Study of Embryonic and Stem Cell Development in Microgravity (ESCD) - 01.09.14

Overview | Description | Applications | Operations | Results | Publications | Imagery

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This content was provided by A. V. Markov, and is maintained in a database by the ISS Program Science Office.

Experiment Details


Principal Investigator(s)

  • A. V. Markov, S.P. Korolev RSC Energia, Russia
  • Co-Investigator(s)/Collaborator(s)
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    Sponsoring Space Agency
    Russian Federal Space Agency (Roscosmos)

    Sponsoring Organization
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    Research Benefits
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    ISS Expedition Duration
    December 2001 - June 2002

    Expeditions Assigned

    Previous ISS Missions
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    Experiment Description

    Research Overview
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    A study of embryonic and stem cell development in zero-gravity environment.

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    Space Applications
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    Earth Applications
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    Operational Requirements
    BioTherm incubator with a biological materials insert for actively thermostatting the biological materials at a temperature of 38.5 degrees , Glovebox for accommodating inside it the incubator and an accessories box for the duration of the experiment in space flight environment, Thermal insulation container CPCF-2, to provide a thermally controlled storage environment for the biological materials insert during its transportation from orbit, syringes, needles, waste container, adapter with power cord, battery.

    Operational Protocols
    Growing cultures of mammalian embryos (mice and sheep), stem cells (undifferentiated), and body (tissue) cells in the incubator in zero gravity. Comparing cells that were experimentally grown in zero gravity with those grown in an incubator on the ground and in test animals.

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    Results/More Information
    An evaluation of space flight factors impact on the viability and development of embryonic and stem cells outside an animal's body (in vitro) in order to obtain an in-depth knowledge of how these cells develop inside an animal's body (in vivo) and the level of effects produced by gravity.

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    Related Websites

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    image BioTherm Incubator.
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    image Biotherm in its glovebox.
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