T-Cell Growth System (T-CGS) - 01.09.14
Science Objectives for Everyone
T-Cell Growth System (T-CGS) can propagate live mouse, rat, and human thymus tissue to investigate the problem of reduced white blood cell counts in long-duration crewmembers.
Science Results for Everyone
Paragon Space Development Corporation, Tucson, AZ, United States
Sponsoring Space Agency
National Aeronautics and Space Administration (NASA)
Human Exploration and Operations Mission Directorate (HEOMD)
ISS Expedition Duration
Previous ISS Missions
T-CGS is unique hardware that is being newly utilized for microgravity research.
- The T-Cell Growth System (T-CGS) is designed to maintain cell cultures in a 2-dimensional petri dish by providing nutrients in a controlled fashion and a growth substrate in microgravity.
- The growth nutrients are transferred via a wick to a growth substrate using a novel silica tile material. The units are designed to be maintained at 37 degrees C and to contain a 5% carbon dioxide/air combination environment through the use of non-permeable seals and material.
The T-CGS is designed to allow for research into the physiological effects of microgravity on the development of cells, especially for the development of precursor immune cells.The T-CGS is 7.6 cm x 7.6 cm x 3.8 cm. The assembly weighs 15 kg and requires no power. The crewmember is responsible for placing the T-CGS inside an incubator following arrival at ISS for activation. Once competed the T-CGS will be returned to Earth. Operations
- T-CGS is launched and transferred to the ISS for initiation. T-CGS is placed inside an incubator for a set time designated by the investigator.
- Following completion of the experiment the T-CGS is removed from the incubator and returned to Earth.
Ground Based Results Publications
T-Cell Growth System for use on the Shuttle and ISS. The sealed Petri Dish system propagates live mouse, rat, and human thymus tissue to investigate the problem of reduced white blood cell count in long-duration astronauts. Image courtesy of Paragon Space Development Corporation.
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