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Morphofunctional Characteristic of Blood Cells and the Intensity of Erythropoiesis in Humans by the Influence of Factors of Space Flight (Gematologia)
04.26.13

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Overview | Description | Applications | Operations | Results | Publications | Imagery

Experiment Overview

This content was provided by S M. Ivanova, and is maintained in a database by the ISS Program Science Office.

Brief Summary

Information Pending

Principal Investigator(s)

  • S M. Ivanova, Russia

    • Co-Investigator(s)/Collaborator(s)

    Information Pending

    Developer(s)
    Information Pending

    Sponsoring Space Agency

    Russian Federal Space Agency (Roscosmos)

    Sponsoring Organization

    Information Pending

    Research Benefits

    Information Pending

    ISS Expedition Duration:

    April 2003 - April 2006

    Expeditions Assigned

    7,8,9,10,11,12

    Previous ISS Missions

    Information Pending

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    Experiment Description

    Research Overview

    Information Pending

    Description

    Deriving new data on the space flight factors impact on the human blood system to extend diagnostic and prognostic capabilities of detecting mechanisms of arising shifts in hematologic indices ("space anemia", lymphocytosis).

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    Applications

    Space Applications

    Information Pending

    Earth Applications

    Information Pending

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    Operations

    Operational Requirements

    Samples of venous blood in KV-03 container; Eritrotsit' kit with fingertip blood samples; Data on hemoglobin content transmitted via radio links; The logbook sheets with crew members' records.

    Operational Protocols

    Collecting samples of venous and capillary blood with the aim: to study erythrocyte forms; to investigate metabolism of erythrocytes, cell membrane conditions, indices of ferrum metabolism and erythropoetin content in blood.

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    Results/More Information

    The findings will allow to detect mechanisms of the blood system adaptation to space flight factors, to extend the system of diagnostic and prognostic criteria for assessment of human physical state under extreme effects, as well as they can be used to develop prophylactic and pharmacologic preparations to treat disturbances in the blood system in these conditions.

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    Results Publications

      Ivanova SM, Brazhe NA, Luneva OG, Yarlikova YV, Labetskaya OI, Parshina EY, Baizhumanov AA, Maksimov GV, Morukov BV.  Physical-chemical Properties of Plasma Membrane and Function of Erythrocytes of Cosmonauts After Long-term Space Flight. Acta Astronautica. 2011; 68: 1517-1522. DOI: 10.1016/j.actaastro.2010.06.046.
      Grigoriev AI, Ivanova SM, Morukov BV, Maksimov GV.  Development of Cell Hypoxia Induced by Factors of Long-term Spaceflight. Doklady Biochemistry and Biophysics. 2008; 422: 308-311. DOI: 10.1134/S1607672908050141. PMID: 19024564.

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    Ground Based Results Publications

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    ISS Patents

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    Related Publications

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    Related Websites
  • Coordinating Scientific and Technical Council of the Russian Space Agency [Russian]
  • Energia - Science Research on the ISS Russian Segment

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    Imagery

    image Plasma-03 centrifuge for blood separation into serum and plasma. Image courtesy of Russian Space Agency (Energia Website).
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    Information provided by the investigation team to the ISS Program Scientist's Office.
    If updates are needed to the summary please contact JSC-ISS-Program-Science-Group. For other general questions regarding space station research and technology, please feel free to call our help line at 281-244-6187 or e-mail at JSC-ISS-Research-Helpline.
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