Crystalization of th Protein Caf1M and its Combination with the Terminal Peptide Caf1 as the Elements for the Development of a New Generation of Antimicrobial Medicinal Preparations and Components of Vaccines from Yeasts (Kaf) - 08.05.15

Overview | Description | Applications | Operations | Results | Publications | Imagery

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The following content was provided by G. Y. Scherbakov, M.D., G. Ya. Tscherbakov, and is maintained in a database by the ISS Program Science Office.
Experiment Details

OpNom:

Principal Investigator(s)
G. Y. Scherbakov, M.D., Biopreparat, Russia
G. Ya. Tscherbakov, Biopreparat, Russia

Co-Investigator(s)/Collaborator(s)
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Developer(s)
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Sponsoring Space Agency
Russian Federal Space Agency (Roscosmos)

Sponsoring Organization
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Research Benefits
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ISS Expedition Duration
April 2006 - October 2008

Expeditions Assigned
13,16,17

Previous ISS Missions
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Experiment Description

Research Overview
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Description
Carrying out crystallization with gene-engineering molecular complexes Caf 1M and Caf 1 with synthetic peptide under zero-gravity conditions.

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Applications

Space Applications
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Earth Applications
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Operations

Operational Requirements
Luch-2 equipment accommodating multipurpose crystallization cassettes, Thermal insulating container Biokont-T for transportation of the Luch-2 equipment, Temperature-stable container "AQUA 01".

Operational Protocols
Development tests of best crystallization conditions and production of crystals of proteins Caf1 and complex Caf1M with synthetic peptide Caf1 under flight conditions.

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Results/More Information

The experimental investigation will enable to develop biologically active substances (cytokinins and protective antigens) for medicine and veterinary medicine.

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Related Websites
Energia - Science Research on the ISS Russian Segment

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Imagery

image Luch-2 equipment accommodating multipurpose crystallization cassettes.
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image Thermal insulating container Biokont-T for transportation of the Luch-2 equipment.
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image Temperature-stable container "AQUA 01".
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