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Influence of Factors of Space Flight on Superoxide Strain Producer (OChB)
04.26.13

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Overview | Description | Applications | Operations | Results | Publications | Imagery

Experiment Overview

This content was provided by Ye N. Sventitski, and is maintained in a database by the ISS Program Science Office.

Brief Summary

Information Pending

Principal Investigator(s)

  • Ye N. Sventitski, Russia

    • Co-Investigator(s)/Collaborator(s)

    Information Pending

    Developer(s)
    Information Pending

    Sponsoring Space Agency

    Russian Federal Space Agency (Roscosmos)

    Sponsoring Organization

    Information Pending

    Research Benefits

    Information Pending

    ISS Expedition Duration:

    October 2007 - September 2011

    Expeditions Assigned

    16,17,18,19/20,21/22,23/24,27/28

    Previous ISS Missions

    Information Pending

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    Experiment Description

    Research Overview

    Information Pending

    Description

    Effect produced by SFFs on strain producing superoxidodismutase (SOD). To develop methods for increasing the yield of recombinant strains producing human Cu-, Zn-superoxide dismutase through incubating the germ culture in space environment with subsequent selection under laboratory conditions.

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    Applications

    Space Applications

    Information Pending

    Earth Applications

    Information Pending

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    Operations

    Operational Requirements

    Information Pending

    Operational Protocols

    To optimize exposure conditions for germ cultures of recombinant strains producing superoxide dismutase (SOD) in orbital space flight environment. To develop exposure conditions for the yeast SOD producer strain. To obtain recombinant strains producing bioactive substances with improved properties. Returned to Earth are Bioekologia cases and photographic materials taken during the experiment.

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    Results/More Information

    The obtained material will be used for ground section of the producer strains with improved properties (increased yield and segregation stability). The selected high-yield lines of the yeast SOD producer strain will be used for manufacturing SOD drugs.

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    Related Websites
  • Coordinating Scientific and Technical Council of the Russian Space Agency [Russian]
  • Energia - Science Research on the ISS Russian Segment

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    Imagery

    Information provided by the investigation team to the ISS Program Scientist's Office.
    If updates are needed to the summary please contact JSC-ISS-Program-Science-Group. For other general questions regarding space station research and technology, please feel free to call our help line at 281-244-6187 or e-mail at JSC-ISS-Research-Helpline.
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