring of training loads on ARED and COLBERT are evaluated as assessment of muscle function. Cardiovascular fitness includes a monthly measurement of VO2max, heart rate (HR) response to submaximal exercise, ventilatory threshold, left ventricular (LV) mass and contractility. Monthly ultrasound scans of the thigh and calf are used to evaluate spaceflight-induced changes in the muscle volume. Subjects perform the new Sprint exercise prescription in flight, six days per week, beginning as early as possible; preferably on the first full in flight day. The first two weeks in flight are an acclimation period of reduced training intensity and volume; after week two, the full training begins. The early onset of training is an important evidence-based aspect of Sprint for prevention of the initial deconditioning that can occur in the first 30 days of unloading in the absence of any exercise program.