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ISS Science for Everyone

Science Objectives for Everyone
With dust particles present in the International Space Station atmosphere, Airway Monitoring studies the occurrence and indicators of airway inflammation in crewmembers, using ultra-sensitive gas analysers to analyse exhaled air. This helps to highlight any health impacts and to maintain crewmember well-being on future human spaceflight missions, especially longer-duration missions to the Moon and Mars for example, where crewmembers will have to be more self-sufficient in highlighting and avoiding such conditions.
Science Results for Everyone
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The following content was provided by Lars L. Karlsson, Ph.D., and is maintained in a database by the ISS Program Science Office.
Information provided courtesy of the Erasmus Experiment Archive.
Experiment Details

OpNom: Airway Monitoring

Principal Investigator(s)
Lars L. Karlsson, Ph.D., Karolinska Institutet, Stockholm, Sweden

Lars E. Gustafsson, Ph.D., Karolinska Institutet, Stockholm, Sweden
Dag Linnarsson, Karolinska Institute, Stockholm, Sweden
Alain Van Muylem, Universite┬┤ Libre de Bruxelles, Brussells, Belgium

European Space Agency (ESA), Noordwijk, Netherlands

Sponsoring Space Agency
European Space Agency (ESA)

Sponsoring Organization
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Research Benefits
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ISS Expedition Duration 1
September 2014 - March 2015; September 2015 - March 2017

Expeditions Assigned

Previous ISS Missions
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Experiment Description

Research Overview
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Space Applications
On future human exploration missions where a greater degree of self-sufficiency will be necessary to secure a productive and fruitful mission, and with respect to medical diagnostics and treatment, this type of research will form the cornerstone of planning for eventualities that centre on the occurrence of airway inflammation in astronauts. This is done by monitoring airway health through the measurement of exhaled nitric oxide. Monitoring these measurements helps to highlight environmental conditions that exacerbate/alleviate airway inflammation, and helps in the  development of countermeasures to reduce the possibility of its occurrence. This, in turn, can help to optimise the health and performance of astronauts on long-duration exploration missions.

Earth Applications
ESA research has helped in the development of diagnostic tools which quantify airway inflammation, tools which not only help in spaceflight diagnostics, but that also hold applications on earth within diagnostics of similar conditions, for example monitoring of asthma. This research will provide new insights in nitric oxide physiology, which could improve the diagnostic use of exhaled nitric oxide on Earth and thus benefit patients with asthma or other airway inflammatory diseases.

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Operational Requirements
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Operational Protocols
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Decadal Survey Recommendations

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Results/More Information

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Related Websites

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NASA Image ISS042E049017 - ESA astronaut Samantha Cristoforetti on board the International Space Station working with equipment for the Airway Monitoring investigation.

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