Rodent Research-2 (NASA #2) (Rodent Research-2 (NASA #2)) - 01.15.14
ISS Science for Everyone
Science Objectives for Everyone
Living in space causes several physical changes to the human body, including microscopic changes in the vascular system. Rodent Research-2 determines which changes occur in the blood-brain barrier during spaceflight, as fluid pressure on the brain increases. Understanding the effects of microgravity on brain vasculature could provide insight into space-related neurological changes, such as impaired vision or reduced cognitive ability.
Science Results for Everyone
NASA Ames Research Center, Moffett Field, CA, United States
Sponsoring Space Agency
National Aeronautics and Space Administration (NASA)
Human Exploration and Operations Mission Directorate (HEOMD)
ISS Expedition Duration
September 2014 - March 2015
Previous ISS Missions
Simulating the microgravity, radiation and launch conditions of spaceflight is difficult to do on Earth. Subjecting rats to the real environment of space will provide crucial information about how mammals respond to those stressors. Specifically, understanding how spaceflight causes physical changes in brain vasculature could help explain reported changes in vision during space missions
Rodent Research-2 will demonstrate how changes in blood pressure can affect blood flow to the brain, and how this could affect vision. Understanding the relationship between blood pressure and brain vasculature could provide insights for neuroscience on Earth, including for patients with brain injuries or neurological disorders.