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Influencing Factors of Space Flight on Expression of Strains of Interleukin (Aryl)
04.26.13

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Overview | Description | Applications | Operations | Results | Publications | Imagery

Experiment Overview

This content was provided by Ye N. Sventitski, and is maintained in a database by the ISS Program Science Office.

Brief Summary

Aryl (Aril) will develop methods for controlled changing of the properties of recombinant producer strains of interleukins 1alpha, 1beta and aryl through exposure of germ cultures to orbital flight environments with subsequent selection in laboratory conditions.

Principal Investigator(s)

  • Ye N. Sventitski, Russia

    • Co-Investigator(s)/Collaborator(s)

    Information Pending

    Developer(s)
    Information Pending

    Sponsoring Space Agency

    Russian Federal Space Agency (Roscosmos)

    Sponsoring Organization

    Information Pending

    Research Benefits

    Information Pending

    ISS Expedition Duration:

    October 2007 - September 2010

    Expeditions Assigned

    16,18,19/20,21/22,23/24

    Previous ISS Missions

    Information Pending

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    Experiment Description

    Research Overview

    Information Pending

    Description

    The experiment consists in determining the effects on the culture samples of the microgravity environment, movement in the geomagnetic field and exposure to space radiation. As a result, it is planned to find the optimal exposure conditions for recombinant microorganism cultures, which will assure the maximum copying ability of plasmids controlling the synthesis of interleukines and aryl, as well as develop methods for controlled changes in the properties of recombinant producer strains of interleukins 1alpha, 1beta, aryl.

    To optimize exposure conditions for germ cultures of recombinant producer strains of interleukins 1alpha, 1beta and aryl to space flight environments. Obtaining recombinant strains of producers of bioactive substances with improved properties.

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    Applications

    Space Applications

    Information Pending

    Earth Applications

    Information Pending

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    Operations

    Operational Requirements

    Information Pending

    Operational Protocols

    Returned to Earth are Bioekologia cases and photographic materials taken during the experiment

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    Results/More Information

    The obtained material will be used for ground section of the producer strains with improved properties (increased yield and segregation stability).

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    Related Websites
  • Coordinating Scientific and Technical Council of the Russian Space Agency [Russian]
  • Energia - Science Research on the ISS Russian Segment

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    Imagery

    Information provided by the investigation team to the ISS Program Scientist's Office.
    If updates are needed to the summary please contact JSC-ISS-Program-Science-Group. For other general questions regarding space station research and technology, please feel free to call our help line at 281-244-6187 or e-mail at JSC-ISS-Research-Helpline.
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