Development of Methods for Designing New Recombinants Producing Strains of Bacteria in Space Flight (Konyugatsia-EFR) - 07.14.16
Kon'yugatsiya (Conjugation) studies the exchange of genetic material in microgravity in order to develop strains that can produce new target proteins. Science Results for Everyone
Information Pending Experiment Details
Yu. P. Zerov, Biopreparat, Russia
Sponsoring Space Agency
Russian Federal Space Agency (Roscosmos)
ISS Expedition Duration
April 2003 - October 2003; April 2004 - April 2005; October 2005 - October 2008
Development of the methods for designing new recombinant producing strains which are essential for protein medicine by means of the bacterial conjugation and plasmid mobilization technique during space flight.
Operational Requirements and Protocols
Thermal insulating container Biokont-T, Recomb-K equipment, Thermostatically controlled container 'Akvarius', Cryogem-03 refrigerator.
Study the conjugations of different proteins in the microgravity environment.
Decadal Survey Recommendations
Information Pending^ back to top
As follows from the experimental results, it is planned to select optimal conditions for genetic material transfer during bacterial conjugation and protoplast fusion under orbital flight conditions with a maximum output of new recombinant producing strains, which are essential for protein medicine. The developed procedure will be used to create new producing strains of biologically active substances intended for manufacturing medicines.^ back to top
Energia - Science Research on the ISS Russian Segment
Thermal insulating container 'Biokont-T', Recomb-K equipment, thermostatically controlled container 'Akvarius'.
+ View Larger Image