The absence of gravity during space flight leads to adaptive changes in central nervous system function. The Neuroscience Laboratories investigates the effects of space flight on the human nervous system, with particular emphasis on posture and gait function, eye-head coordination, perception, space motion sickness and vestibular-autonomic function. The central focus of the laboratory is the development of countermeasures to mitigate the space flight related changes in nervous system function associated with adaptation to microgravity and return to gravitational environments. The laboratory supports ground-based and in-flight investigations, crew health monitoring, risk mitigation operational activities and countermeasures evaluation and validation research.