Development of Methods for Designing New Recombinants Producing Strains of Bacteria in Space Flight (Konyugatsia-EFR) - 12.03.13
Science Objectives for Everyone
Kon'yugatsiya (Conjugation) studies the exchange of genetic material in microgravity in order to develop strains that can produce new target proteins.
Science Results for Everyone
Russian Federal Space Agency (Roscosmos)Sponsoring Organization
Information PendingResearch Benefits
Information PendingISS Expedition Duration:
April 2003 - October 2008Expeditions Assigned
7,9,10,12,13,14,15,16,17Previous ISS Missions
Development of the methods for designing new recombinant producing strains which are essential for protein medicine by means of the bacterial conjugation and plasmid mobilization technique during space flight.
Information PendingEarth Applications
Thermal insulating container Biokont-T, Recomb-K equipment, Thermostatically controlled container 'Akvarius', Cryogem-03 refrigerator.Operational Protocols
Study the conjugations of different proteins in the microgravity environment.
As follows from the experimental results, it is planned to select optimal conditions for genetic material transfer during bacterial conjugation and protoplast fusion under orbital flight conditions with a maximum output of new recombinant producing strains, which are essential for protein medicine. The developed procedure will be used to create new producing strains of biologically active substances intended for manufacturing medicines.
Thermal insulating container 'Biokont-T', Recomb-K equipment, thermostatically controlled container 'Akvarius'.
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