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NASA and National Space Biomedical Research Institute Select Research Proposals to Support Crew Health and Performance
May 21, 2012
 

NASA and the National Space Biomedical Research Institute (NSBRI) have selected 29 research proposals from 104 received in response to NASA Research Announcement NNJ11ZSA002NA, "Research and Technology Development to Support Crew Health and Performance in Space Exploration Missions."

Proposals were openly solicited from academia, industry and government laboratories and were judged for scientific merit by non-NASA technical experts. Following external peer review, NASA and NSBRI selected 29 meritorious proposals representing 11 states and 25 institutions. The selected investigations address astronaut health and performance risks for future space exploration missions. These grants are collectively valued at approximately $26 million over their lifetimes of one to three years and are listed below.

NASA Awards

  • Dawn Bowles, Ph.D., Duke University, Proteomic Profiling of Human Heart Tissue Exposed to Microgravity
  • Richard Boyle, Ph.D., NASA Ames Research Center, Inner Ear Otoconia Response in Mice to Micro- and Hyper-gravity
  • Melpo Christofidou-Solomidou, Ph.D., University of Pennsylvania, Novel Double-Hit Mouse Model to Investigate Oxidative Damage from Radiation/ Hyperoxia Related to Space Exploration - Evaluation of Dietary Flaxseed as Countermeasure
  • Scott Dulchavsky, M.D., Ph.D., Henry Ford Health System, Microgravity Associated Compartmental Equilibration
  • Ute Fischer, Ph.D., Georgia Institute of Technology, Protocols for Asynchronous Communication in Space Operations: Communication Analysis
  • Charles Fuller, Ph.D., University of California, Davis, Head-Down Tilt as a Model for Intracranial and Intraocular Pressures, and Retinal Changes during Spaceflight
  • Alan Hargens, Ph.D., University of California, San Diego, Fluid Distribution before, during and after Prolonged Space Flight
  • Steve Kozlowski, Ph.D., Michigan State University, Monitoring and Regulating Teamwork
  • C. Mark Ott, Ph.D., NASA Johnson Space Center, Efficacy of Antimicrobials on Bacteria Cultured in a Spaceflight Analog
  • F. Andrew Ray, Ph.D., KromaTiD, Next Generation Approaches to Chromatid Painting
  • Donna Roberts, M.D, Medical University of South Carolina, Human Cerebral Vascular Autoregulation and Venous Outflow in Response to Microgravity-Induced Cephalad Fluid Redistribution
  • Peter Roma, Ph.D., Institutes for Behavior Resources, Development of an Objective Behavioral Assay of Cohesion to Enhance Composition, Task Performance, and Psychosocial Adaptation in Long-Term Work Groups
  • Michael Stenger, Ph.D., Wyle Science, Technology and Engineering, Distribution of Body Fluids during Long Duration Space Flight and Subsequent Effects on Intraocular Pressure and Vision Disturbance
  • Susana Zanello, Ph.D., Universities Space Research Association, Evaluation of Hindlimb Suspension as a Model to Study Ophthalmic Complications in Microgravity: Ocular Structure and Function and Association with Intracranial Pressure

NSBRI Awards

Cardiovascular Alterations Team

  • Benjamin Levine, M.D., University of Texas Southwestern Medical Center, Effects of Microgravity on Intracranial Pressure
  • Mohan Natarajan, Ph.D., University of Texas Health Science Center, San Antonio, Targeting NO/IKK Signaling to Counteract Hemodynamic Flow-Dependent Endothelial Dysfunction and Vascular Damage after Space Radiation

Human Factors and Performance Team

  • Ann Barrett, Ph.D., U.S. Army Natick Soldier Systems Center, Stabilized Foods for Use in Extended Spaceflight: Preservation of Shelf-Life, Nutrient Content and Acceptability
  • Elizabeth Klerman, M.D., Ph.D., Harvard Medical School - Brigham and Women's Hospital, Ultra-Short Light Pulses as Efficient Countermeasures for Circadian Misalignment and Objective Performance and Subjective Alertness Decrements
  • Steven Lockley, Ph.D., Harvard Medical School - Brigham and Women's Hospital, The ISS Dynamic Lighting Schedule: An in-flight lighting countermeasure to facilitate circadian adaptation, improve sleep and enhance alertness and performance on the International Space Station
  • Debra Schreckenghost, TRACLabs, Automation in Procedures: Guidelines for Allocating Tasks for Performance

Musculoskeletal Alterations Team

  • Henry Donahue, Ph.D., Pennsylvania State University, Integrated Regulation of Bone and Muscle Metabolism by Simulated Microgravity
  • Lori Ploutz-Snyder, Ph.D., Universities Space Research Association, Integrated Resistance and Aerobic Exercise Training with Small Compact Exercise Equipment

Neurobehavioral and Psychosocial Factors

  • David Dinges, Ph.D., University of Pennsylvania, Markers of Susceptibility to Neurobehavioral Decrements in Space Flight
  • Robert Hienz, Ph.D., Johns Hopkins University, Detection and Prevention of Neurobehavioral Vulnerability to Space Radiation
  • Rachael Seidler, Ph.D., University of Michigan, Bed Rest as a Spaceflight Analog to Study Neurocognitive Changes: Extent, Longevity, and Neural Bases

Sensorimotor Adaptation Team

  • Jacob Bloomberg, Ph.D., NASA Johnson Space Center, Developing Predictive Measures of Sensorimotor Adaptability to Produce Customized Countermeasure Prescriptions

Smart Medical Systems and Technology Team

  • Aaron Dentinger, Ph.D., General Electric, Non-Invasive Monitoring of Intracranial Pressure (ICP) with Volumetric Ophthalmic Ultrasound
  • Gary Strangman, Ph.D., Harvard Medical School - Massachusetts General Hospital, Multi-Use Near-Infrared Spectroscopy System for Spaceflight Health Applications
  • Michael Williams, M.D., Sinai Hospital of Baltimore, Comparison of Continuous Non-Invasive and Invasive Intracranial Pressure Measurement
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