Fact Sheet

Text Size

Development of Methods for Designing New Recombinants Producing Strains of Bacteria in Space Flight (Conjugation)
04.26.13

OpNom:

Overview | Description | Applications | Operations | Results | Publications | Imagery

Experiment Overview

This content was provided by Y. N. Sventitsky, and is maintained in a database by the ISS Program Science Office.

Brief Summary

Kon'yugatsiya (Conjugation) studies the exchange of genetic material in microgravity in order to develop strains that can produce new target proteins.

Principal Investigator(s)

  • Y. N. Sventitsky, Russia

    • Co-Investigator(s)/Collaborator(s)

    Information Pending

    Developer(s)
    Information Pending

    Sponsoring Space Agency

    Russian Federal Space Agency (Roscosmos)

    Sponsoring Organization

    Information Pending

    Research Benefits

    Information Pending

    ISS Expedition Duration:

    April 2003 - March 2010

    Expeditions Assigned

    7,9,10,12,13,14,15,16,17,18,19/20,21/22

    Previous ISS Missions

    Information Pending

    ^ back to top


    Experiment Description

    Research Overview

    Information Pending

    Description

    Development of the methods for designing new recombinant producing strains which are essential for protein medicine by means of the bacterial conjugation and plasmid mobilization technique during space flight.

    ^ back to top


    Applications

    Space Applications

    Information Pending

    Earth Applications

    Information Pending

    ^ back to top


    Operations

    Operational Requirements

    Thermal insulating container Biokont-T, Recomb-K equipment, Thermostatically controlled container 'Akvarius', Cryogem-03 refrigerator.

    Operational Protocols

    Study the conjugations of different proteins in the microgravity environment.

    ^ back to top


    Results/More Information

    As follows from the experimental results, it is planned to select optimal conditions for genetic material transfer during bacterial conjugation and protoplast fusion under orbital flight conditions with a maximum output of new recombinant producing strains, which are essential for protein medicine. The developed procedure will be used to create new producing strains of biologically active substances intended for manufacturing medicines.

    ^ back to top


    Related Websites
  • Energia - Science Research on the ISS Russian Segment

    • ^ back to top


    Imagery

    image Thermal insulating container 'Biokont-T', Recomb-K equipment, thermostatically controlled container 'Akvarius'.
    + View Larger Image


    Information provided by the investigation team to the ISS Program Scientist's Office.
    If updates are needed to the summary please contact JSC-ISS-Program-Science-Group. For other general questions regarding space station research and technology, please feel free to call our help line at 281-244-6187 or e-mail at JSC-ISS-Research-Helpline.
    › Back To Top