Bacterial Acclimation and Adaptation to the Space Environment Conditions-A (BASE-A) - 07.14.16
The BASE-A investigation will study the effect of microgravity on bacteria and how bacteria adapts to the microgravity environment on ISS. The data provided by this investigation will give scientists valuable insight into how basic organisms adapt to new environments. This information could prove valuable when planning future long duration expeditions to the Moon and Mars. Science Results for Everyone
Bacteria are leading the way in adapting to living in space. Scientists looked at how bacteria cope and adapt to different conditions of space flight such as weightlessness, cosmic radiation, space electromagnetism, and space vibrations. Results show that growth, spontaneous mutation, and numbers of bacteria on the station behaved similarly to ground experiments. Some proteins involved in metabolism were more active in space, and it was demonstrated for the first time that low-dose space radiation can change the activity of some genes. Further studies on the effects of low-dose ionizing radiation on bacteria could assess how adaptation might affect space habitat contamination, crew health, waste recycling, and food production systems. Experiment Details
Natalie Leys, M.D., Belgium Nuclear Research Center, Boeretang, Belgium
Pieter Cornelis, M.D., Flanders Institute for Biotechnology, Brussels, Belgium
Ruddy Wattiez, University of Mons-Hainaut, Mons, Belgium
Martina A. Heer, Ph.D., University of Bonn, Bonn, Germany
Max Mergeay, D.Sc., Belgium Nuclear Research Center, Mol, Belgium
Belgian Nuclear Research Centre, Mol, Belgium
Sponsoring Space Agency
European Space Agency (ESA)
ISS Expedition Duration
September 2006 - April 2007
- The BASE-A investigation will provide confirmation and analysis of previous observations on short duration mission in microgravity.
- The BASE-A investigation will allow the comparison of response of multiple bacteria under similar culturing conditions in space.
In the BASE-A (Bacterial Adaptation to Space Environments-A) experiment, the science team will study how bacteria cope and adapt to the different space flight environmental parameters (e.g. weightlessness, cosmic radiation, space electromagnetism, space vibrations). Based on these results, scientists will try to assess how such adaptations might influence their potential to contaminate and biodeteriorate the space habitat, their potential to endanger crew health, or their function in waste recycling or food production systems. In the BASE project, scientists will also study the physiology, gene expression, gene rearrangement and gene transfer of cultures of several model bacteria grown under microgravity and other space flight conditions.
Operational Requirements and Protocols
Decadal Survey Recommendations
Information Pending^ back to top
Leys N, Baatout S, Rosier C, Dams A, s'Heeren C, Wattiez R, Mergeay M. The response of Cupriavidus metallidurans CH34 to spaceflight in the international space station. Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology. 2009 August 1; 96(2): 227-245. DOI: 10.1007/s10482-009-9360-5. PMID: 19572210.
Mastroleo F, Van Houdt R, Leroy B, Benotmane M, Janssen A, Mergeay M, Vanhavere F, Hendrickx L, Wattiez R, Leys N. Experimental design and environmental parameters affect Rhodospirillum rubrum S1H response to space flight. International Society for Microbial Ecology. 2009; 3(12): 1402-1419. DOI: 10.1038/ismej.2009.74. PMID: 19571896.
Vanhavere F, Genicot JL, O'Sullivan D, Zhou D, Spurny F, Jadrnickova I, Sawakuchi G, Yukihara EG. DOsimetry of BIological EXperiments in SPace (DOBIES) with luminescence (OSL and TL) and track etch detectors. Radiation Measurements. 2008 February; 43(2-6): 694-697. DOI: 10.1016/j.radmeas.2007.12.002.
Ground Based Results Publications
The information on this page is provided courtesy of the ESA Erasmus Experiment Archive.
The information provided is courtesy of the ESA Astrolab Mission web page.
Example of Kubik incubator with centrifuge configuration loaded with experiment containers. Image courtesy of ESA.
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