Development of Methods for Designing New Recombinants Producing Strains of Bacteria in Space Flight (Konyugatsia-EFR) - 08.20.14

Overview | Description | Applications | Operations | Results | Publications | Imagery
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Science Objectives for Everyone
Kon'yugatsiya (Conjugation) studies the exchange of genetic material in microgravity in order to develop strains that can produce new target proteins.

Science Results for Everyone
Information Pending



The following content was provided by Yu. P. Zerov, and is maintained in a database by the ISS Program Science Office.

Experiment Details

OpNom

Principal Investigator(s)

  • Yu. P. Zerov, Biopreparat, Russia

  • Co-Investigator(s)/Collaborator(s)
    Information Pending
    Developer(s)
    Information Pending
    Sponsoring Space Agency
    Russian Federal Space Agency (Roscosmos)

    Sponsoring Organization
    Information Pending

    Research Benefits
    Information Pending

    ISS Expedition Duration
    April 2003 - October 2008

    Expeditions Assigned
    7,9,10,12,13,14,15,16,17

    Previous ISS Missions
    Information Pending

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    Experiment Description

    Research Overview
    Information Pending

    Description
    Development of the methods for designing new recombinant producing strains which are essential for protein medicine by means of the bacterial conjugation and plasmid mobilization technique during space flight.

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    Applications

    Space Applications
    Information Pending

    Earth Applications
    Information Pending

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    Operations

    Operational Requirements
    Thermal insulating container Biokont-T, Recomb-K equipment, Thermostatically controlled container 'Akvarius', Cryogem-03 refrigerator.

    Operational Protocols
    Study the conjugations of different proteins in the microgravity environment.

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    Results/More Information
    As follows from the experimental results, it is planned to select optimal conditions for genetic material transfer during bacterial conjugation and protoplast fusion under orbital flight conditions with a maximum output of new recombinant producing strains, which are essential for protein medicine. The developed procedure will be used to create new producing strains of biologically active substances intended for manufacturing medicines.

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    Related Websites
    Energia - Science Research on the ISS Russian Segment

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    Imagery

    image Thermal insulating container 'Biokont-T', Recomb-K equipment, thermostatically controlled container 'Akvarius'.
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