Influence of Factors of Space Flight on Superoxide Strain Producer (OChB-1) - 05.13.15

Overview | Description | Applications | Operations | Results | Publications | Imagery

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The following content was provided by Yu. P. Zerov, and is maintained in a database by the ISS Program Science Office.
Experiment Details

OpNom:

Principal Investigator(s)
Yu. P. Zerov, Biopreparat, Russia

Co-Investigator(s)/Collaborator(s)
Information Pending

Developer(s)
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Sponsoring Space Agency
Russian Federal Space Agency (Roscosmos)

Sponsoring Organization
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Research Benefits
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ISS Expedition Duration
October 2007 - October 2009

Expeditions Assigned
16,17,18,19/20

Previous ISS Missions
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Experiment Description

Research Overview
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Description
Effect produced by SFFs on strain producing superoxidodismutase (SOD). To develop methods for increasing the yield of recombinant strains producing human Cu-, Zn-superoxide dismutase through incubating the germ culture in space environment with subsequent selection under laboratory conditions.

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Applications

Space Applications
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Earth Applications
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Operations

Operational Requirements
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Operational Protocols
To optimize exposure conditions for germ cultures of recombinant strains producing superoxide dismutase (SOD) in orbital space flight environment. To develop exposure conditions for the yeast SOD producer strain. To obtain recombinant strains producing bioactive substances with improved properties. Returned to Earth are Bioekologia cases and photographic materials taken during the experiment.

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Results/More Information

The obtained material will be used for ground section of the producer strains with improved properties (increased yield and segregation stability). The selected high-yield lines of the yeast SOD producer strain will be used for manufacturing SOD drugs.

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Related Websites
Energia - Science Research on the ISS Russian Segment

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Imagery