Influencing Factors of Space Flight on Expression of Strains of Interleukin-1 (ARIL-1) - 10.21.14

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ISS Science for Everyone

Science Objectives for Everyone
Aryl (Aril) will develop methods for controlled changing of the properties of recombinant producer strains of interleukins 1alpha, 1beta and aryl through exposure of germ cultures to orbital flight environments with subsequent selection in laboratory conditions.

Science Results for Everyone
Information Pending

The following content was provided by L. N. Petrov, Ye N. Sventitski, G. Y. Scherbakov, M.D., and is maintained in a database by the ISS Program Science Office.

Experiment Details


Principal Investigator(s)

  • L. N. Petrov, Biopreparat, Russia
  • Ye N. Sventitski, Russia
  • G. Y. Scherbakov, M.D., Biopreparat, Russia

  • Co-Investigator(s)/Collaborator(s)
    Information Pending
    Information Pending
    Sponsoring Space Agency
    Russian Federal Space Agency (Roscosmos)

    Sponsoring Organization
    Information Pending

    Research Benefits
    Information Pending

    ISS Expedition Duration
    October 2007 - September 2010

    Expeditions Assigned

    Previous ISS Missions
    Information Pending

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    Experiment Description

    Research Overview
    Information Pending

    The experiment consists in determining the effects on the culture samples of the microgravity environment, movement in the geomagnetic field and exposure to space radiation. As a result, it is planned to find the optimal exposure conditions for recombinant microorganism cultures, which will assure the maximum copying ability of plasmids controlling the synthesis of interleukines and aryl, as well as develop methods for controlled changes in the properties of recombinant producer strains of interleukins 1alpha, 1beta, aryl.

    To optimize exposure conditions for germ cultures of recombinant producer strains of interleukins 1alpha, 1beta and aryl to space flight environments. Obtaining recombinant strains of producers of bioactive substances with improved properties.

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    Space Applications
    Information Pending

    Earth Applications
    Information Pending

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    Operational Requirements
    Information Pending

    Operational Protocols
    Returned to Earth are Bioekologia cases and photographic materials taken during the experiment

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    Results/More Information
    The obtained material will be used for ground section of the producer strains with improved properties (increased yield and segregation stability).

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    Related Websites
    Energia - Science Research on the ISS Russian Segment

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