Extraction and Investigation of surface glycoproteins E1-E2 Alphavirises on Earth and in Space (Glykoproteid-K) - 01.09.14

Overview | Description | Applications | Operations | Results | Publications | Imagery

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This content was provided by G. Y. Scherbakov, M.D., K. A. Miroshnikov, and is maintained in a database by the ISS Program Science Office.

Experiment Details

OpNom:

Principal Investigator(s)

  • G. Y. Scherbakov, M.D., Biopreparat, Russia
  • K. A. Miroshnikov, Shubnikiv Institut of Crystallograhy of Russian Academy of Sciences (IC RAS), Russia
  • Co-Investigator(s)/Collaborator(s)
    Information Pending

    Developer(s)
    Information Pending

    Sponsoring Space Agency
    Russian Federal Space Agency (Roscosmos)

    Sponsoring Organization
    Information Pending

    Research Benefits
    Information Pending

    ISS Expedition Duration:
    April 2005 - October 2008

    Expeditions Assigned
    11,13,16,17

    Previous ISS Missions
    Information Pending

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    Experiment Description

    Research Overview
    Information Pending

    Description
    Acquisition of data on an atomic structure of biomolecules of glycoproteins E1-E2 of the maximum high resolution to produce effective and safe vaccines of a new generation and develop new antiviral preparations and diagnostic systems.

    Test of the crystallization process, production of crystals of glycoproteins E1-E2 analogs of alpha viruses in microgravity conditions to make the subseauent ground roentgenodiffraction analysis.

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    Applications

    Space Applications
    Information Pending

    Earth Applications
    Information Pending

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    Operations

    Operational Requirements
    Kriogem-03M Refrigerator to maintain proper temperature while onboard, Reusable Heat-insulated container with cold accumulator TVK-M, Maintain proper temperature while returning the crystals to the Earth, CPCF Module to grow the protein crystals in orbit and deliver to Earth, Activation Device to activate crystal growth process.

    Operational Protocols
    Obtain crystals of alpha-virus E1-E2 glicoproteins analogs.

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    Results/More Information
    Universal biocrystallization cassettes and experiment footage returned to the Earth.

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    Related Websites

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    Imagery

    image Kriogem-03M Refridgerator maintains proper temperature onboard. Reusable heat-insulated container with cold accumulator TVK-M maintains proper temperature while returning the crystals to the Earth. CPCF Module grows the protein crystals in the orbit and delivery to the Earth. Activation Device activates crystal growth process.
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