Long Term Microgravity: A Model for Investigating Mechanisms of Heart Disease with New Portable Equipment (Card) - 12.03.13
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The Long Term Microgravity: A Model for Investigating Mechanisms of Heart Disease with New Portable Equipment (Card) experiment studies blood pressure decreases in the human body exposed to microgravity on board the ISS.
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Danish Aerospace Medical Centre of Research, Copenhagen, , Denmark
European Space Agency (ESA)Sponsoring Organization
Information PendingResearch Benefits
Information PendingISS Expedition Duration:
September 2006 - September 2012Expeditions Assigned
14,19/20,21/22,25/26,27/28,29/30,31/32Previous ISS Missions
Card is an ongoing USOS integrated investigation which began on ISS Expedition 19/20.
- Blood pressure will be measured automatically using a portable device at various intervals.
- Cardiac output will be measured using the foreign gas rebreathing technique.
- Urine will be collected to measure renal sodium output.
- Blood will be collected to test for the determination of chronic sympathetic nervous activity.
The Long Term Microgravity: A Model for Investigating Mechanisms of Heart Disease with New Portable Equipment (Card) experiment studies blood pressure decreases when the human body is exposed to microgravity. In order to increase the blood pressure to the level it was on Earth, salt is added to the crewmembers' diet. To monitor this, blood pressure readings and urine samples are performed at different intervals during the mission.In microgravity, the cardiovascular system relaxes causing a drop in the blood volume and pressure. This also causes the fluid and sodium retaining systems to be activated. One theory of this occurrence is that the body's of sodium is decreased. This investigation will examine whether blood pressure and volume can be restored to the same levels that were measured during groundbased measurements by adding additional salt to the astronauts' food.
Information PendingEarth Applications
Card requires the collection of urine and blood samples. Blood pressure will be measured by a portable equipment device called an oscillometry. The foreign gas rebreathing technique will be used to measure cardiac output.Operational Protocols
NASA Image: ISS019E018475 - Japan Aerospace Exploration Agency (JAXA) astronaut Koichi Wakata, Expedition 19 flight engineer, prepares to blow into the Pulmonary Function Module/Photoacoustic Analyzer Module (PFM/PAM) rebreathing unit for the Pulmonary Function System (PFS) to begin Day 1 of the ESA cardiological experiment CARD (Long Term Microgravity: A Model for Investigating Mechanisms of Heart Disease. The hardware is located on the Human Research Facility Rack 2 (HRF-2) in the Columbus module.
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NASA Image: ISS020E046971 - View of Astronaut Michael Barratt,Expedition 19/20 flight engineer,working at the ESA cardiological experiment CARD (Long Term Microgravity: A Model for Investigating Mechanisms of Heart Disease) in the U.S. Laboratory.
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