Influence of the Flow of Heavily Charged Particles of Space Radiation on Gentic Properties of Cell Production (Biotrack-A) - 01.09.14

Overview | Description | Applications | Operations | Results | Publications | Imagery

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Biotrack-A focused on the effects of cosmic radiation on recombination among bacterial strains.

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This content was provided by Tatiana K. Krasheninnikova, O. E. Krasheninnikova, and is maintained in a database by the ISS Program Science Office.

Experiment Details

OpNom:

Principal Investigator(s)

  • Tatiana K. Krasheninnikova, Institute for Applied Biochemistry and Machine Building (Biohimmash), Russia
  • O. E. Krasheninnikova, Russia
  • Co-Investigator(s)/Collaborator(s)
    Information Pending

    Developer(s)
    Information Pending

    Sponsoring Space Agency
    Russian Federal Space Agency (Roscosmos)

    Sponsoring Organization
    Information Pending

    Research Benefits
    Information Pending

    ISS Expedition Duration:
    April 2006 - March 2013

    Expeditions Assigned
    13,14,15,16,17,18,19/20,21/22,23/24,25/26,27/28,29/30,31/32,33/34

    Previous ISS Missions
    Information Pending

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    Experiment Description

    Research Overview
    Information Pending

    Description
    Study a correlation between the alteration of genetic properties, productivity of recombinant strains in microgravity, and exposure to heavy charged space particles.

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    Applications

    Space Applications
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    Earth Applications
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    Operations

    Operational Requirements
    Vial with an ampoule with lyophilized cultures, Tube with biosample vials, Temperature data logger, Thermoluminescent detector, Track detector

    Operational Protocols
    Study a long-duration effect of space radiation factors on cultures of recombinant strains producing biologically active substances in spaceflight, as well as their growth characteristics and plasmid segregation stability. Study and test a technique for selecting highly productive strains from the cultures exposed in spaceflight. Record and analyze heavy nuclear tracks and total radiation dose. Determine a correlation between alterations of genetic properties of the subject biological objects with a different level of organization (microorganisms, plant and animal cells) and number of hits of heavy charged space particles.

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    Results/More Information
    Experiment data collected in this experiment will make it possible to look into the action of molecular mechanisms leading to disordering in genetic cell apparatus caused by an increased level of ionizining radiation acting in a spaceflight along with the microgravity and other extreme environment conditions, that will find application in development of orbital space stations of a new generation, as well as during long-duration spaceflights.

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    Imagery