Influencing Factors of Space Flight on Expression of Strains of Interleukin-1 (ARIL-1) - 06.24.15

Overview | Description | Applications | Operations | Results | Publications | Imagery

ISS Science for Everyone

Science Objectives for Everyone
Aryl (Aril) will develop methods for controlled changing of the properties of recombinant producer strains of interleukins 1alpha, 1beta and aryl through exposure of germ cultures to orbital flight environments with subsequent selection in laboratory conditions.
Science Results for Everyone
Information Pending

The following content was provided by L. N. Petrov, G. Y. Scherbakov, M.D., Ye N. Sventitski, and is maintained in a database by the ISS Program Science Office.
Experiment Details


Principal Investigator(s)
L. N. Petrov, Biopreparat, Russia
G. Y. Scherbakov, M.D., Biopreparat, Russia
Ye N. Sventitski, Russia

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Sponsoring Space Agency
Russian Federal Space Agency (Roscosmos)

Sponsoring Organization
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Research Benefits
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ISS Expedition Duration
October 2007 - September 2010

Expeditions Assigned

Previous ISS Missions
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Experiment Description

Research Overview
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The experiment consists in determining the effects on the culture samples of the microgravity environment, movement in the geomagnetic field and exposure to space radiation. As a result, it is planned to find the optimal exposure conditions for recombinant microorganism cultures, which will assure the maximum copying ability of plasmids controlling the synthesis of interleukines and aryl, as well as develop methods for controlled changes in the properties of recombinant producer strains of interleukins 1alpha, 1beta, aryl.

To optimize exposure conditions for germ cultures of recombinant producer strains of interleukins 1alpha, 1beta and aryl to space flight environments. Obtaining recombinant strains of producers of bioactive substances with improved properties.

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Space Applications
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Earth Applications
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Operational Requirements
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Operational Protocols
Returned to Earth are Bioekologia cases and photographic materials taken during the experiment

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Results/More Information

The obtained material will be used for ground section of the producer strains with improved properties (increased yield and segregation stability).

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Related Websites
Energia - Science Research on the ISS Russian Segment

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