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Extraction and Investigation of surface glycoproteins E1-E2 Alphavirises on Earth and in Space (Glidoproteid)
04.26.13

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Overview | Description | Applications | Operations | Results | Publications | Imagery

Experiment Overview

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Brief Summary

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Principal Investigator(s)

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Co-Investigator(s)/Collaborator(s)

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Developer(s)
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Sponsoring Space Agency

Russian Federal Space Agency (Roscosmos)

Sponsoring Organization

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Research Benefits

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ISS Expedition Duration:

August 2001 - April 2009

Expeditions Assigned

3,13,14,15,16,18

Previous ISS Missions

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Experiment Description

Research Overview

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Description

Acquisition of data on an atomic structure of biomolecules of glycoproteins E1-E2 of the maximum high resolution to produce effective and safe vaccines of a new generation and develop new antiviral preparations and diagnostic systems.

Test of the crystallization process, production of crystals of glycoproteins E1-E2 analogs of alpha viruses in microgravity conditions to make the subseauent ground roentgenodiffraction analysis.

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Applications

Space Applications

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Earth Applications

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Operations

Operational Requirements

Kriogem-03M Refrigerator to maintain proper temperature while onboard, Reusable Heat-insulated container with cold accumulator TVK-M, Maintain proper temperature while returning the crystals to the Earth, CPCF Module to grow the protein crystals in orbit and deliver to Earth, Activation Device to activate crystal growth process.

Operational Protocols

Obtain crystals of alpha-virus E1-E2 glicoproteins analogs.

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Results/More Information

Universal biocrystallization cassettes and experiment footage returned to the Earth.

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Related Websites
  • Coordinating Scientific and Technical Council of the Russian Space Agency [Russian]
  • Energia - Science Research on the ISS Russian Segment

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    Imagery

    image Kriogem-03M Refridgerator maintains proper temperature onboard. Reusable heat-insulated container with cold accumulator TVK-M maintains proper temperature while returning the crystals to the Earth. CPCF Module grows the protein crystals in the orbit and delivery to the Earth. Activation Device activates crystal growth process.
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    Information provided by the investigation team to the ISS Program Scientist's Office.
    If updates are needed to the summary please contact JSC-ISS-Program-Science-Group. For other general questions regarding space station research and technology, please feel free to call our help line at 281-244-6187 or e-mail at JSC-ISS-Research-Helpline.
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