Vegatative (Autonomic) Regulation of the Cardio-Respiratory System of Humans in Conditions of Weightlessness (Puls (Pulse)) - 10.21.14

Overview | Description | Applications | Operations | Results | Publications | Imagery
ISS Science for Everyone

Science Objectives for Everyone
MBI-9 (Pulse) is a cardiological assessment which collects data on arterial blood pressure and an electrocardiogram is performed to better understand the effects of weightlessness on the human cardiorespiratory system.

Science Results for Everyone
Information Pending



The following content was provided by Roman M. Baevsky, M.D., and is maintained in a database by the ISS Program Science Office.

Experiment Details

OpNom

Principal Investigator(s)

  • Roman M. Baevsky, M.D., Institute of Medical and Biological Problems of Russian Academy of Sciences (IMBP RAS), Moscow, Russia

  • Co-Investigator(s)/Collaborator(s)
    Information Pending
    Developer(s)
    Information Pending
    Sponsoring Space Agency
    Russian Federal Space Agency (Roscosmos)

    Sponsoring Organization
    Information Pending

    Research Benefits
    Information Pending

    ISS Expedition Duration
    June 2002 - September 2006

    Expeditions Assigned
    5,6,7,8,9,10,11,12,13

    Previous ISS Missions
    Information Pending

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    Experiment Description

    Research Overview
    Information Pending

    Description
    Acquisition of new scientific information to extend ideas about mechanisms of cardio-respiratory system adaptation to long-duration space flights.

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    Applications

    Space Applications
    Information Pending

    Earth Applications
    Information Pending

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    Operations

    Operational Requirements
    Pulse Kit, Laptop, Pulse Pouch.

    Operational Protocols
    Study of impact of long-duration space flight factors on the functional state of cardiovascular and respiratory systems of cosmonauts by using computer modifications of electrocardiography, sphygmography and pneumotachography. Study of control processes for the cardiorespiratory system. Control of cardioresparatory homeostasis indices (average pulse rate, cardiac output and stroke volume, phase structure of the cardiac cycle, systole efficiency, average respiration rate, volumetric and rate characteristics of the expired air). Control of indices of the control system of the cardiorespiratory system.

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    Results/More Information
    Improvement of the cosmonauts' medical supervision system in a long-duration flight. Development of new criteria for prognostic assessment of probable violations of cardiorespiratory homeostasis.

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    Results Publications

      Baevsky RM, Baranov VM, Funtova II, Diedrich A, Pashenko AV, Chernikova AG, Drescher J, Jordan J, Tank J.  Autonomic cardiovascular and respiratory control during prolonged spaceflights aboard the International Space Station. Journal of Applied Physiology. 2007 July; 103(1): 156-161. DOI: 10.1152/japplphysiol.00137.2007.

      Baevsky RM, Pashchenko AV, Funtova II, Chernikova AG.  Study of Vegetative Regulation of the Cardiovascular System in Long-Term Spaceflights on the International Space Station. Computerized Medicine Applied Science Conference. Kharkov, Ukraine; 2005 Jun 23-25

      Baranov VM, Baevsky RM, Pashchenko AV, Funtova II, Chernikova AG, Drescher J, Tank J.  Autonomous regulation of cardiovascular system in cosmonauts and prospects of researches on ISS. 57th International Astronautical Congress, Valencia, Spain; 2006 Oct 2-6

      Baevsky RM, Funtova II.  Analysis of Cardiac Rhythm Variability in Experiments on Board the International Space Station. All-Russian Symposium on the Variability of Cardiac Rhythm: Theoretical Aspects and Practical Application, Izhevsk, Russia; 2003 Nov

      Baevsky RM, Chernikova AG.  Heart rate variability analysis in evaluation of functional state in humans during long-term space flight. 14th Man in Space Symposium. Banff, Alberta, Canada; 2003 May

      Baevsky RM, Baranov VM, Bogomolov VV.  Prospects of  development of the medical control automated systems at the ISS on the basis of onboard equipment “Puls”and “Pneumocard” using. 54th International Astronautical Congress, Bremen, Germany; 2003 September 29 - October 3

      Baranov VM, Baevsky RM, Drescher J, Tank J.  Investigations of the cardiovascular and respiratory systems on board the international space station: experiments PULS and PNEUMOCARD. 53rd International Astronautical Congress, The World Space Congress, Houston, TX; 2002 October 10-19

      Chernikova AG, Baevsky RM, Nikulina GA, Funtova II.  Analysis of Cardiac Rhythm Variability in Assessing Human Functional Status During Spaceflight. 19th Congress of the I.P. Pavlov Physiological Society; 2004

      Chernikova AG, Baevsky RM.  Mathematical Models of Functional Status Based on Analysis of Cardiac Rhythm Variability. All-Russian Symposium on the Variability of Cardiac Rhythm: Theoretical Aspects and Practical Application, Izhevsk, Russia; 2004 Sep

      Baevsky RM, Funtova II, Chernikova AG.  Principles of Creating a Medical Expert System for Evaluating Prenosological Statuses in Long-Term Spaceflights. Computerized Medicine Applied Science Conference. Kharkov, Ukraine; 2007 Sep 14-15

      Tank J, Baevsky RM, Drescher J, Funtova II.  Impact of cardiovascular research on board the International Space Station on the design of new medical devices. 2nd European Medical and Biological Engineering Conference (EMBEC). Vienna, Austria.; 2002 Dec 4-8

      Chernikova AG.  Mathematical Modeling of the Space of Functional Statuses Using Data from the Analysis of Cardiac Rhythm Variability. The Body and Environment: Adaptation to Extreme Conditions. Moscow, Russia; 2003 374-376.

      Tank J, Chernikova AG, Baevsky RM.  Types of regulation and adaptation reactions in space flights. 5th Symposium of Autonomic Regulation, Lisbon, Portugal ; 2006 May 25-29

      Pashchenko AV, Baevsky RM.  New method for orthostatic test evaluation based on heart rate variability. Proceedings of the European Study Group on Cardiovascular Oscillations. Jena, Germany; 2006 May 15-17 78-81.

      Baevsky RM, Okhritsky AA, Pashchenko AV, Prilutsky DA, Funtova II.  Medical polygraph software for scientific research. Meditsinskaia Tekhnika (Biomedical Engineering). 2007; 1: 19-24.

      Baevsky RM.  Theoretical and Applied Aspects of Controlling Adaptive Processes in Long-Term Spaceflight Conditions. The Body and Environment: Adaptation to Extreme Conditions. Moscow, Russia; 2003 24-26.

      Baevsky RM, Baranov VM, Chernikova AG, Funtova II, Pashchenko AV, Tank J.  Heart rate variability as indicator of cardioregulatory system. Experiment result of ISS. Proceedings of the European Study Group on Cardiovascular Oscillations. Jena, Germany; 2006 May 15-17 74-77.

      Baevsky RM, Luchitskaya ES, Funtova II, Chernikova AG.  Study of the autonomic regulation of blood circulation during a long-term space flight. Human Physiology. 2013 October 11; 39(5): 486-495. DOI: 10.1134/S0362119713050046.

      Baevsky RM, Chernikova AG, Funtova II.  Assessment of Functional Status and Type of Regulation of the Circulatory System in Spaceflight Conditions Using Data for the Analysis of Cardiac Rhythm Variability. 7th Applied Science Conference on Diagnosis and Treatment of Disruptions to the Regulation of the Cardiovascular System. Moscow, Russia; 2005 Mar 23 310-318.

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    Ground Based Results Publications

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    ISS Patents

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    Related Publications

      Baevsky RM.  A System for Evaluating and Predicting the State of Health of Cosmonauts, and Prospects for its Development. Aviakosmicheskaia i Ekologicheskaia Meditsina (Aerospace and Environmental Medicine). 2001; 2: 36-45.

      Baevsky RM, Bersenev YY, Drescher J.  Computer Systems for Studying Circulation and Respiration on Board the International Space Station. Materials of the 12th Conference on Space Biology and Aerospace Medicine; 2002 38-39.

      Baevsky RM, Nikulina GA, Funtova II, Chernikova AG.  Vegetative Regulation of Circulation. Orbital Station Mir. 2000; 2: 36-68.

      Baevsky RM, Chernikova AG.  On the Problem of Physiological Norms: a Mathematical Model of Functional Status Based on Analysis of Variability of cardiac Rhythm. Aviakosmicheskaia i Ekologicheskaia Meditsina (Aerospace and Environmental Medicine). 2002; 5: 34-37.

      Tank J, Baevsky RM, Berseneva AP.  –†rospects for development of novel research apparatuses for the international Space Station based on the experience of clinical and physiological investigations of the circulation regulating mechanisms. Symposium on the Achievements of Space Medicine in the Practice of Health Care and Industry. Berlin, Germany; 2001 164-176.

      Baevsky RM.  Predicting Conditions on the Line Between the Norm and Pathology. Meditsina. 1979: 225.

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    Related Websites
    Energia - Science Research on the ISS Russian Segment

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    Imagery

    image The Pulse Kit.
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