Study of Embryonic and Stem Cell Development in Microgravity (ESCD) - 08.05.15

Overview | Description | Applications | Operations | Results | Publications | Imagery

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The following content was provided by A. V. Markov, and is maintained in a database by the ISS Program Science Office.
Experiment Details

OpNom:

Principal Investigator(s)
A. V. Markov, S.P. Korolev RSC Energia, Russia

Co-Investigator(s)/Collaborator(s)
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Developer(s)
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Sponsoring Space Agency
Russian Federal Space Agency (Roscosmos)

Sponsoring Organization
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Research Benefits
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ISS Expedition Duration
December 2001 - June 2002

Expeditions Assigned
4

Previous ISS Missions
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Experiment Description

Research Overview
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Description
A study of embryonic and stem cell development in zero-gravity environment.

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Applications

Space Applications
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Earth Applications
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Operations

Operational Requirements
BioTherm incubator with a biological materials insert for actively thermostatting the biological materials at a temperature of 38.5 degrees , Glovebox for accommodating inside it the incubator and an accessories box for the duration of the experiment in space flight environment, Thermal insulation container CPCF-2, to provide a thermally controlled storage environment for the biological materials insert during its transportation from orbit, syringes, needles, waste container, adapter with power cord, battery.

Operational Protocols
Growing cultures of mammalian embryos (mice and sheep), stem cells (undifferentiated), and body (tissue) cells in the incubator in zero gravity. Comparing cells that were experimentally grown in zero gravity with those grown in an incubator on the ground and in test animals.

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Results/More Information

An evaluation of space flight factors impact on the viability and development of embryonic and stem cells outside an animal's body (in vitro) in order to obtain an in-depth knowledge of how these cells develop inside an animal's body (in vivo) and the level of effects produced by gravity.

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Related Websites
Energia - Science Research on the ISS Russian Segment

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Imagery

image BioTherm Incubator.
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image Biotherm in its glovebox.
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