Publications - Pharmacotherapeutics

    Pharmacotherapeutics Publications


    Presentations

    • Putcha L. Efficient pharmacotherapeutics is an essential tool for ensuring safety and success of mission to Moon and Mars for permanent human presence in space. 27th Annual International Gravitational Physiology. Osaka, Japan. April 23-28, 2006.
    • Putcha L. In vitro and in vivo assessment of the prototype intranasal promethazince microcapsule formulation. 2005 AAPS National Biotechnology Conferece. 2005.
    • Du J, Gatlin KT, Vaksman Z, Berens KL, Putcha L. Effect of sampling schedule on pharmacokinetic parameter estimates of promethazine in astronauts. 2005.
    • Boyd JL, Shah V, Du B, Vaksman Z, Putcha L. Gastrointestinal function during extended duration in space. 2005.
    • Du J, Vaksman Z, Gatlin KT, Putcha L. Pharmacotherapeutics of intranasal scopolamine - procedures for IND studies with the formulation. 2005.
    • Gatlin KT, Boyd JL, Wang Z, Das H, Putcha L. Pharmacodynamics of promethazine in human subjects. American Society for Clinical Pharmacology & Therapeutics 2005 Annual Meeting. Orlando, FL. March 2-6, 2005.
    • Putcha L. Pharmacodynamics of promethazine in human subjects. American Society for Clinical Pharmacology & Therapeutics 2005 Annual Meeting. Orlando, FL. March 2-5, 2005.
    • Putcha L, Boyd JL, Boster B, Wang Z, Shah V, Berens KL, Sipes WE, Anderson KE. Bioavailability and pharmacodynamics of promethazine in human subjects. Abstracts of the 8th World Congress on Clinical Pharmacology & Therapeutics. 2004.
    • Du J, Berens KL, Putcha L. Development and validation of an LC/MS/MS method for the quantitation of scopolamine and dextroamphetamine. 2004 American Association of Pharmaceutical Scientists Annual Meeting. November 7-11, 2004.
    • Putcha L, Du J, Berens KL. Development and validation of an LC/MS/MS method for the quantitation of scopolamine and dextroamphetamine. 2004 American Association of Pharmaceutical Scientists Annual Meeting. Baltimore, MD. November 7-11, 2004.
    • Putcha L, Wang Z, Boyd JL, Berens KL. LC/MS method for the determination of stable isotops labeled promethazine in human plasma. 2004 American Association of Pharmaceutical Scientists Annual Meeting. November 7-11, 2004.
    • Putcha L, Cintron N, Clark J, Clark J, McMonigal K. Pharmaceutical risk assessment and management in space medicine. 75th Annual Scientific Meeting of Aerospace Medical Association. Anchorage, AK. May 2-6, 2004.
    • Putcha L. Pharmacotherapeutic aspects of space medicine. Animal Research in Support of Human Space Exploration. Woods Hole, MA. April 13-16, 2004.
    • McDonough J, Persyn J, Putcha L. A novel drug delivery system: microcapsule gel formulation of promethazine hydrochloride. NSBRI Investigators' Retreat. Conroe,TX. January 12-15, 2004.
    • Boland EJ, Cranes DL, McDonough J, Putcha L. Evaluation of the response of rat nasal mucosa to microencapsulated promethazine hydrochloride. NSBRI Investigators' Retreat. Conroe,TX. January 12-15, 2004.
    • Putcha L. A LC/MS analysis method for the determination of deglymidodrine levels in human plasma. October 26-30, 2003.
    • Putcha L. Development and validation of stability indicating assay methods for semisolid dosage forms used in the space medical operations. October 26-30, 2003.
    • Putcha L. Interaction between 13C-Urea and glucose breath tests for the detection of pathology associated with gastrointestinal microflora. October 26-30, 2003.
    • Putcha L. Validation of a handheld computer-based performance test battery for pharmacodynamic assessment of neuro-active drugs. September 21-23, 2003.
    • Putcha L. Contributing factors of pharmacotherapeutics in space. 14th IAA Human in Space Symposium. Banff, Canada. May 18-22, 2003.
    • Putcha L, Bacal K. Operational application of increment science. 14th IAA Humans in Space Symposium. Banff, Canada. May 18-22, 2003.
    • Du J, Bayuse T, Shah V, Putcha L. Stability of pharmaceuticals during space flight. 2002 American Association of Pharmaceutical Scientists Annual Meeting. Toronto, Canada. November 10-14, 2002.
    • Putcha L. Development of an intranasal controlled release formulation of promethazine hydrochloride. ESA Meeting Controlled Release Society. July, 2002.
    • Wang Z, Sarabia SF, Bayuse T, Shah V, Putcha L. A sensitive LC/MS method for the determination of promethazine and its metabolites in plasma and saliva. Pittsburgh Conference. New Orleans, LA. March 18-22, 2002.
    • Putcha L. Gender specific pharmacotherapeutics in space. 8th European Symposium on Life Sciences: Life in Space for Life on Earth. Stockholm, Sweden. February, 2002.