Integrated Assessment of Long-term Cosmic Radiation Through Biological Responses of the Silkworm, Bombyx mori, in Space (RadSilk) - 12.03.13
Science Objectives for Everyone
Integrated Assessment of Long-term Cosmic Radiation Through Biological Responses of the Silkworm, Bombyx mori, in Space (RadSilk) examines the effects of radiation exposure in microgravity on silkworms.
Science Results for Everyone
Japan Aerospace Exploration Agency (JAXA), Tsukuba, , Japan
Japan Aerospace Exploration Agency (JAXA)Sponsoring Organization
Information PendingResearch Benefits
Information PendingISS Expedition Duration
October 2009 - March 2010Expeditions Assigned
21/22Previous ISS Missions
The silkworm eggs were investigated by the PI in STS-84
- The eggs of the silkworm (Bombyx mori) are used as an indicator for monitoring biological responses to long-term cosmic radiation in microgravity.
Eggs of silkworm Bombyx mori on the Earth in the customized egg cases. After the launch at 5 degrees C, the eggs are kept cooled in MELFI at 2 degrees C for diapause. A day before recovery STS docking, eggs are incubated using CBEF at 20 degrees C for 8 days, then stored in MELFI at +2 degrees C and -95 degrees C, then recovered at +5 degrees C and at -20 degrees C. One control egg case are kept at 2 degrees C without incubation. After recovery, eggs are germinated and analyzed for radiation effects with mutation assay, genetic assay and biochemical assays.
Information PendingEarth Applications
Radiation effects are critical for biological creatures. The data collected during this investigation may lead a greater understanding of how the radiation defense system is affected by different factors from space radiation and microgravity environment. This data could potentially be used to help develop new treatments and preventative measures for radiation effects.
Information PendingOperational Protocols
Yang Y, Tang L, Tong L, Liu H.Silkworms culture as a source of protein for humans in space. Advances in Space Research. 2009 Apr; 43(8): 1236-1242.
Furusawa T, Nojima K, Ichida M, Nagaoka S, Sugimura Y, Suzuki E, Sumida M, Suzuki H, Simazu T, Omori K, Ishioka N, Fujii H, Nagaoka S. Introduction to the proposed space experiments aboard the ISS using the silkworm, Bombyx mori. Biological Sciences in Space. 2009; 23(2): 61-69. DOI: 10.2187/bss.23.61.
Furusawa T, Fukamoto K, Sakashita T, Suzuki E, Kakizaki T, Hamada N, Funayama T, Suzuki H, Ishioka N, Wada S, Kobayashi Y, Nagaoka S. Targeted heavy-ion microbeam irradiation of the embryo but not yolk in the diapause-terminated egg of the silkworm, Bombyx mori, induces the somatic mutation. Journal of Radiation Research. 2009; 50(4): 371-375. DOI: 10.1269/jrr.09021.
Ground Based Results Publications
Bombyx mori, silkworms to be used in the RadSilk investigation.
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ISS021E028099 - Expedition 21 Commander (CDR) Frank De Winne works on the RadSilk (Integrated Assessment of Long-term Cosmic Radiation Through Biological Responses of the Silkworm, Bombyx mori, in Space) experiment in the JEM (Japanese Experiment Module)
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