Influence of Factors of Space Flight on Superoxide Strain Producer (OChB-1) - 01.09.14

Overview | Description | Applications | Operations | Results | Publications | Imagery

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This content was provided by Yu. P. Zerov, and is maintained in a database by the ISS Program Science Office.

Experiment Details

OpNom:

Principal Investigator(s)

  • Yu. P. Zerov, Biopreparat, Russia
  • Co-Investigator(s)/Collaborator(s)
    Information Pending

    Developer(s)
    Information Pending

    Sponsoring Space Agency
    Russian Federal Space Agency (Roscosmos)

    Sponsoring Organization
    Information Pending

    Research Benefits
    Information Pending

    ISS Expedition Duration:
    October 2007 - October 2009

    Expeditions Assigned
    16,17,18,19/20

    Previous ISS Missions
    Information Pending

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    Experiment Description

    Research Overview
    Information Pending

    Description
    Effect produced by SFFs on strain producing superoxidodismutase (SOD). To develop methods for increasing the yield of recombinant strains producing human Cu-, Zn-superoxide dismutase through incubating the germ culture in space environment with subsequent selection under laboratory conditions.

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    Applications

    Space Applications
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    Earth Applications
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    Operations

    Operational Requirements
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    Operational Protocols
    To optimize exposure conditions for germ cultures of recombinant strains producing superoxide dismutase (SOD) in orbital space flight environment. To develop exposure conditions for the yeast SOD producer strain. To obtain recombinant strains producing bioactive substances with improved properties. Returned to Earth are Bioekologia cases and photographic materials taken during the experiment.

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    Results/More Information
    The obtained material will be used for ground section of the producer strains with improved properties (increased yield and segregation stability). The selected high-yield lines of the yeast SOD producer strain will be used for manufacturing SOD drugs.

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    Related Websites

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    Imagery