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Investigation of the Osteoclastic and Osteoblastic Responses to Microgravity Using Goldfish Scales (Fish Scales)
04.26.13

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Overview | Description | Applications | Operations | Results | Publications | Imagery

Experiment Overview

This content was provided by Nobuo Suzuki, Ph.D., and is maintained in a database by the ISS Program Science Office.

Information provided courtesy of the Japan Aerospace and Exploration Agency (JAXA).
Brief Summary

Investigation of the Osteoclastic and Osteoblastic Responses to Microgravity Using Goldfish Scales (Fish Scales) will examine regenerating scales collected from anesthetized goldfish in microgravity using the Cell Biology Experiment Facility (CBEF); the results will be compared with ground controls.

Principal Investigator(s)

  • Nobuo Suzuki, Ph.D., Kanazawa University, Kanazawa, Japan
  • Co-Investigator(s)/Collaborator(s)

    Information Pending

    Developer(s)
    Information Pending

    Sponsoring Space Agency

    Japan Aerospace Exploration Agency (JAXA)

    Sponsoring Organization

    Information Pending

    Research Benefits

    Information Pending

    ISS Expedition Duration

    March 2010 - September 2010

    Expeditions Assigned

    23/24

    Previous ISS Missions

    Fish Scales is scheduled for its first operations on ISS Increment 23/24.

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    Experiment Description

    Research Overview

    • In mammals bone is formed and maintained by continuous remodeling through bone resorption by resorptive cells, i.e., osteoclasts, and subsequent new bone formation by formative cells, i.e., osteoblasts.


    • Regulation of Bone Metabolism in Space: Analysis by an in vitro Assay System Using Goldfish Scale as a Model of Bone (Fish Scales) uses osteoblasts and osteoclasts in the regenerating scales of goldfish to examine the effect of microgravity on bone metabolism.

    Description

    Information Pending

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    Applications

    Space Applications

    Information Pending

    Earth Applications

    Information Pending

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    Operations

    Operational Requirements

    Information Pending

    Operational Protocols

    Information Pending

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    Results/More Information

    Information Pending

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    Related Websites

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    Imagery

    Information provided by the investigation team to the ISS Program Scientist's Office.
    If updates are needed to the summary please contact JSC-ISS-Program-Science-Group. For other general questions regarding space station research and technology, please feel free to call our help line at 281-244-6187 or e-mail at JSC-ISS-Research-Helpline.