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Bacterial Acclimation and Adaptation to the Space Environment Conditions-A (BASE-A)
04.26.13

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Overview | Description | Applications | Operations | Results | Publications | Imagery

Experiment Overview

This content was provided by Max Mergeay, D.Sc., and is maintained in a database by the ISS Program Science Office.

Information provided courtesy of the Erasmus Experiment Archive.
Brief Summary

The BASE-A investigation will study the effect of microgravity on bacteria and how bacteria adapts to the microgravity environment on ISS. The data provided by this investigation will give scientists valuable insight into how basic organisms adapt to new environments. This information could prove valuable when planning future long duration expeditions to the Moon and Mars.

Principal Investigator(s)

  • Max Mergeay, D.Sc., Belgium Nuclear Research Center, Mol, Belgium

    • Co-Investigator(s)/Collaborator(s)

  • Martina A. Heer, Ph.D., Institute of Aerospace Medicine German Aerospace Center, Cologne, Germany
  • Natalie Leys, M.D., Belgium Nuclear Research Center, Boeretang, Belgium
  • Pieter Cornelis, M.D., Flanders Institute for Biotechnology, Brussels, Belgium
  • Ruddy Wattiez, University of Mons-Hainaut, Mons, Belgium

    • Developer(s)

    Belgian Nuclear Research Centre, Mol, , Belgium

    Sponsoring Space Agency

    European Space Agency (ESA)

    Sponsoring Organization

    Information Pending

    Research Benefits

    Information Pending

    ISS Expedition Duration

    September 2006 - April 2007

    Expeditions Assigned

    14

    Previous ISS Missions

    Information Pending

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    Experiment Description

    Research Overview

    • The BASE-A investigation will provide confirmation and analysis of previous observations on short duration mission in microgravity.


    • The BASE-A investigation will allow the comparison of response of multiple bacteria under similar culturing conditions in space.

    Description

    In the BASE-A (Bacterial Adaptation to Space Environments-A) experiment, the science team will study how bacteria cope and adapt to the different space flight environmental parameters (e.g. weightlessness, cosmic radiation, space electromagnetism, space vibrations). Based on these results, scientists will try to assess how such adaptations might influence their potential to contaminate and biodeteriorate the space habitat, their potential to endanger crew health, or their function in waste recycling or food production systems. In the BASE project, scientists will also study the physiology, gene expression, gene rearrangement and gene transfer of cultures of several model bacteria grown under microgravity and other space flight conditions.

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    Applications

    Space Applications

    Information Pending

    Earth Applications

    Information Pending

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    Operations

    Operational Requirements

    Information Pending

    Operational Protocols

    Information Pending

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    Results/More Information

    Test

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    Results Publications

       The response of Cupriavidus metallidurans CH34 to spaceflight in the international space station. Antonie van Leeuwenhoek. 2009; 96: 227-245. DOI: 10.1007/s10482-009-9360-5. PMID: 19572210.
      Jadrnickova I, Genicot JL, O'Sullivan D, Zhou D, Vanhavere F, Sawakuchi G, Yukihara EG, Spurny F.  DOsimetry of BIological EXperiments in SPace (DOBIES) with luminescence (OSL and TL) and track etch detectors. Radiation Measurements. 2008; 43(2-6): 694-697. DOI: 10.1016/j.radmeas.2007.12.002.
      Mastroleo F, Van Houdt R, Leroy B, Benotmane M, Janssen A, Vanhavere F, Mergeay M, Hendrickx L, Wattiez R, Leys N.  Experimental design and environmental parameters affect Rhodospirillum rubrum S1H response to space flight. International Society for Microbial Ecology. 2009; 3(12): 1402-1419. DOI: 10.1038/ismej.2009.74.

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    Ground Based Results Publications

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    ISS Patents

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    Related Publications

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    Related Websites
  • The information on this page is provided courtesy of the ESA Erasmus Experiment Archive.
  • The information provided is courtesy of the ESA Astrolab Mission web page.

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    Imagery

    image Example of Kubik incubator with centrifuge configuration loaded with experiment containers. Image courtesy of ESA.
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    image
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    Information provided by the investigation team to the ISS Program Scientist's Office.
    If updates are needed to the summary please contact JSC-ISS-Program-Science-Group. For other general questions regarding space station research and technology, please feel free to call our help line at 281-244-6187 or e-mail at JSC-ISS-Research-Helpline.
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